The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR. (Q40541045)

21 September 2017

title

The tumor-specific de2-7 epidermal growth factor receptor (EGFR) promotes cells survival and heterodimerizes with the wild-type EGFR. (English)

1 reference

21 September 2017

Rodney B Luwor

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Terrance G Johns

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Hong-Jian Zhu

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21 September 2017

Francesca Walker

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21 September 2017

Angela A Vitali

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21 September 2017

Rushika M Perera

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21 September 2017

Antony W Burgess

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21 September 2017

Andrew M Scott

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21 September 2017

language of work or name

English

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publication date

1 August 2004

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21 September 2017

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21 September 2017

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21 September 2017

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21 September 2017

page(s)

6095-6104

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Receptor dimerization is not a factor in the signalling activity of a transforming variant epidermal growth factor receptor (EGFRvIII)

21 September 2017

cites work

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Cellular survival: a play in three Akts

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STAT activation by epidermal growth factor (EGF) and amphiregulin. Requirement for the EGF receptor kinase but not for tyrosine phosphorylation sites or JAK1.

21 January 2018

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Mechanisms and consequences of activation of protein kinase B/Akt

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Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival

21 January 2018

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Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers

21 January 2018

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The rapamycin-sensitive signal transduction pathway as a target for cancer therapy

21 January 2018

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The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

21 January 2018

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Inhibition of phosphatidylinositol 3-kinase signaling negates the growth advantage imparted by a mutant epidermal growth factor receptor on human glioblastoma cells

21 January 2018

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Prognostic value of tumour associated antigen immunoreactivity and apoptosis in cerebral glioblastomas: an analysis of 168 cases

21 January 2018

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EGF mutant receptor vIII as a molecular target in cancer therapy

21 January 2018

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Inhibition of protein-tyrosine kinases by tyrphostins

21 January 2018

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Activation of extracellular-regulated kinases by normal and mutant EGF receptors

21 January 2018

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Differential modulation of mitogen-activated protein (MAP) kinase/extracellular signal-related kinase kinase and MAP kinase activities by a mutant epidermal growth factor receptor

21 January 2018

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Constitutive Activation of Phosphatidylinositol 3-Kinase by a Naturally Occurring Mutant Epidermal Growth Factor Receptor

21 January 2018

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A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

21 January 2018

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Inhibition of a naturally occurring EGFR oncoprotein by the p185neu ectodomain: implications for subdomain contributions to receptor assembly.

21 January 2018

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Evidence for the differential expression of a variant EGF receptor protein in human prostate cancer

21 January 2018

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Il-3-dependent mouse clones that express B-220 surface antigen, contain Ig genes in germ-line configuration, and generate B lymphocytes in vivo.

21 January 2018

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IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled

21 January 2018

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The epidermal growth factor receptor couples transforming growth factor-alpha, heparin-binding epidermal growth factor-like factor, and amphiregulin to Neu, ErbB-3, and ErbB-4

21 January 2018

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The cellular response to neuregulins is governed by complex interactions of the erbB receptor family

21 January 2018

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Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas

21 January 2018

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Biochemical characterization of mutant EGF receptors expressed in the hemopoietic cell line BaF/3.

21 January 2018

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Activation of the Ras/mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation

21 January 2018

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The class III variant of the epidermal growth factor receptor (EGFRvIII): characterization and utilization as an immunotherapeutic target.

21 January 2018

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Mitogen-activated protein kinase kinase activity is required for the G(2)/M transition of the cell cycle in mammalian fibroblasts

21 January 2018

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Sustained mitogen-activated protein kinase activation is induced by transforming erbB receptor complexes

21 January 2018

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Epidermal growth factor receptor: association of extracellular domain negatively regulates intracellular kinase activation in the absence of ligand

21 January 2018

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'Loop' domain deletional mutant of Bcl-xL is as effective as p29Bcl-xL in inhibiting radiation-induced cytosolic accumulation of cytochrome c (cyt c), caspase-3 activity, and apoptosis

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

A monoclonal antibody to the human epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207870

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1207870

1 reference

Dimensions Publication ID

21 September 2017

1051858114

0 references

1 reference