BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells (Q41897658)

13 October 2017

BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells (English)

1 reference

13 October 2017

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Erik Meijering

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Marcel Reuter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Ihor Smal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Wiggert A van Cappellen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

H Martijn de Gruiter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Adriaan B Houtsmuller

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jeroen Essers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Roland Kanaar

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Claire Wyman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

1 December 2014

1 reference

13 October 2017

Journal of Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

207

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

599-613

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

11 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4259808/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor

1 reference

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Taking it one step at a time in homologous recombination repair

5 June 2018

1 reference

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Androgen receptor complexes probe DNA for recognition sequences by short random interactions

5 June 2018

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5 June 2018

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Endogenous levels of Rad51 and Brca2 are required for homologous recombination and regulated by homeostatic re-balancing.

5 June 2018

1 reference

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A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization

5 June 2018

1 reference

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5 June 2018

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Closed-form density-based framework for automatic detection of cellular morphology changes

5 June 2018

1 reference

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Methods for cell and particle tracking

5 June 2018

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Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains.

5 June 2018

1 reference

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BRCA1 and BRCA2: different roles in a common pathway of genome protection

5 June 2018

1 reference

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Two classes of BRC repeats in BRCA2 promote RAD51 nucleoprotein filament function by distinct mechanisms

5 June 2018

1 reference

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Double-strand break repair-independent role for BRCA2 in blocking stalled replication fork degradation by MRE11.

5 June 2018

1 reference

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Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition.

5 June 2018

1 reference

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ATP-dependent and independent functions of Rad54 in genome maintenance

5 June 2018

1 reference

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Andromeda: a peptide search engine integrated into the MaxQuant environment

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

How to quantify protein diffusion in the bacterial membrane.

5 June 2018

1 reference

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DNA damage regulates the mobility of Brca2 within the nucleoplasm of living cells.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Human BRCA2 protein promotes RAD51 filament formation on RPA-covered single-stranded DNA.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

The breast cancer tumor suppressor BRCA2 promotes the specific targeting of RAD51 to single-stranded DNA.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Purified human BRCA2 stimulates RAD51-mediated recombination

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Regulation of homologous recombination in eukaryotes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

gammaH2AX foci analysis for monitoring DNA double-strand break repair: strengths, limitations and optimization

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Two modules in the BRC repeats of BRCA2 mediate structural and functional interactions with the RAD51 recombinase.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Dre recombinase, like Cre, is a highly efficient site-specific recombinase in E. coli, mammalian cells and mice

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Trends in fluorescence imaging and related techniques to unravel biological information

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Enzymatic assembly of DNA molecules up to several hundred kilobases

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Robust single-particle tracking in live-cell time-lapse sequences

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Single-molecule approach to molecular biology in living bacterial cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Probing intranuclear environments at the single-molecule level

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Generation of an inducible and optimized piggyBac transposon system.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Compartmentalization of androgen receptor protein-protein interactions in living cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Subunit counting in membrane-bound proteins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Gaussian approximations of fluorescence microscope point-spread function models

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Assembly dynamics of microtubules at molecular resolution

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Analysis of DNA recombination and repair proteins in living cells by photobleaching microscopy

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Suppression of the DNA repair defects of BRCA2-deficient cells with heterologous protein fusions

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

A genome-wide, end-sequenced 129Sv BAC library resource for targeting vector construction

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

The LSM 510 META - ConfoCor 2 system: an integrated imaging and spectroscopic platform for single-molecule detection.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Dynamic control of Rad51 recombinase by self-association and interaction with BRCA2

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

A murine model of Nijmegen breakage syndrome

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Precise nanometer localization analysis for individual fluorescent probes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

ATP hydrolysis by mammalian RAD51 has a key role during homology-directed DNA repair

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein.

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Fluorescence correlation spectroscopy reveals fast optical excitation-driven intramolecular dynamics of yellow fluorescent proteins

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 foci formation

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Dynamics of fluorescence fluctuations in green fluorescent protein observed by fluorescence correlation spectroscopy

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

The BRC repeats in BRCA2 are critical for RAD51 binding and resistance to methyl methanesulfonate treatment

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Multiple possible sites of BRCA2 interacting with DNA repair protein RAD51

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Single-molecule microscopy on model membranes reveals anomalous diffusion

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

On/off blinking and switching behaviour of single molecules of green fluorescent protein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

RAB22 and RAB163/mouse BRCA2: proteins that specifically interact with the RAD51 protein

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

A mRad51-GFP antimorphic allele affects homologous recombination and DNA damage sensitivity

5 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Dissecting chromatin interactions in living cells from protein mobility maps.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Random time-scale invariant diffusion and transport coefficients

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Highly inclined thin illumination enables clear single-molecule imaging in cells.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Ionizing radiation-induced foci formation of mammalian Rad51 and Rad54 depends on the Rad51 paralogs, but not on Rad52.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

BAC engineering for the generation of ES cell-targeting constructs and mouse transgenes

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Analysis of mouse Rad54 expression and its implications for homologous recombination.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Rapid switching of TFIIH between RNA polymerase I and II transcription and DNA repair in vivo

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Automatic fluorescent tag detection in 3D with super-resolution: application to the analysis of chromosome movement.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4259808

Single ovalbumin molecules exploring nucleoplasm and nucleoli of living cell nuclei

18 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25488918

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cell cycle control of BRCA2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25488918

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.201405014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

25488918

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25488918%20AND%20SRC:MED&resulttype=core&format=json