Processing mutations located throughout the human multidrug resistance P-glycoprotein disrupt interactions between the nucleotide binding domains. (Q40537131)

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scientific article published on 9 July 2004

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English	Processing mutations located throughout the human multidrug resistance P-glycoprotein disrupt interactions between the nucleotide binding domains.	scientific article published on 9 July 2004

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scholarly article

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30 December 2019

Processing mutations located throughout the human multidrug resistance P-glycoprotein disrupt interactions between the nucleotide binding domains (English)

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30 December 2019

multiple drug resistance

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based on heuristic

inferred from title

1

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30 December 2019

author name string

M Claire Bartlett

2

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30 December 2019

David M Clarke

3

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30 December 2019

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9 July 2004

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30 December 2019

Journal of Biological Chemistry

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30 December 2019

279

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30 December 2019

37

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30 December 2019

38395-38401

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30 December 2019

Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Cystic fibrosis transmembrane conductance regulator. Structure and function of an epithelial chloride channel

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Cystic fibrosis transmembrane conductance regulator has an altered structure when its maturation is inhibited

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

The cystic fibrosis mutation (delta F508) does not influence the chloride channel activity of CFTR.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Membrane topology of a cysteine-less mutant of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

The packing of the transmembrane segments of human multidrug resistance P-glycoprotein is revealed by disulfide cross-linking analysis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Determining the dimensions of the drug-binding domain of human P-glycoprotein using thiol cross-linking compounds as molecular rulers

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Introduction of the most common cystic fibrosis mutation (Delta F508) into human P-glycoprotein disrupts packing of the transmembrane segments.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

The "LSGGQ" motif in each nucleotide-binding domain of human P-glycoprotein is adjacent to the opposing walker A sequence

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Disulfide cross-linking analysis shows that transmembrane segments 5 and 8 of human P-glycoprotein are close together on the cytoplasmic side of the membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Val133 and Cys137 in transmembrane segment 2 are close to Arg935 and Gly939 in transmembrane segment 11 of human P-glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

DNA sequencing with chain-terminating inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Rapid purification of human P-glycoprotein mutants expressed transiently in HEK 293 cells by nickel-chelate chromatography and characterization of their drug-stimulated ATPase activities.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Superfolding of the partially unfolded core-glycosylated intermediate of human P-glycoprotein into the mature enzyme is promoted by substrate-induced transmembrane domain interactions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Cross-linking of human multidrug resistance P-glycoprotein by the substrate, tris-(2-maleimidoethyl)amine, is altered by ATP hydrolysis. Evidence for rotation of a transmembrane helix.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

P-glycoprotein. Associations between domains and between domains and molecular chaperones

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

ATP binding to the motor domain from an ABC transporter drives formation of a nucleotide sandwich dimer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

A Tweezers-like Motion of the ATP-Binding Cassette Dimer in an ABC Transport Cycle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Drug binding in human P-glycoprotein causes conformational changes in both nucleotide-binding domains.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

P-glycoprotein Is Stably Inhibited by Vanadate-induced Trapping of Nucleotide at a Single Catalytic Site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

The E. coli BtuCD structure: a framework for ABC transporter architecture and mechanism

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Cotranslational folding of globin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Cotranslational Protein Folding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Cooperative, ATP-dependent association of the nucleotide binding cassettes during the catalytic cycle of ATP-binding cassette transporters

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

The transmembrane domains of the human multidrug resistance P-glycoprotein are sufficient to mediate drug binding and trafficking to the cell surface.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Correction of Defective Protein Kinesis of Human P-glycoprotein Mutants by Substrates and Modulators

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Mutational Analysis of the Predicted First Transmembrane Segment of Each Homologous Half of Human P-glycoprotein Suggests That They Are Symmetrically Arranged in the Membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M405623200

21 January 2018

Identifiers

10.1074/JBC.M405623200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15247215%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15247215%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

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