Structure of nucleotide-binding domain 1 of the cystic fibrosis transmembrane conductance regulator (Q27642825)

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Sean G Buchanan

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Stephen K Burley

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Kris Conners

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Mark Dickey

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Michael Dorwart

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Richard Fowler

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Xia Gao

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Wayne A Hendrickson

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John F Hunt

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Margaret C Kearins

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Don Lorimer

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Peter C Maloney

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Kai W Post

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Kanagalaghatta R Rajashankar

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Marc E Rutter

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J Michael Sauder

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Stephanie Shriver

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Patrick H Thibodeau

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Philip J Thomas

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Marie Zhang

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Xun Zhao

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Spencer Emtage

A Tweezers-like Motion of the ATP-Binding Cassette Dimer in an ABC Transport Cycle

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language of work or name

English

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publication date

28 January 2004

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282-93

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cites work

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Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily

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Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast

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Crystal structure of the ATP-binding subunit of an ABC transporter

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Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA

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Cystic fibrosis: a worldwide analysis of CFTR mutations--correlation with incidence data and application to screening

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Structure of MsbA from Vibrio cholera: a multidrug resistance ABC transporter homolog in a closed conformation

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Signals for COPII-dependent export from the ER: what's the ticket out?

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Rescuing protein conformation: prospects for pharmacological therapy in cystic fibrosis

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Domain-domain associations in cystic fibrosis transmembrane conductance regulator

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Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by its R domain

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Severed channels probe regulation of gating of cystic fibrosis transmembrane conductance regulator by its cytoplasmic domains

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Nucleotide-binding domain 1 of cystic fibrosis transmembrane conductance regulator production of a suitable protein for structural studies

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Severed molecules functionally define the boundaries of the cystic fibrosis transmembrane conductance regulator's NH(2)-terminal nucleotide binding domain

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A recombinant peptide model of the first nucleotide-binding fold of the cystic fibrosis transmembrane conductance regulator: comparison of wild-type and delta F508 mutant forms

29 September 2017

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Alteration of the cystic fibrosis transmembrane conductance regulator folding pathway

29 September 2017

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The cystic fibrosis transmembrane conductance regulator. Overexpression, purification, and characterization of wild type and delta F508 mutant forms of the first nucleotide binding fold in fusion with the maltose-binding protein

29 September 2017

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The first nucleotide binding fold of the cystic fibrosis transmembrane conductance regulator can function as an active ATPase

29 September 2017

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Nucleotide-binding properties of native and cold-treated mitochondrial ATPase

29 September 2017

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Cystic fibrosis transmembrane conductance regulator: the NBF1+R (nucleotide-binding fold 1 and regulatory domain) segment acting alone catalyses a Co2+/Mn2+/Mg2+-ATPase activity markedly inhibited by both Cd2+ and the transition-state analogue ortho

29 September 2017

1 reference

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Optimizing Shake-and-Bake for proteins.

2 June 2018

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Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271750

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

2 June 2018

1 reference

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The "LSGGQ" motif in each nucleotide-binding domain of human P-glycoprotein is adjacent to the opposing walker A sequence

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271750

Action of recombinant human apoptotic endonuclease G on naked DNA and chromatin substrates: cooperation with exonuclease and DNase I.

27 November 2018

1 reference

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Expression and characterization of the NBD1-R domain region of CFTR: evidence for subunit-subunit interactions

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271750

Stimulation of CFTR activity by its phosphorylated R domain

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1271750

CFTR activation: additive effects of stimulatory and inhibitory phosphorylation sites in the R domain

27 November 2018

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Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

27 November 2018

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Structure and mechanism of ABC transporters

27 November 2018

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12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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12 December 2020

Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites

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12 December 2020

The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells

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12 December 2020

Association of domains within the cystic fibrosis transmembrane conductance regulator

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12 December 2020

Localization and suppression of a kinetic defect in cystic fibrosis transmembrane conductance regulator folding

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12 December 2020

Modeling of nucleotide binding domains of ABC transporter proteins based on a F1-ATPase/recA topology: structural model of the nucleotide binding domains of the cystic fibrosis transmembrane conductance regulator (CFTR)

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12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600040

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1 reference

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PubMed publication ID

14685259

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