Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin (Q41812511)

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scientific article published on March 2001

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English	Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin	scientific article published on March 2001

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Rac mediates cytoskeletal rearrangements and increased cell motility induced by urokinase-type plasminogen activator receptor binding to vitronectin (English)

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

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1 reference

based on heuristic

inferred from title

author name string

L Kjøller

1

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Europe PubMed Central

PMC publication ID

12 October 2017

A Hall

2

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Europe PubMed Central

PMC publication ID

12 October 2017

language of work or name

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publication date

1 March 2001

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Europe PubMed Central

PMC publication ID

12 October 2017

number of pages

13

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Journal of Cell Biology

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Europe PubMed Central

PMC publication ID

12 October 2017

152

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Europe PubMed Central

PMC publication ID

12 October 2017

6

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

1145-1157

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

Urokinase receptor: a molecular organizer in cellular communication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199201

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Urokinase receptor and integrin partnership: coordination of signaling for cell adhesion, migration and growth.

1 reference

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Urokinase receptor-deficient mice have impaired neutrophil recruitment in response to pulmonary Pseudomonas aeruginosa infection

1 reference

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Role of urokinase and its receptor in basal and stimulated colonic epithelial cell migration in vitro

1 reference

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Extracellular-regulated kinase activation and CAS/Crk coupling regulate cell migration and suppress apoptosis during invasion of the extracellular matrix

1 reference

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Identification of a urokinase receptor-integrin interaction site. Promiscuous regulator of integrin function

1 reference

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6 June 2018

Domain 1 of the urokinase receptor (uPAR) is required for uPAR-mediated cell binding to vitronectin

1 reference

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Motility and invasion are differentially modulated by Rho family GTPases

1 reference

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Integrin signalling: a new Cas(t) of characters enters the stage

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A urokinase receptor-associated protein with specific collagen binding properties

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Mapping part of the functional epitope for ligand binding on the receptor for urokinase-type plasminogen activator by site-directed mutagenesis

1 reference

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Mechanisms of signaling through urokinase receptor and the cellular response

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Role of urokinase receptor and caveolin in regulation of integrin signaling.

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Urokinase receptor interacts with alpha(v)beta5 vitronectin receptor, promoting urokinase-dependent cell migration in breast cancer

1 reference

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Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling

1 reference

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Integrin signaling

1 reference

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Myosin light chain kinase functions downstream of Ras/ERK to promote migration of urokinase-type plasminogen activator-stimulated cells in an integrin-selective manner

1 reference

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Urokinase-type plasminogen activator binding to its receptor stimulates tumor cell migration by enhancing integrin-mediated signal transduction

1 reference

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p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

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The urokinase receptor. A cell surface, regulated chemokine.

1 reference

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Rho GTPases control polarity, protrusion, and adhesion during cell movement

1 reference

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Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

1 reference

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Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

1 reference

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6 June 2018

Urokinase-dependent angiogenesis in vitro and diacylglycerol production are blocked by antisense oligonucleotides against the urokinase receptor.

1 reference

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6 June 2018

Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling

1 reference

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6 June 2018

Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes

1 reference

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A role for Cdc42 in macrophage chemotaxis

1 reference

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6 June 2018

Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2199201

6 June 2018

Rho GTPases and the actin cytoskeleton

1 reference

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6 June 2018

A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity.

1 reference

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Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

1 reference

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Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

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Urokinase Receptor Is Associated with the Components of the JAK1/STAT1 Signaling Pathway and Leads to Activation of This Pathway upon Receptor Clustering in the Human Kidney Epithelial Tumor Cell Line TCL-598

1 reference

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Proximity oscillations of complement type 4 (alphaX beta2) and urokinase receptors on migrating neutrophils

1 reference

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Rho GTPases and signaling networks

1 reference

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6 June 2018

Binding of high molecular weight kininogen to human endothelial cells is mediated via a site within domains 2 and 3 of the urokinase receptor

1 reference

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Lymphocyte adhesion molecule ligands and extracellular matrix proteins in gliomas and normal brain: expression of VCAM-1 in gliomas

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The urokinase-type plasminogen activator system in cancer metastasis: A review

1 reference

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6 June 2018

Plasmin and plasminogen activator inhibitor type 1 promote cellular motility by regulating the interaction between the urokinase receptor and vitronectin

1 reference

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Urokinase-type plasminogen activator receptors associate with beta1 and beta3 integrins of fibrosarcoma cells: dependence on extracellular matrix components.

1 reference

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6 June 2018

Is plasminogen activator inhibitor-1 the molecular switch that governs urokinase receptor-mediated cell adhesion and release?

1 reference

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6 June 2018

Domain interplay in the urokinase receptor. Requirement for the third domain in high affinity ligand binding and demonstration of ligand contact sites in distinct receptor domains.

1 reference

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6 June 2018

Regulation of integrin function by the urokinase receptor

1 reference

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6 June 2018

The urokinase receptor (CD87) facilitates CD11b/CD18-mediated adhesion of human monocytes

1 reference

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6 June 2018

Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect

1 reference

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6 June 2018

Actin-based cell motility and cell locomotion

1 reference

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Cell migration: a physically integrated molecular process

1 reference

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Biology and biochemistry of proteinases in tumor invasion.

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6 June 2018

Distribution and lateral mobility of the urokinase-receptor complex at the cell surface.

1 reference

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6 June 2018

The urokinase receptor is required for human monocyte chemotaxis in vitro

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Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases

1 reference

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A role for Rac in Tiam1-induced membrane ruffling and invasion

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Activation of the small GTP-binding proteins rho and rac by growth factor receptors.

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PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase

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1 reference

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The urokinase receptor is a major vitronectin-binding protein on endothelial cells

1 reference

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inferred from PubMed ID database lookup

Mac-1 (CD11b/CD18) and the urokinase receptor (CD87) form a functional unit on monocytic cells

1 reference

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Melanoma cell migration on vitronectin: regulation by components of the plasminogen activation system

1 reference

https://pubmed.ncbi.nlm.nih.gov/11257116

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Localization of urokinase to focal adhesions by human fibrosarcoma cells synthesizing recombinant vitronectin

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1 reference

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1 reference

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1 reference

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The intact urokinase receptor is required for efficient vitronectin binding: receptor cleavage prevents ligand interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/11257116

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Binding of human urokinase-type plasminogen activator to its receptor: residues involved in species specificity and binding

1 reference

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Src-dependence and pertussis-toxin sensitivity of urokinase receptor-dependent chemotaxis and cytoskeleton reorganization in rat smooth muscle cells

1 reference

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Vitronectin regulates the synthesis and localization of urokinase-type plasminogen activator in HT-1080 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11257116

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based on heuristic

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Ligand interaction between urokinase-type plasminogen activator and its receptor probed with 8-anilino-1-naphthalenesulfonate. Evidence for a hydrophobic binding site exposed only on the intact receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/11257116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of the urokinase receptor as an adhesion receptor for vitronectin

1 reference

https://pubmed.ncbi.nlm.nih.gov/11257116

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1083/JCB.152.6.1145

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 October 2017

ResearchGate publication ID

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