HIV-1 TAT inhibits microglial phagocytosis of Abeta peptide. (Q40048514)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784813%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

title

HIV-1 TAT inhibits microglial phagocytosis of Abeta peptide (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784813%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

0 references

1 reference

1 reference

Brian Giunta

1 reference

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14 January 2020

Yuyan Zhou

1 reference

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14 January 2020

Huayan Hou

1 reference

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14 January 2020

Elona Rrapo

1 reference

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14 January 2020

Francisco Fernandez

1 reference

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14 January 2020

Jun Tan

1 reference

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14 January 2020

publication date

1 January 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784813%20AND%20SRC:MED&resulttype=core&format=json

International Journal of Clinical and Experimental Pathology

14 January 2020

published in

1 reference

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14 January 2020

volume

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14 January 2020

issue

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14 January 2020

page(s)

260-275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784813%20AND%20SRC:MED&resulttype=core&format=json

The coming problem of HIV-associated Alzheimer's disease

14 January 2020

cites work

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Brain deposition of beta-amyloid is a common pathologic feature in HIV positive patients

22 September 2017

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Green tea polyphenol (-)-epigallocatechin gallate blocks epithelial barrier dysfunction provoked by IFN-gamma but not by IL-4.

22 September 2017

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ApoE and Abeta1-42 interactions: effects of isoform and conformation on structure and function

22 September 2017

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Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes

22 September 2017

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Microglia are activated to become competent antigen presenting and effector cells in the inflammatory environment of the Theiler's virus model of multiple sclerosis

22 September 2017

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Immune Restoration Inflammatory Syndromes: The Dark Side of Successful Antiretroviral Treatment.

22 September 2017

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Neuropathologies in Transgenic Mice Expressing Human Immunodeficiency Virus Type 1 Tat Protein under the Regulation of the Astrocyte-Specific Glial Fibrillary Acidic Protein Promoter and Doxycycline

22 September 2017

1 reference

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HIV-1-associated dementia: a metabolic encephalopathy perpetrated by virus-infected and immune-competent mononuclear phagocytes.

22 September 2017

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Microglia and inflammatory mechanisms in the clearance of amyloid beta peptide

22 September 2017

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Temperature-sensitive mutants of the exosome subunit Rrp43p show a deficiency in mRNA degradation and no longer interact with the exosome.

22 September 2017

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HIV-1-associated dementia: a basic science and clinical perspective

22 September 2017

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Phagocytotic removal of apoptotic, inflammatory lymphocytes in the central nervous system by microglia and its functional implications

22 September 2017

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The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis

22 September 2017

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Kinetics of a gamma interferon response: expression and assembly of CIITA promoter IV and inhibition by methylation

22 September 2017

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Macrophages, chemokines and neuronal injury in HIV-1-associated dementia

22 September 2017

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22 September 2017

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22 September 2017

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22 September 2017

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Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands

22 September 2017

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22 September 2017

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Mononuclear phagocytes mediate blood-brain barrier compromise and neuronal injury during HIV-1-associated dementia.

22 September 2017

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Regulation of STAT1 nuclear export by Jak1

22 September 2017

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Role of macrophage activation in the pathogenesis of Alzheimer's disease and human immunodeficiency virus type 1-associated dementia

22 September 2017

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CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex

22 September 2017

1 reference

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Common binding sites for beta-amyloid fibrils and fibroblast growth factor-2 in heparan sulfate from human cerebral cortex

22 September 2017

1 reference

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Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta

22 September 2017

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Prevalence of Alzheimer plaques in AIDS.

22 September 2017

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HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region

22 September 2017

1 reference

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Expression of MHC class II molecules in different cellular and functional compartments is controlled by differential usage of multiple promoters of the transactivator CIITA.

22 September 2017

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Microglia: a sensor for pathological events in the CNS

22 September 2017

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Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation

22 September 2017

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Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

22 September 2017

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Secretion-capture role for apolipoprotein E in remnant lipoprotein metabolism involving cell surface heparan sulfate proteoglycans

22 September 2017

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Isoform-specific binding of apolipoprotein E to beta-amyloid

22 September 2017

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Interferon-activated signal transduction to the nucleus

22 September 2017

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Differential binding of vascular cell-derived proteoglycans (perlecan, biglycan, decorin, and versican) to the beta-amyloid protein of Alzheimer's disease

22 September 2017

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Apolipoprotein E: impact of cytoskeletal stability in neurons and the relationship to Alzheimer's disease.

