LINGO-1 antibody ameliorates myelin impairment and spatial memory deficits in the early stage of 5XFAD mice. (Q48503062)

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scientific article published on 9 February 2018

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English	LINGO-1 antibody ameliorates myelin impairment and spatial memory deficits in the early stage of 5XFAD mice.	scientific article published on 9 February 2018

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scholarly article

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Europe PubMed Central

PMC publication ID

6489849

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29427384%20AND%20SRC:MED&resulttype=core&format=json

retrieved

15 March 2020

title

LINGO-1 antibody ameliorates myelin impairment and spatial memory deficits in the early stage of 5XFAD mice (English)

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stated in

Europe PubMed Central

PMC publication ID

6489849

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29427384%20AND%20SRC:MED&resulttype=core&format=json

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15 March 2020

main subject

spatial memory

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author

Li-Hua Gu

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3

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Europe PubMed Central

PMC publication ID

6489849

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29427384%20AND%20SRC:MED&resulttype=core&format=json

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15 March 2020

Feng Bai

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6

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6489849

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29427384%20AND%20SRC:MED&resulttype=core&format=json

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15 March 2020

Zhi-Jun Zhang

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10

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PMC publication ID

6489849

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29427384%20AND%20SRC:MED&resulttype=core&format=json

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15 March 2020

author name string

Di Wu

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1

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PMC publication ID

6489849

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29427384%20AND%20SRC:MED&resulttype=core&format=json

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Xiang Tang

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2

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PMC publication ID

6489849

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15 March 2020

Xiao-Li Li

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4

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6489849

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15 March 2020

Xin-Yang Qi

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5

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6489849

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15 March 2020

Xiao-Chun Chen

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7

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6489849

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15 March 2020

Jian-Zhi Wang

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8

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6489849

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15 March 2020

Qing-Guo Ren

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9

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PMC publication ID

6489849

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15 March 2020

publication date

9 February 2018

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6489849

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15 March 2020

published in

CNS Neuroscience & Therapeutics

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Europe PubMed Central

PMC publication ID

6489849

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29427384%20AND%20SRC:MED&resulttype=core&format=json

retrieved

15 March 2020

volume

24

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Europe PubMed Central

PMC publication ID

6489849

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29427384%20AND%20SRC:MED&resulttype=core&format=json

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15 March 2020

issue

5

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Europe PubMed Central

PMC publication ID

6489849

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29427384%20AND%20SRC:MED&resulttype=core&format=json

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15 March 2020

page(s)

381-393

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6489849

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15 March 2020

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ImageJ

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11 June 2022

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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6489849/fullTextXML

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cites work

Immunoblot detection of antibodies to myelin basic protein in Alzheimer's disease patients

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination in human cerebrospinal fluid of glial fibrillary acidic protein, S-100 and myelin basic protein as indices of non-specific or specific central nervous tissue pathology

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

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inferred from PubMed ID database lookup

2',3'-cyclic nucleotide-3'-phosphodiesterase activity as an index of myelin in the post-mortem brains of patients with Alzheimer's disease

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

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Decreased myelin lipids in Alzheimer's disease and vascular dementia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

X-ray diffraction evidence for myelin disorder in brain from humans with Alzheimer's disease

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased brain levels of 2',3'-cyclic nucleotide-3'-phosphodiesterase in Down syndrome and Alzheimer's disease

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased A beta peptides and reduced cholesterol and myelin proteins characterize white matter degeneration in Alzheimer's disease

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

retrieved

12 December 2020

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inferred from PubMed ID database lookup

LINGO-1 is a component of the Nogo-66 receptor/p75 signaling complex

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusion tensor imaging detects age-dependent white matter changes in a transgenic mouse model with amyloid deposition

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astroglial expression of ceramide in Alzheimer's disease brains: a role during neuronal apoptosis.

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RhoA, RhoB, RhoC, Rac1, Cdc42, and Tc10 mRNA levels in spinal cord, sensory ganglia, and corticospinal tract neurons and long-lasting specific changes following spinal cord injury

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LINGO-1 negatively regulates myelination by oligodendrocytes

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal white matter integrity in healthy apolipoprotein E epsilon4 carriers

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E genotype and age-related myelin breakdown in healthy individuals: implications for cognitive decline and dementia

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

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The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LINGO-1 antagonist promotes functional recovery and axonal sprouting after spinal cord injury

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathology

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional pattern of white matter microstructural changes in normal aging, MCI, and AD.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Focal demyelination in Alzheimer's disease and transgenic mouse models.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in multiple measures of white matter integrity in normal women at high risk for Alzheimer's disease

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

White matter is altered with parental family history of Alzheimer's disease

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoantibodies against amyloid and glial-derived antigens are increased in serum and cerebrospinal fluid of Lewy body-associated dementias

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

White matter integrity and vulnerability to Alzheimer's disease: preliminary findings and future directions

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cerebrospinal fluid matrix metalloproteinases and tissue inhibitor of metalloproteinases in combination with subcortical and cortical biomarkers in vascular dementia and Alzheimer's disease

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutralization of LINGO-1 during in vitro differentiation of neural stem cells results in proliferation of immature neurons

1 reference

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/29427384

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CNP and DPYSL2 mRNA expression and promoter methylation levels in brain of Alzheimer's disease patients

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased hippocampal NgR1 signaling machinery in aged rats with deficits of spatial cognition.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of NgR1-antagonizing proteins decreases with aging and cognitive decline in rat hippocampus

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

White matter abnormalities associated with Alzheimer's disease and mild cognitive impairment: a critical review of MRI studies

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperphosphorylation of Tau at Ser396 occurs in the much earlier stage than appearance of learning and memory disorders in 5XFAD mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Strategies for myelin regeneration: lessons learned from development

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

LINGO-1 antibody ameliorates myelin impairment and spatial memory deficits in experimental autoimmune encephalomyelitis mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myelin injury induces axonal transport impairment but not AD-like pathology in the hippocampus of cuprizone-fed mice

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/29427384

retrieved

12 December 2020

based on heuristic

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Identifiers

DOI

10.1111/CNS.12809

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stated in

Europe PubMed Central

PMC publication ID

6489849

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29427384%20AND%20SRC:MED&resulttype=core&format=json

retrieved

15 March 2020

PMC publication ID

6489849

1 reference

stated in

Europe PubMed Central

PMC publication ID

6489849

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29427384%20AND%20SRC:MED&resulttype=core&format=json

retrieved

15 March 2020

PubMed publication ID

29427384

1 reference

stated in

Europe PubMed Central

PMC publication ID

6489849

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29427384%20AND%20SRC:MED&resulttype=core&format=json

retrieved

15 March 2020

 

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