Tonic and phasic guanidinium toxin-block of skeletal muscle Na channels expressed in Mammalian cells. (Q40235445)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12719231%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

title

Tonic and phasic guanidinium toxin-block of skeletal muscle Na channels expressed in Mammalian cells (English)

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3 November 2019

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3 November 2019

Oscar Moran

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3 November 2019

Franco Conti

series ordinal

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3 November 2019

language of work or name

English

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publication date

1 May 2003

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3 November 2019

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3 November 2019

volume

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3 November 2019

issue

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3 November 2019

page(s)

2999-3006

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Energetic localization of saxitoxin in its channel binding site.

3 November 2019

cites work

1 reference

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Modulation of sodium current in mammalian cells by an epilepsy-correlated beta 1-subunit mutation

22 September 2017

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Specific neosaxitoxin interactions with the Na+ channel outer vestibule determined by mutant cycle analysis.

22 September 2017

1 reference

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Tonic and phasic tetrodotoxin block of sodium channels with point mutations in the outer pore region

22 September 2017

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Differences in saxitoxin and tetrodotoxin binding revealed by mutagenesis of the Na+ channel outer vestibule.

22 September 2017

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Use dependence of tetrodotoxin block of sodium channels: a revival of the trapped-ion mechanism

22 September 2017

1 reference

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Impaired slow inactivation in mutant sodium channels

22 September 2017

1 reference

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Specificity for block by saxitoxin and divalent cations at a residue which determines sensitivity of sodium channel subtypes to guanidinium toxins

22 September 2017

1 reference

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Post-repolarization block of cardiac sodium channels by saxitoxin

22 September 2017

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A structural model of the tetrodotoxin and saxitoxin binding site of the Na+ channel

22 September 2017

1 reference

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Post-repolarization block of cloned sodium channels by saxitoxin: the contribution of pore-region amino acids

22 September 2017

1 reference

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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

22 September 2017

1 reference

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Chemicals as tools in the study of excitable membranes

22 September 2017

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The receptor for tetrodotoxin and saxitoxin. A structural hypothesis

22 September 2017

1 reference

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The binding of saxitoxin and tetrodotoxin to excitable tissue

22 September 2017

1 reference

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Saxitoxin binding to the mammalian sodium channel. Competition by monovalent and divalent cations

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

Voltage-dependent block by tetrodotoxin of the sodium channel in rabbit cardiac Purkinje fibers

22 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

Use dependence of sodium current inhibition by tetrodotoxin in rat cardiac muscle: influence of channel state

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

The microI skeletal muscle sodium channel: mutation E403Q eliminates sensitivity to tetrodotoxin but not to mu-conotoxins GIIIA and GIIIB.

25 September 2017

1 reference

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Primary structure and functional expression of a mammalian skeletal muscle sodium channel

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

Use-dependent block of sodium channels in frog myelinated nerve by tetrodotoxin and saxitoxin at negative holding potentials.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

Single point mutations of the sodium channel drastically reduce the pore permeability without preventing its gating

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

A voltage-dependent gating transition induces use-dependent block by tetrodotoxin of rat IIA sodium channels expressed in Xenopus oocytes.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

A mutant of TTX-resistant cardiac sodium channels with TTX-sensitive properties

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

Na channel kinetics remain stable during perforated-patch recordings.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

Molecular basis for pharmacological differences between brain and cardiac sodium channels

15 June 2018

1 reference

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Molecular localization of an ion-binding site within the pore of mammalian sodium channels

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

Calcium channel characteristics conferred on the sodium channel by single mutations

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

Site-directed mutagenesis of the putative pore region of the rat IIA sodium channel.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1302862

The permeability of the sodium channel to organic cations in myelinated nerve

20 August 2018

1 reference

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Structure-activity relations of tetrodotoxin, saxitoxin, and analogues.

20 August 2018

1 reference

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KcsA crystal structure as framework for a molecular model of the Na(+) channel pore

20 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2970026-5

Functional properties of sodium channels do not depend on the cytoskeleton integrity

7 January 2021

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2970026-5

Use- and voltage-dependent block of the sodium channel by saxitoxin

7 January 2021

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FS0006-3495%2803%2970026-5

10.1016/S0006-3495(03)70026-5

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12719231%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12719231%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

12719231

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12719231%20AND%20SRC:MED&resulttype=core&format=json