Cholesterol potentiates beta-amyloid-induced toxicity in human neuroblastoma cells: involvement of oxidative stress (Q40010770)

16 September 2017

title

Cholesterol potentiates beta-amyloid-induced toxicity in human neuroblastoma cells: involvement of oxidative stress (English)

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16 September 2017

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16 September 2017

Patricia Ferrera

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16 September 2017

Octavio Mercado-Gómez

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16 September 2017

Martín Silva-Aguilar

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16 September 2017

Clorinda Arias

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16 September 2017

publication date

21 February 2008

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16 September 2017

published in

Neurochemical Research

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16 September 2017

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16 September 2017

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16 September 2017

page(s)

1509-1517

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Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic APP(SW) mice

16 September 2017

cites work

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Crossref

https://api.crossref.org/works/10.1007%2FS11064-008-9623-Y

The effect of simvastatin treatment on the amyloid precursor protein and brain cholesterol metabolism in patients with Alzheimer's disease

21 January 2018

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12 December 2020

Statins induce differentiation and cell death in neurons and astroglia

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12 December 2020

Clinical and pathological correlates of apolipoprotein E ?4 in Alzheimer's disease

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12 December 2020

24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia

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12 December 2020

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

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12 December 2020

Genetic influences on age-related change in total cholesterol, low density lipoprotein-cholesterol, and triglyceride levels: longitudinal apolipoprotein E genotype effects

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12 December 2020

Increased antioxidant enzyme activity in amyloid beta protein-resistant cells

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12 December 2020

Statins and the risk of dementia

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12 December 2020

Involvement of Oxidative Stress on the Impairment of Energy Metabolism Induced by Aβ Peptides on PC12 Cells: Protection by Antioxidants

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12 December 2020

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

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12 December 2020

Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham Study

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12 December 2020

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

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12 December 2020

Role of oxidative stress on beta-amyloid neurotoxicity elicited during impairment of energy metabolism in the hippocampus: protection by antioxidants

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12 December 2020

Microcystin-LR and nodularin induce intracellular glutathione alteration, reactive oxygen species production and lipid peroxidation in primary cultured rat hepatocytes

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12 December 2020

Lovastatin induces growth inhibition and apoptosis in human malignant glioma cells

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12 December 2020

Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers.

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12 December 2020

HMG CoA reductase inhibitors reduce ischemic brain injury of Wistar rats through decreasing oxidative stress on neurons

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12 December 2020

Model studies of cholesterol and ascorbate oxidation by copper complexes: relevance to Alzheimer's disease beta-amyloid metallochemistry

1 reference

12 December 2020

Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta

1 reference

12 December 2020

A novel function of monomeric amyloid beta-protein serving as an antioxidant molecule against metal-induced oxidative damage

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12 December 2020

3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors protect cortical neurons from excitotoxicity.

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12 December 2020

Oxidative stress: the old enemy in Alzheimer's disease pathophysiology

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12 December 2020

Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review

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12 December 2020

High cholesterol content in neurons increases BACE, beta-amyloid, and phosphorylated tau levels in rabbit hippocampus

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12 December 2020

The metallobiology of Alzheimer's disease

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12 December 2020

Lovastatin induces apoptosis of spontaneously immortalized rat brain neuroblasts: involvement of nonsterol isoprenoid biosynthesis inhibition

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12 December 2020

Lipid metabolism in cognitive decline and dementia

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12 December 2020

Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches

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12 December 2020

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

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12 December 2020

Antioxidants as a potential therapy against age-related neurodegenerative diseases: amyloid Beta toxicity and Alzheimer's disease

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12 December 2020

Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway

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12 December 2020

RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

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12 December 2020

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

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12 December 2020

The levels of soluble amyloid beta in different high density lipoprotein subfractions distinguish Alzheimer's and normal aging cerebrospinal fluid: implication for brain cholesterol pathology?

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12 December 2020

Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls

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12 December 2020

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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12 December 2020

Fluorescence probes used for detection of reactive oxygen species

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12 December 2020

Altered levels of plasma 24S- and 27-hydroxycholesterol in demented patients

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12 December 2020

beta-Amyloid peptide fragment 25-35 potentiates the calcium-dependent release of excitatory amino acids from depolarized hippocampal slices.

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12 December 2020

Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol

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12 December 2020

Co-localization of cholesterol, apolipoprotein E and fibrillar Abeta in amyloid plaques

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12 December 2020

Redox-active iron mediates amyloid-beta toxicity

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12 December 2020

Filipin-positive, oil red O-negative particles in atherosclerotic lesions induced by cholesterol feeding.

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12 December 2020

Red mold rice ameliorates impairment of memory and learning ability in intracerebroventricular amyloid beta-infused rat by repressing amyloid beta accumulation

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12 December 2020

beta-Amyloid peptide induces ultrastructural changes in synaptosomes and potentiates mitochondrial dysfunction in the presence of ryanodine

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12 December 2020

Redox proteomics identification of oxidatively modified brain proteins in Alzheimer's disease and mild cognitive impairment: insights into the progression of this dementing disorder.

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12 December 2020

Characterization of human neuroblastoma cell lines established before and after therapy.

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12 December 2020

Alzheimer disease beta-amyloid activity mimics cholesterol oxidase

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12 December 2020

Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons.

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12 December 2020

beta-Amyloid neurotoxicity is exacerbated during glycolysis inhibition and mitochondrial impairment in the rat hippocampus in vivo and in isolated nerve terminals: implications for Alzheimer's disease

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12 December 2020

Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide.

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12 December 2020

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

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12 December 2020

Oxysterols, cholesterol homeostasis, and Alzheimer disease

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12 December 2020

A fluid connection: cholesterol and Abeta

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12 December 2020

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

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12 December 2020

NADPH oxidase activity in preeclampsia with immortalized lymphoblasts used as models

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12 December 2020

Statin-induced heme oxygenase-1 increases NF-kappaB activation and oxygen radical production in cultured neuronal cells exposed to lipopolysaccharide

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12 December 2020

10.1007/S11064-008-9623-Y

Identifiers

DOI

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Dimensions Publication ID

16 September 2017

1028590795

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