3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors protect cortical neurons from excitotoxicity. (Q44681111)

PubMed publication ID

14657168

5 December 2017

title

3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors protect cortical neurons from excitotoxicity (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741057&resulttype=core&format=json

12 May 2020

1 reference

Anna Zacco

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741057&resulttype=core&format=json

12 May 2020

James Togo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741057&resulttype=core&format=json

12 May 2020

Katherine Spence

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741057&resulttype=core&format=json

12 May 2020

Amanda Ellis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741057&resulttype=core&format=json

12 May 2020

Darlene Lloyd

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741057&resulttype=core&format=json

12 May 2020

Steve Furlong

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741057&resulttype=core&format=json

12 May 2020

Timothy Piser

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741057&resulttype=core&format=json

12 May 2020

language of work or name

English

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publication date

1 December 2003

1 reference

PubMed publication ID

14657168

5 December 2017

published in

Journal of Neuroscience

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12 May 2020

volume

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12 May 2020

issue

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12 May 2020

page(s)

11104-11111

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741057&resulttype=core&format=json

Scrapie-infected mice and PrP knockout mice share abnormal localization and activity of neuronal nitric oxide synthase

12 May 2020

cites work

1 reference

12 December 2020

Inhibition of cholesterol production but not of nonsterol isoprenoid products induces neuronal cell death

1 reference

12 December 2020

Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein

1 reference

12 December 2020

PSD-95 assembles a ternary complex with the N-methyl-D-aspartic acid receptor and a bivalent neuronal NO synthase PDZ domain

1 reference

12 December 2020

Efficacy of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors for prevention of stroke

1 reference

12 December 2020

Differential Targeting of Shaker-like Potassium Channels to Lipid Rafts

1 reference

12 December 2020

Geranylgeranyl-pyrophosphate, an isoprenoid of mevalonate cascade, is a critical compound for rat primary cultured cortical neurons to protect the cell death induced by 3-hydroxy-3-methylglutaryl-CoA reductase inhibition.

1 reference

12 December 2020

Atorvastatin upregulates type III nitric oxide synthase in thrombocytes, decreases platelet activation, and protects from cerebral ischemia in normocholesterolemic mice

1 reference

12 December 2020

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

1 reference

12 December 2020

Statins and the risk of dementia

1 reference

12 December 2020

Preclinical and clinical pharmacology of Rosuvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor

1 reference

12 December 2020

Mevastatin, an HMG-CoA reductase inhibitor, reduces stroke damage and upregulates endothelial nitric oxide synthase in mice

1 reference

12 December 2020

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

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12 December 2020

Rapid effects on vascular function after initiation and withdrawal of atorvastatin in healthy, normocholesterolemic men.

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12 December 2020

Molecular mechanisms of glutamate receptor-mediated excitotoxic neuronal cell death

1 reference

12 December 2020

Rosuvastatin, a new HMG-CoA reductase inhibitor, upregulates endothelial nitric oxide synthase and protects from ischemic stroke in mice

1 reference

12 December 2020

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

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12 December 2020

Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial

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12 December 2020

Effects of statins on human cerebral cholesterol metabolism and secretion of Alzheimer amyloid peptide

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12 December 2020

Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions

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12 December 2020

Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial

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12 December 2020

Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

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12 December 2020

Differential inhibitory effects of lovastatin on protein isoprenylation and sterol synthesis

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12 December 2020

Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

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12 December 2020

Alteration of the myometrial plasma membrane cholesterol content with beta-cyclodextrin modulates the binding affinity of the oxytocin receptor

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12 December 2020

Cellular cholesterol efflux mediated by cyclodextrins

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12 December 2020

Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures

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12 December 2020

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1 reference

12 December 2020

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

1 reference

12 December 2020

N-terminal palmitoylation of PSD-95 regulates association with cell membranes and interaction with K+ channel Kv1.4.

1 reference

12 December 2020

Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors

1 reference

12 December 2020

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

1 reference

12 December 2020

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

1 reference

12 December 2020

Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase

1 reference

12 December 2020

Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels

1 reference

12 December 2020

The N-terminal PDZ-containing region of postsynaptic density-95 mediates association with caveolar-like lipid domains

1 reference

12 December 2020

10.1523/JNEUROSCI.23-35-11104.2003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741057&resulttype=core&format=json

12 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741057&resulttype=core&format=json

12 May 2020

PubMed publication ID

14657168

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741057&resulttype=core&format=json