Caspase-9 inhibition after focal cerebral ischemia improves outcome following reversible focal ischemia (Q48481017)

11 February 2018

title

Caspase-9 inhibition after focal cerebral ischemia improves outcome following reversible focal ischemia (English)

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11 February 2018

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Graham Mouw

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11 February 2018

Jennifer L Zechel

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11 February 2018

Yifang Zhou

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11 February 2018

W David Lust

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11 February 2018

Warren R Selman

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11 February 2018

Robert A Ratcheson

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11 February 2018

publication date

1 September 2002

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11 February 2018

published in

Metabolic Brain Disease

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11 February 2018

volume

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11 February 2018

issue

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11 February 2018

page(s)

143-151

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11 February 2018

Prolonged therapeutic window for ischemic brain damage caused by delayed caspase activation

cites work

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12 December 2020

Intact, injured, necrotic and apoptotic cells after focal cerebral ischemia in the rat.

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12 December 2020

All along the watchtower: on the regulation of apoptosis regulators.

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12 December 2020

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

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12 December 2020

WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation

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12 December 2020

Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage

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12 December 2020

Diva, a Bcl-2 homologue that binds directly to Apaf-1 and induces BH3-independent cell death

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12 December 2020

Caspase inhibitors reduce neuronal injury after focal but not global cerebral ischemia in rats

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12 December 2020

Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury

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12 December 2020

Conversion of Bcl-2 to a Bax-like Death Effector by Caspases

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12 December 2020

Infarct measurement methodology

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12 December 2020

Caspases induce cytochrome c release from mitochondria by activating cytosolic factors

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12 December 2020

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

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12 December 2020

Cleavage of Bcl-2 is an early event in chemotherapy-induced apoptosis of human myeloid leukemia cells

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12 December 2020

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

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12 December 2020

Specific caspase pathways are activated in the two stages of cerebral infarction.

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12 December 2020

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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12 December 2020

Induction of caspase-3-like protease may mediate delayed neuronal death in the hippocampus after transient cerebral ischemia.

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12 December 2020

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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12 December 2020

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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12 December 2020

Essential role of CED-4 oligomerization in CED-3 activation and apoptosis

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12 December 2020

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

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12 December 2020

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

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12 December 2020

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination

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12 December 2020

An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

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12 December 2020

Inhibition of caspases prevents cell death of hippocampal CA1 neurons, but not impairment of hippocampal long-term potentiation following global ischemia

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12 December 2020

The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32

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12 December 2020

FLICE Induced Apoptosis in a Cell-free System

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12 December 2020

Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases

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12 December 2020

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

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12 December 2020

The quantification of cerebral infarction following focal ischemia in the rat: influence of strain, arterial pressure, blood glucose concentration, and age.

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12 December 2020

Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c.

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12 December 2020

Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family

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12 December 2020

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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12 December 2020

Inhibition of human caspases by peptide-based and macromolecular inhibitors

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12 December 2020

Reversible middle cerebral artery occlusion in rats using an intraluminal thread technique

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12 December 2020

Structural basis of procaspase-9 recruitment by the apoptotic protease-activating factor 1

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12 December 2020

The Bcl-2 protein family: arbiters of cell survival

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12 December 2020

Identifiers

DOI

10.1023/A:1019921904378

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11 February 2018

Dimensions Publication ID

1012908819

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11 February 2018