Activation of forkhead box O transcription factors by oncogenic BRAF promotes p21cip1-dependent senescence. (Q41680604)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

title

Activation of forkhead box O transcription factors by oncogenic BRAF promotes p21cip1-dependent senescence (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Leisl M Packer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Anna A Szypowska

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Paulien E Riedl-Polderman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Niels J F van den Broek

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Alain de Bruin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Tobias B Dansen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Arjan B Brenkman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Boudewijn M T Burgering

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

language of work or name

English

0 references

publication date

19 October 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

page(s)

8526-8536

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

The cunning little vixen: Foxo and the cycle of life and death

15 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Oncogenic Braf induces melanocyte senescence and melanoma in mice

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Braf(V600E) cooperates with Pten loss to induce metastatic melanoma

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

The peptidyl-isomerase Pin1 regulates p27kip1 expression through inhibition of Forkhead box O tumor suppressors

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

FOXO3A genotype is strongly associated with human longevity

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Melanomagenesis: overcoming the barrier of melanocyte senescence

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Cellular senescence: when bad things happen to good cells

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Cellular senescence in cancer and aging

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Stressing the role of FoxO proteins in lifespan and disease

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Tumor necrosis factor-alpha blocks apoptosis in melanoma cells when BRAF signaling is inhibited

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

The role of cell cycle regulatory proteins in the pathogenesis of melanoma.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Cellular senescence in naevi and immortalisation in melanoma: a role for p16?

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Hydrogen peroxide: a signaling messenger

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

BRAFE600-associated senescence-like cell cycle arrest of human naevi

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Use of human tissue to assess the oncogenic activity of melanoma-associated mutations

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

The RAF proteins take centre stage

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Guilty as charged: B-RAF is a human oncogene

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Aging: a theory based on free radical and radiation chemistry

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

High frequency of BRAF mutations in nevi

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Mutations of the BRAF gene in human cancer

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Redox-dependent signal transduction

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Direct control of the Forkhead transcription factor AFX by protein kinase B

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Senescence of human fibroblasts induced by oncogenic Raf.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Raf-Induced Proliferation or Cell Cycle Arrest Is Determined by the Level of Raf Activity with Arrest Mediated by p21Cip1

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

A C. elegans mutant that lives twice as long as wild type

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

WAF1, a potential mediator of p53 tumor suppression

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Genetic cooperation between p21Cip1 and INK4 inhibitors in cellular senescence and tumor suppression.

6 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

A negative feedback signaling network underlies oncogene-induced senescence

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

The power and the promise of oncogene-induced senescence markers.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Mutations associated with familial melanoma impair p16INK4 function.

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Metastasizing Melanoma Formation Caused by Expression of Activated N-RasQ61Kon an INK4a-Deficient Background

18 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds

2 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2989643

c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20959475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20959475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Oncogene activation in melanocytes links reactive oxygen to multinucleated phenotype and senescence

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20959475

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-10-1563

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

PubMed publication ID

20959475

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20959475%20AND%20SRC:MED&resulttype=core&format=json