Inhibition of NFkappaB increases the efficacy of cisplatin in in vitro and in vivo ovarian cancer models (Q40577628)

21 September 2017

title

Inhibition of NFkappaB increases the efficacy of cisplatin in in vitro and in vivo ovarian cancer models (English)

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21 September 2017

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Seiji Mabuchi

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21 September 2017

Masahide Ohmichi

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21 September 2017

Yukihiro Nishio

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21 September 2017

Tadashi Hayasaka

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21 September 2017

Akiko Kimura

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21 September 2017

Tsuyoshi Ohta

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21 September 2017

Maki Saito

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21 September 2017

Jun Kawagoe

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21 September 2017

Kazuhiro Takahashi

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21 September 2017

Namiko Yada-Hashimoto

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21 September 2017

Masahiro Sakata

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21 September 2017

Teiichi Motoyama

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21 September 2017

Hirohisa Kurachi

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21 September 2017

Keiichi Tasaka

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21 September 2017

Yuji Murata

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21 September 2017

language of work or name

English

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publication date

16 March 2004

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Journal of Biological Chemistry

21 September 2017

published in

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21 September 2017

volume

279

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21 September 2017

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21 September 2017

page(s)

23477-23485

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Inhibition of phosphorylation of BAD and Raf-1 by Akt sensitizes human ovarian cancer cells to paclitaxel

21 September 2017

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

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AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

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BCR/ABL regulates expression of the cyclin-dependent kinase inhibitor p27Kip1 through the phosphatidylinositol 3-Kinase/AKT pathway

21 January 2018

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Cyclooxygenase regulates angiogenesis induced by colon cancer cells

21 January 2018

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Blockade of NF-kappaB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis

21 January 2018

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Transcriptional cross talk between NF-kappaB and p53.

21 January 2018

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NF-kappaB as a therapeutic target in cancer

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DNA damaging agents induce expression of Fas ligand and subsequent apoptosis in T lymphocytes via the activation of NF-kappa B and AP-1.

21 January 2018

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NF-kappaB is activated and promotes cell death in focal cerebral ischemia

21 January 2018

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

21 January 2018

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Suppression of TNF-alpha-induced apoptosis by NF-kappaB

21 January 2018

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

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Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

21 January 2018

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Basal levels and patterns of anticancer drug-induced activation of nuclear factor-kappaB (NF-kappaB), and its attenuation by tamoxifen, dexamethasone, and curcumin in carcinoma cells

21 January 2018

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Increase of the resistance of human cervical carcinoma cells to cisplatin by inhibition of the MEK to ERK signaling pathway partly via enhancement of anticancer drug-induced NF kappa B activation

21 January 2018

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Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion.

21 January 2018

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Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells

21 January 2018

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Inhibition of extracellular signal-regulated protein kinase or c-Jun N-terminal protein kinase cascade, differentially activated by cisplatin, sensitizes human ovarian cancer cell line

21 January 2018

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The role of constitutive NF-kappaB activity in PC-3 human prostate cancer cell invasive behavior

21 January 2018

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Crystal structure of p50/p65 heterodimer of transcription factor NF-kappaB bound to DNA

21 January 2018

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NF-kappa B: ten years after

21 January 2018

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

21 January 2018

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IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

21 January 2018

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Nuclear factor (NF)-kappaB-regulated X-chromosome-linked iap gene expression protects endothelial cells from tumor necrosis factor alpha-induced apoptosis.

21 January 2018

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Cerivastatin, an inhibitor of HMG-CoA reductase, inhibits the signaling pathways involved in the invasiveness and metastatic properties of highly invasive breast cancer cell lines: an in vitro study

21 January 2018

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Role of NF-κB in p53-mediated programmed cell death

21 January 2018

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

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Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

21 January 2018

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Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

21 January 2018

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Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

21 January 2018

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The proteasome--an emerging therapeutic target in cancer

21 January 2018

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Cancer research. Taking garbage in, tossing cancer out?

21 January 2018

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The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M313709200

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21 September 2017

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