Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling (Q40331060)

19 September 2017

title

Notch 1 overexpression inhibits osteoblastogenesis by suppressing Wnt/beta-catenin but not bone morphogenetic protein signaling (English)

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19 September 2017

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1 reference

Ernesto Canalis

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author name string

Valerie Deregowski

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19 September 2017

Elisabetta Gazzerro

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19 September 2017

Leah Priest

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19 September 2017

Sheila Rydziel

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19 September 2017

Ernesto Canalis

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19 September 2017

language of work or name

English

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publication date

6 January 2006

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Journal of Biological Chemistry

19 September 2017

published in

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19 September 2017

volume

281

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19 September 2017

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19 September 2017

page(s)

6203-6210

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https://api.crossref.org/works/10.1074%2FJBC.M508370200

19 September 2017

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Expression patterns of Jagged, Delta1, Notch1, Notch2, and Notch3 genes identify ligand-receptor pairs that may function in neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Notch signaling: cell fate control and signal integration in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Notch 1 impairs osteoblastic cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Critical regulation of bone morphogenetic protein-induced osteoblastic differentiation by Delta1/Jagged1-activated Notch1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Marrow stromal stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Bone morphogenetic proteins, their antagonists, and the skeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Signal transduction of bone morphogenetic protein receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Smad1 recognition and activation by the ALK1 group of transforming growth factor-beta family receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Intracellular signaling of osteogenic protein-1 through Smad5 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Erk is essential for growth, differentiation, integrin expression, and cell function in human osteoblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Involvement of ERK in BMP-2 induced osteoblastic differentiation of mesenchymal progenitor cell line C3H10T1/2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Wnt signaling in osteoblasts and bone diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Signal transduction by the Wnt family of ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Propagation and localization of Wnt signaling.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M508370200

Mechanisms of Wnt signaling in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

BMP-2 controls alkaline phosphatase expression and osteoblast mineralization by a Wnt autocrine loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Interaction between Wingless and Notch signaling pathways mediated by dishevelled

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Where Notch and Wnt signaling meet. The presenilin hub

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Phosphorylation by glycogen synthase kinase-3 beta down-regulates Notch activity, a link for Notch and Wnt pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Glycogen synthase kinase-3beta modulates notch signaling and stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Presenilin affects arm/beta-catenin localization and function in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Notch and wingless regulate expression of cuticle patterning genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Cortisol regulates the expression of Notch in osteoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Effects of cortisol and bone morphogenetic protein-2 on stromal cell differentiation: correlation with CCAAT-enhancer binding protein expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Multiplex quantitative PCR using self-quenched primers labeled with a single fluorophore

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Effect of primary and secondary structure of oligodeoxyribonucleotides on the fluorescent properties of conjugated dyes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Skeletal overexpression of gremlin impairs bone formation and causes osteopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Wnt-1 induces growth, cytosolic beta-catenin, and Tcf/Lef transcriptional activation in Rat-1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Cortisol inhibits the differentiation and apoptosis of osteoblasts in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Bone morphogenetic protein-2 promotes osteoblast apoptosis through a Smad-independent, protein kinase C-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Signal transductions induced by bone morphogenetic protein-2 and transforming growth factor-beta in normal human osteoblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Association with the nuclear matrix and interaction with Groucho and RUNX proteins regulate the transcription repression activity of the basic helix loop helix factor Hes1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Sclerostin is an osteocyte-expressed negative regulator of bone formation, but not a classical BMP antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Osteogenic differentiation of the mesenchymal progenitor cells, Kusa is suppressed by Notch signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Dual roles for the Notch target gene Hes-1 in the differentiation of 3T3-L1 preadipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Control of endodermal endocrine development by Hes-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Regulation of Wnt signaling during adipogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Wnt signaling protects 3T3-L1 preadipocytes from apoptosis through induction of insulin-like growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Notch1 functions as a tumor suppressor in mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Glucocorticoids inhibit the transcriptional activity of LEF/TCF in differentiating osteoblasts in a glycogen synthase kinase-3beta-dependent and -independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Secreted frizzled-related protein 1 modulates glucocorticoid attenuation of osteogenic activities and bone mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

Notch signals control the fate of immature progenitor cells in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M508370200

21 January 2018

Identifiers

DOI

10.1074/JBC.M508370200

1 reference

19 September 2017

1 reference