Cyclic Disulfides as Functional Mimics of the Histone Deacetylase Inhibitor FK-228. (Q40326244)

19 September 2017

Cyclic Disulfides as Functional Mimics of the Histone Deacetylase Inhibitor FK-228. (English)

1 reference

19 September 2017

Jared R Mays

1 reference

19 September 2017

José A Restituyo

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19 September 2017

Rebeccah J Katzenberger

1 reference

19 September 2017

David A Wassarman

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19 September 2017

Scott R Rajski

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19 September 2017

1 June 2007

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full work available at URL

19 September 2017

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2084391

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published in

Tetrahedron Letters

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19 September 2017

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19 September 2017

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19 September 2017

4579-4583

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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

19 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Using Drosophila melanogaster to map human cancer pathways

22 September 2017

1 reference

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Emerging technologies for gene manipulation in Drosophila melanogaster

22 September 2017

1 reference

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Natural product based inhibitors of the thioredoxin-thioredoxin reductase system

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Deacetylase enzymes: biological functions and the use of small-molecule inhibitors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

HIF-1 and mechanisms of hypoxia sensing

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

HIF-1: using two hands to flip the angiogenic switch

22 September 2017

1 reference

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seco-Cyclothialidines: new concise synthesis, inhibitory activity toward bacterial and human DNA topoisomerases, and antibacterial properties

22 September 2017

1 reference

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Potent histone deacetylase inhibitors built from trichostatin A and cyclic tetrapeptide antibiotics including trapoxin

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Histone acetylation and cancer

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

A non-isotopic assay for histone deacetylase activity

22 September 2017

1 reference

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What's up and down with histone deacetylation and transcription?

22 September 2017

1 reference

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Amplification of hypoxia-inducible factor 1alpha gene in prostate cancer

22 September 2017

1 reference

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Understanding and controlling the cell cycle with natural products

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Histone acetylation and chromatin assembly: a single escort, multiple dances?

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Targeting tumors through the HIF system.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Nuclear histone acetylases and deacetylases and transcriptional regulation: HATs off to HDACs.

17 June 2018

1 reference

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Therapeutic attack of hypoxic cells of solid tumors: presidential address

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Cyclic tetrapeptides bearing a sulfhydryl group potently inhibit histone deacetylases

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Total Synthesis of the Depsipeptide FR-901375

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Inhibition of hypoxia-induced angiogenesis by FK228, a specific histone deacetylase inhibitor, via suppression of HIF-1alpha activity

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Suppression of tumor growth through disruption of hypoxia-inducible transcription

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Histone Deacetylase Inhibitors

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2084391

Total synthesis of spiruchostatin A, a potent histone deacetylase inhibitor

20 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18575573

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Angiogenesis and prostate cancer: identification of a molecular progression switch

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18575573

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Bioactivation as a model for drug design bioreductive alkylation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18575573

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.TETLET.2007.04.123

1 reference

19 September 2017

1 reference

19 September 2017

PubMed publication ID

18575573

1 reference