Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis (Q40102582)

17 September 2017

title

Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis (English)

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17 September 2017

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17 September 2017

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17 September 2017

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17 September 2017

Zimmermann D

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17 September 2017

Heinzel T

series ordinal

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17 September 2017

language of work or name

English

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publication date

23 July 2007

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17 September 2017

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17 September 2017

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17 September 2017

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17 September 2017

page(s)

732-740

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Are p27 and p21 cytoplasmic oncoproteins?

17 September 2017

cites work

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Inducible p27(Kip1) expression inhibits proliferation of K562 cells and protects against apoptosis induction by proteasome inhibitors

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p27Kip1 induces drug resistance by preventing apoptosis upstream of cytochrome c release and procaspase-3 activation in leukemic cells.

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Inhibitors of histone deacetylase arrest cell cycle and induce apoptosis in cervical carcinoma cells circumventing human papillomavirus oncogene expression

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Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

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Depsipeptide (FR901228) inhibits proliferation and induces apoptosis in primary and metastatic human uveal melanoma cell lines

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The Survivin-Crm1 interaction is essential for chromosomal passenger complex localization and function

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Update on therapy for melanoma: opportunities for patient selection and overcoming tumor resistance

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Acetylation: a regulatory modification to rival phosphorylation?

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Acetylation of Stat1 modulates NF-kappaB activity

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Histone deacetylase as a therapeutic target

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The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2

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The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination with all-trans retinoic acid in patients with acute myeloid leukemia

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Drug resistance in melanoma: new perspectives.

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Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

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The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells.

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Molecular remission following high-dose hydroxyurea and fludarabine plus cytarabine in a patient with simultaneous acute myeloid leukemia and low-grade lymphoma

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Abrogation of p21 expression by flavopiridol enhances depsipeptide-mediated apoptosis in malignant pleural mesothelioma cells

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Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

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Differentiation of human malignant melanoma cells that escape apoptosis after treatment with 9-nitrocamptothecin in vitro

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Differential modulation of paclitaxel-mediated apoptosis by p21Waf1 and p27Kip1

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Hydroxyurea for treatment of unresectable and recurrent meningiomas. I. Inhibition of primary human meningioma cells in culture and in meningioma transplants by induction of the apoptotic pathway

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Hydroxyurea for treatment of unresectable and recurrent meningiomas. II. Decrease in the size of meningiomas in patients treated with hydroxyurea

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Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation

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Impact of the cyclin-dependent kinase inhibitor p27Kip1 on resistance of tumor cells to anticancer agents

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Procaspase 3/p21 complex formation to resist fas-mediated cell death is initiated as a result of the phosphorylation of p21 by protein kinase A

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Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21

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The Enzyme Ribonucleotide Reductase: Target for Antitumor and Anti-HIV Therapy

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Use of hydroxyurea to alter drug resistance of human tumor cells

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Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis

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Identifiers

DOI

10.1038/SJ.ONC.1210677

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Dimensions Publication ID

17 September 2017

1046408758

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