Putting the stress on senescence (Q34430830)

2 August 2017

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title

Putting the stress on senescence (English)

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ORCID Public Data File 2021

2 August 2017

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author name string

Serrano M

series ordinal

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2 August 2017

Blasco MA

series ordinal

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2 August 2017

publication date

1 December 2001

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Current Opinion in Cell Biology

2 August 2017

published in

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2 August 2017

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2 August 2017

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2 August 2017

page(s)

748-753

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

2 August 2017

1 reference

7 January 2021

The role of senescence and immortalization in carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Human embryonic germ cell derivatives express a broad range of developmentally distinct markers and proliferate extensively in vitro

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Telomeres and telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Benefits of bad telomeres

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Telomere dysfunction and evolution of intestinal carcinoma in mice and humans

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

New link in a web of human genes

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Putative telomere-independent mechanisms of replicative aging reflect inadequate growth conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Expression of the telomerase catalytic subunit, hTERT, induces resistance to transforming growth factor beta growth inhibition in p16INK4A(-) human mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Tumor suppressors and oncogenes in cellular senescence.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Genetic and epigenetic changes in human epithelial cells immortalized by telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Evidence for a telomere-independent "clock" limiting RAS oncogene-driven proliferation of human thyroid epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

p19ARF links the tumour suppressor p53 to Ras

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Escape from premature senescence is not sufficient for oncogenic transformation by Ras.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Senescence of human fibroblasts induced by oncogenic Raf.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

JunD protects cells from p53-dependent senescence and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Atmospheric carbon dioxide concentrations over the past 60 million years

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Histone deacetylases in replicative senescence: evidence for a senescence-specific form of HDAC-2

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Cellular and molecular mechanisms of stress-induced premature senescence (SIPS) of human diploid fibroblasts and melanocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Cellular senescence as a tumor-protection mechanism: the essential role of counting

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Molecular mechanisms of the biological clock in cultured fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Expression of senescence-associated beta-galactosidase in enlarged prostates from men with benign prostatic hyperplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Cellular senescence after single and repeated balloon catheter denudations of rabbit carotid arteries

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Replicative senescence in normal liver, chronic hepatitis C, and hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Differential effects of p19(Arf) and p16(Ink4a) loss on senescence of murine bone marrow-derived preB cells and macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Role of p14(ARF) in replicative and induced senescence of human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Lack of replicative senescence in cultured rat oligodendrocyte precursor cells

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https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

Lack of replicative senescence in normal rodent glia

1 reference

https://api.crossref.org/works/10.1016%2FS0955-0674%2800%2900278-7

7 January 2021

10.1016/S0955-0674(00)00278-7

Identifiers

DOI

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2 August 2017

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