Inhibition of phosphatidylinostol 3-kinase uncouples H2O2-induced senescent phenotype and cell cycle arrest in normal human diploid fibroblasts (Q40537788)

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scientific article published on August 2004

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English	Inhibition of phosphatidylinostol 3-kinase uncouples H2O2-induced senescent phenotype and cell cycle arrest in normal human diploid fibroblasts	scientific article published on August 2004

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scholarly article

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Europe PubMed Central

PubMed publication ID

21 September 2017

Inhibition of phosphatidylinostol 3-kinase uncouples H2O2-induced senescent phenotype and cell cycle arrest in normal human diploid fibroblasts (English)

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Europe PubMed Central

PubMed publication ID

21 September 2017

author name string

Yong Wang

1

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21 September 2017

Aimin Meng

2

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21 September 2017

Daohong Zhou

3

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21 September 2017

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publication date

1 August 2004

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21 September 2017

Experimental Cell Research

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21 September 2017

298

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21 September 2017

1

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21 September 2017

188-196

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21 September 2017

Replicative senescence revisited

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Putting the stress on senescence

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Requirement for p27(KIP1) in retinoblastoma protein-mediated senescence

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Measurements of hydrogen peroxide induced premature senescence: senescence-associated beta-galactosidase and DNA synthesis index in human diploid fibroblasts with down-regulated p53 or Rb.

1 reference

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Uncoupling between phenotypic senescence and cell cycle arrest in aging p21-deficient fibroblasts

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Rapid reversion of aging phenotypes by nicotinamide through possible modulation of histone acetylation

1 reference

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A positive role of phosphatidylinositol 3-kinase in aging phenotype expression in cultured human diploid fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.012

7 January 2021

Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

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Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes

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Implication of phosphatidylinositol 3-kinase membrane recruitment in hydrogen peroxide-induced activation of PI3K and Akt.

1 reference

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The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2

1 reference

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Signals of oxidant-induced cardiomyocyte hypertrophy: key activation of p70 S6 kinase-1 and phosphoinositide 3-kinase

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A Mammalian bromodomain protein, brd4, interacts with replication factor C and inhibits progression to S phase

1 reference

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7 January 2021

Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts

1 reference

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Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology

1 reference

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Role of the Raf/MEK/ERK and the PI3K/Akt(PKB) pathways in fibroblast senescence

1 reference

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

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SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

1 reference

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Differentiation between senescence (M1) and crisis (M2) in human fibroblast cultures

1 reference

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FAK is the upstream signal protein of the phosphatidylinositol 3-kinase-Akt survival pathway in hydrogen peroxide-induced apoptosis of a human glioblastoma cell line

1 reference

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7 January 2021

Synthesis and function of 3-phosphorylated inositol lipids

1 reference

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P13-kinase inhibition induces dauer formation, thermotolerance and longevity in C. elegans.

1 reference

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A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

1 reference

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7 January 2021

Inhibition of the Phosphoinositide 3-Kinase Pathway Induces a Senescence-like Arrest Mediated by p27Kip1

1 reference

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7 January 2021

Inhibition of the Phosphatidylinositol 3-Kinase/p70S6-Kinase Pathway Induces B16 Melanoma Cell Differentiation

1 reference

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Phosphatidylinositol 3-kinase is a negative regulator of cellular differentiation

1 reference

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Replicative senescence and oxidant-induced premature senescence. Beyond the control of cell cycle checkpoints

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.012

7 January 2021

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10.1016/J.YEXCR.2004.04.012

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 September 2017

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