DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks. (Q40497393)

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4 January 2020

title

DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks (English)

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4 January 2020

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4 January 2020

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4 January 2020

Jérôme Drouet

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4 January 2020

Christine Delteil

series ordinal

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4 January 2020

Jacques Lefrançois

series ordinal

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4 January 2020

Bernard Salles

series ordinal

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4 January 2020

language of work or name

English

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publication date

31 October 2004

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Journal of Biological Chemistry

4 January 2020

published in

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4 January 2020

volume

280

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issue

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4 January 2020

page(s)

7060-7069

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Genetic instabilities in human cancers

4 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

The role of DNA breaks in genomic instability and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Sensing and repairing DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Chromosomal stability and the DNA double-stranded break connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Mending the Break: Two DNA Double-Strand Break Repair Machines in Eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Repair of DNA double strand breaks by non-homologous end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Mechanism and regulation of human non-homologous DNA end-joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Nonhomologous end joining and V(D)J recombination require an additional factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Distinct pathways of nonhomologous end joining that are differentially regulated by DNA-dependent protein kinase-mediated phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Autophosphorylation of the catalytic subunit of the DNA-dependent protein kinase is required for efficient end processing during DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

The role of DNA dependent protein kinase in synapsis of DNA ends.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Transient association of Ku with nuclear substrates characterized using fluorescence photobleaching

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Complementation of the radiosensitive M059J cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Nuclear retention of ATM at sites of DNA double strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

DNA damage and mutagenesis by radiomimetic DNA-cleaving agents: bleomycin, neocarzinostatin and other enediynes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Induction and repair of DNA damage in normal and ataxiatelangiectasia skin fibroblasts treated with neocarzinostatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Pathways of DNA double-strand break repair during the mammalian cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

The mammalian XRCC genes: their roles in DNA repair and genetic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

A means to a DNA end: the many roles of Ku.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Human MRE11 is inactivated in mismatch repair-deficient cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

DNA replication but not nucleotide excision repair is required for UVC-induced replication protein A phosphorylation in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Initiation of DNA fragmentation during apoptosis induces phosphorylation of H2AX histone at serine 139

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Ku stimulation of DNA ligase IV-dependent ligation requires inward movement along the DNA molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Interactions of the DNA ligase IV-XRCC4 complex with DNA ends and the DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Impact of DNA ligase IV on the fidelity of end joining in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Defining interactions between DNA-PK and ligase IV/XRCC4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

The XRCC4 gene product is a target for and interacts with the DNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

The defect in murine severe combined immune deficiency: joining of signal sequences but not coding segments in V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

DNA-PK-dependent binding of DNA ends to plasmids containing nuclear matrix attachment region DNA sequences: evidence for assembly of a repair complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Genetic analysis of the DNA-dependent protein kinase reveals an inhibitory role of Ku in late S-G2 phase DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Lack of correlation between ATM protein expression and tumour cell radiosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

Identification of DNA-PKcs phosphorylation sites in XRCC4 and effects of mutations at these sites on DNA end joining in a cell-free system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200

DNA-PK phosphorylation sites in XRCC4 are not required for survival after radiation or for V(D)J recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M410746200