22 September 2017

1 reference

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Role of heparan sulfate proteoglycans in the binding and uptake of apolipoprotein E-enriched remnant lipoproteins by cultured cells

22 September 2017

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Stable expression and secretion of apolipoproteins E3 and E4 in mouse neuroblastoma cells produces differential effects on neurite outgrowth

22 September 2017

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Low density lipoprotein receptor-related protein mediates apolipoprotein E-dependent neurite outgrowth in a central nervous system-derived neuronal cell line

22 September 2017

1 reference

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Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

22 September 2017

1 reference

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Risk factors associated with senile dementia of the Alzheimer's type

22 September 2017

1 reference

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Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1.

22 September 2017

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Transcellular activation of the human immunodeficiency virus type 1 long terminal repeat in cocultured lymphocytes

22 September 2017

1 reference

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HIV-1 in postmortem brain tissue from patients with AIDS: a comparison of different detection techniques

22 September 2017

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Accelerated phagocytosis of amyloid-beta by mouse and human microglia overexpressing the macrophage colony-stimulating factor receptor

22 September 2017

1 reference

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Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease

25 September 2017

1 reference

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DNA binding of in vitro activated Stat1 alpha, Stat1 beta and truncated Stat1: interaction between NH2-terminal domains stabilizes binding of two dimers to tandem DNA sites

25 September 2017

1 reference

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Dementia in AIDS patients: incidence and risk factors. Multicenter AIDS Cohort Study.

25 September 2017

1 reference

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Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.

25 September 2017

1 reference

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Apolipoprotein E-containing high density lipoprotein promotes neurite outgrowth and is a ligand for the low density lipoprotein receptor-related protein

25 September 2017

1 reference

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The inhibitory effect of apolipoprotein E4 on neurite outgrowth is associated with microtubule depolymerization

25 September 2017

1 reference

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Simvastatin inhibits interferon-gamma-induced MHC class II up-regulation in cultured astrocytes

25 September 2017

1 reference

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Neuropathologic and neuroinflammatory activities of HIV-1-infected human astrocytes in murine brain

15 June 2018

1 reference

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Epidermal caspase-3 cleavage associated with interferon-gamma-expressing lymphocytes in acute atopic dermatitis lesions

15 June 2018

1 reference

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Safety studies on epigallocatechin gallate (EGCG) preparations. Part 1: genotoxicity

15 June 2018

1 reference

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Vasculopathy and amyloid beta reactivity in brains of patients with acquired immune deficiency (AIDS).

15 June 2018

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Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

15 June 2018

1 reference

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Lipopolysaccharide-induced IL-12 expression in the central nervous system and cultured astrocytes and microglia

15 June 2018

1 reference

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Binding of secreted human neuroblastoma proteoglycans to the Alzheimer's amyloid A4 peptide.

15 June 2018

1 reference

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Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E.

15 June 2018

1 reference

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Norepinephrine inhibits gamma-interferon-induced MHC class II (Ia) antigen expression on cultured brain astrocytes.

15 June 2018

1 reference

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Amyloidosis in association with human immunodeficiency virus infection

15 June 2018

1 reference

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Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils

15 June 2018

1 reference

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Functional synergy between CD40 ligand and HIV-1 Tat contributes to inflammation: implications in HIV type 1 dementia.

15 June 2018

1 reference

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(-)-Epigallocatechin gallate suppresses indoleamine 2,3-dioxygenase expression in murine dendritic cells: evidences for the COX-2 and STAT1 as potential targets.

20 August 2018

1 reference

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Pro-inflammatory conditions promote neuronal damage mediated by Amyloid Precursor Protein and decrease its phagocytosis and degradation by microglial cells in culture

20 August 2018

1 reference

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Tat peptides inhibit neprilysin

20 August 2018

1 reference

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Suppressor of cytokine signaling 1 expression protects oligodendrocytes from the deleterious effects of interferon-gamma.

