Human MRE11 is inactivated in mismatch repair-deficient cancers (Q33757629)

29 July 2017

title

Human MRE11 is inactivated in mismatch repair-deficient cancers (English)

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29 July 2017

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Alessandra Viel

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29 July 2017

Giuseppe Giannini

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29 July 2017

Elisabetta Ristori

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29 July 2017

Fabio Cerignoli

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29 July 2017

Christian Rinaldi

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29 July 2017

Massimo Zani

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29 July 2017

Laura Ottini

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29 July 2017

Marco Crescenzi

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29 July 2017

Stefano Martinotti

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29 July 2017

Margherita Bignami

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29 July 2017

Luigi Frati

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29 July 2017

Isabella Screpanti

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29 July 2017

Alberto Gulino

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29 July 2017

publication date

15 February 2002

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29 July 2017

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

248-254

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Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex

29 July 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

hMRE11: genomic structure and a null mutation identified in a transcript protected from nonsense-mediated mRNA decay

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

DNA double-strand breaks: signaling, repair and the cancer connection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

Alterations of the double-strand break repair gene MRE11 in cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

DNA damage-dependent nuclear dynamics of the Mre11 complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

ATM-dependent phosphorylation of nibrin in response to radiation exposure

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

The Mre11 complex and ATM: collaborating to navigate S phase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

Mantle cell lymphoma is characterized by inactivation of the ATM gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

In situ visualization of DNA double-strand break repair in human fibroblasts

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

Ataxia-telangiectasia and the Nijmegen breakage syndrome: related disorders but genes apart

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

Functional analysis of the polypyrimidine tract in pre-mRNA splicing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

Microsatellite instability in cancer of the proximal colon

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

Clues to the pathogenesis of familial colorectal cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

Mutations in the Nijmegen Breakage Syndrome gene (NBS1) in childhood acute lymphoblastic leukemia (ALL).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1084012

Frameshift mutations at coding mononucleotide repeats of the hRAD50 gene in gastrointestinal carcinomas with microsatellite instability

30 October 2018

1 reference

12 December 2020

Characterization of MSH2 and MLH1 mutations in Italian families with hereditary nonpolyposis colorectal cancer

1 reference

12 December 2020

The many interfaces of Mre11

1 reference

12 December 2020

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

1 reference

12 December 2020

10.1093/EMBO-REPORTS/KVF044

Identifiers

DOI

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29 July 2017

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29 July 2017

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