Loss of PTEN expression is associated with aggressive behavior and poor prognosis in Middle Eastern triple-negative breast cancer. (Q40931689)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25981902%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Loss of PTEN expression is associated with aggressive behavior and poor prognosis in Middle Eastern triple-negative breast cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25981902%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

Abdul K Siraj

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8 March 2020

Sarita Prabhakaran

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8 March 2020

Zeenath Jehan

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8 March 2020

Dahish Ajarim

1 reference

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8 March 2020

Fouad Al-Dayel

1 reference

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8 March 2020

Khawla S Al-Kuraya

1 reference

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8 March 2020

language of work or name

English

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publication date

16 May 2015

1 reference

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Breast Cancer Research and Treatment

8 March 2020

published in

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8 March 2020

volume

151

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8 March 2020

issue

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8 March 2020

page(s)

541-553

1 reference

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Global cancer statistics, 2012

8 March 2020

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21 January 2018

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Potential prognostic value of heat-shock protein 90 in the presence of phosphatidylinositol-3-kinase overexpression or loss of PTEN, in invasive breast cancers.

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Loss of PTEN expression is associated with IGFBP2 expression, younger age, and late stage in triple-negative breast cancer

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Genome and transcriptome sequencing in prospective metastatic triple-negative breast cancer uncovers therapeutic vulnerabilities

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Dysregulated PI3K/Akt/PTEN pathway is a marker of a short disease-free survival in node-negative breast carcinoma

21 January 2018

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Triple negative breast tumors in African-American and Hispanic/Latina women are high in CD44+, low in CD24+, and have loss of PTEN.

21 January 2018

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Role of HER3 expression and PTEN loss in patients with HER2-overexpressing metastatic breast cancer (MBC) who received taxane plus trastuzumab treatment

21 January 2018

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Comprehensive analysis of PTEN status in breast carcinomas

21 January 2018

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Tissue microarrays for high-throughput molecular profiling of tumor specimens

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Effect of ASCO/CAP guidelines for determining ER status on molecular subtype.

21 January 2018

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Optimal protocol for PTEN immunostaining; role of analytical and preanalytical variables in PTEN staining in normal and neoplastic endometrial, breast, and prostatic tissues

21 January 2018

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Immunohistochemical expression of PTEN and phosphorylated Akt are not correlated with clinical outcome in breast cancer patients treated with trastuzumab-containing neo-adjuvant chemotherapy

21 January 2018

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PIK3CA mutations and PTEN loss correlate with similar prognostic factors and are not mutually exclusive in breast cancer

21 January 2018

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Evaluation of the association of PIK3CA mutations and PTEN loss with efficacy of trastuzumab therapy in metastatic breast cancer.

21 January 2018

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Impact of PTEN protein expression on benefit from adjuvant trastuzumab in early-stage human epidermal growth factor receptor 2-positive breast cancer in the North Central Cancer Treatment Group N9831 trial

21 January 2018

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The role of PTEN and its signalling pathways, including AKT, in breast cancer; an assessment of relationships with other prognostic factors and with outcome.

21 January 2018

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The Akt pathway in human breast cancer: a tissue-array-based analysis

21 January 2018

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PTEN, PIK3CA, p-AKT, and p-p70S6K status: association with trastuzumab response and survival in patients with HER2-positive metastatic breast cancer.

21 January 2018

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Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells

21 January 2018

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Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway

21 January 2018

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MGMT and PTEN as potential prognostic markers in breast cancer

21 January 2018

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10.1007/S10549-015-3430-3

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25981902%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

8 March 2020

1045901149

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25981902%20AND%20SRC:MED&resulttype=core&format=json