20 August 2018

1 reference

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ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Safety studies on epigallocatechin gallate (EGCG) preparations. Part 2: dermal, acute and short-term toxicity studies

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

CSF amyloid beta42 and tau levels correlate with AIDS dementia complex

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Dementia and Alzheimer's disease incidence in relationship to cardiovascular disease in the Cardiovascular Health Study cohort.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

CD40 signaling regulates innate and adaptive activation of microglia in response to amyloid beta-peptide.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Tat and amyloid: multiple interactions

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

HIV-1 Tat inhibits neprilysin and elevates amyloid beta

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

The prevalence of dementia in 95 year olds.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Plasma-kinetic characteristics of purified and isolated green tea catechin epigallocatechin gallate (EGCG) after 10 days repeated dosing in healthy volunteers

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Inflammatory changes and breakdown of microvascular integrity in early human immunodeficiency virus dementia

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Galantamine and nicotine have a synergistic effect on inhibition of microglial activation induced by HIV-1 gp120.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

MHC class II expression is differentially regulated in plasmacytoid and conventional dendritic cells.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Uptake of Abeta 1-40- and Abeta 1-42-coated yeast by microglial cells: a role for LRP.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Elevated expression of IFN-gamma in the HIV-1 infected brain

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Synaptic transport of human immunodeficiency virus-Tat protein causes neurotoxicity and gliosis in rat brain.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

CD45-positive cells of the retina and their responsiveness to in vivo and in vitro treatment with IFN-gamma or anti-CD40.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Human immunodeficiency virus type 1 (HIV-1) induces activation of multiple STATs in CD4+ cells of lymphocyte or monocyte/macrophage lineages

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

STAT1 is activated in neurons after ischemia and contributes to ischemic brain injury

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Identification of a common sphingolipid-binding domain in Alzheimer, prion, and HIV-1 proteins.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Alpha2-macroglobulin enhances the clearance of endogenous soluble beta-amyloid peptide via low-density lipoprotein receptor-related protein in cortical neurons

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

CD40-CD154 interaction and IFN-gamma are required for IL-12 but not prostaglandin E2 secretion by microglia during antigen presentation to Th1 cells.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

HIV-1 protein Tat induces apoptosis of hippocampal neurons by a mechanism involving caspase activation, calcium overload, and oxidative stress

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Microglia are more efficient than astrocytes in antigen processing and in Th1 but not Th2 cell activation.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

HIV-1 Tat alters normal organization of neurons and astrocytes in primary rodent brain cell cultures: RGD sequence dependence

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Influence of the human immunodeficiency virus type 1 Tat protein on the proliferation and differentiation of PC12 rat pheochromocytoma cells.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Glial cytokines as neuropathogenic factors in HIV infection: pathogenic similarities to Alzheimer's disease.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Differential effects of apolipoproteins E3 and E4 on neuronal growth in vitro

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Proteoglycan-mediated inhibition of A beta proteolysis. A potential cause of senile plaque accumulation.

20 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2480563

Apolipoprotein E: binding to soluble Alzheimer's beta-amyloid

20 August 2018

1 reference

12 December 2020

Binding of vascular heparan sulfate proteoglycan to Alzheimer's amyloid precursor protein is mediated in part by the N-terminal region of A4 peptide

1 reference

12 December 2020

Review: neuronal injury in HIV infection

1 reference

12 December 2020

HIV-associated cognitive impairment before and after the advent of combination therapy

1 reference

12 December 2020

Differential effects of beta and gamma interferons on expression of major histocompatibility complex antigens and intercellular adhesion molecule-1 in cultured fetal human astrocytes

1 reference

12 December 2020

HIV-infected subjects with the E4 allele for APOE have excess dementia and peripheral neuropathy

1 reference

12 December 2020

CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway

1 reference

12 December 2020

Apolipoprotein E promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner

1 reference

12 December 2020

pH-dependent binding of synthetic beta-amyloid peptides to glycosaminoglycans

1 reference

12 December 2020

Accumulation of beta-amyloid precursor protein in axons correlates with CNS expression of SIV gp41

1 reference

12 December 2020

Apolipoprotein E polymorphism and atherosclerosis

1 reference

12 December 2020

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784813%20AND%20SRC:MED&resulttype=core&format=json

14 January 2020

PubMed publication ID

18784813

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18784813%20AND%20SRC:MED&resulttype=core&format=json