An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9 (Q22009407)

PubMed

7 February 2023

Y Li

1 reference

7 February 2023

X Liu

series ordinal

author given names

author last names

Liu

1 reference

PubMed

7 February 2023

X Wang

series ordinal

author given names

author last names

Wang

1 reference

PubMed

Journal of Biological Chemistry

7 February 2023

language of work or name

English

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publication date

23 April 1999

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published in

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volume

274

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issue

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page(s)

11549-56

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.11549

7 January 2021

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

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DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

1 reference

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

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7 January 2021

Cytochrome c: can't live with it--can't live without it.

1 reference

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7 January 2021

Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

1 reference

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7 January 2021

Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

1 reference

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7 January 2021

FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.11549

7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.11549

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Differential requirement for caspase 9 in apoptotic pathways in vivo.

1 reference

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Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development

1 reference

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7 January 2021

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.11549

7 January 2021

Caenorhabditis elegans CED-4 stimulates CED-3 processing and CED-3-induced

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.17.11549

7 January 2021

Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization

1 reference

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7 January 2021

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1 reference

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The ancient regulatory-protein family of WD-repeat proteins

1 reference

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Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution

1 reference

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Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases

1 reference

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7 January 2021

Proteolysis of fodrin (non-erythroid spectrin) during apoptosis.

1 reference

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7 January 2021

WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation

1 reference

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7 January 2021

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1 reference

7 January 2021

Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

1 reference

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

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Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

1 reference

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Caspase-3-Generated Fragment of Gelsolin: Effector of Morphological Change in Apoptosis

1 reference

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Caspases: enemies within

1 reference

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Essential role of CED-4 oligomerization in CED-3 activation and apoptosis

1 reference

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7 January 2021