Mapping the Energetic Epitope of an Antibody/Interleukin-23 Interaction with Hydrogen/Deuterium Exchange, Fast Photochemical Oxidation of Proteins Mass Spectrometry, and Alanine Shave Mutagenesis. (Q48245517)

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scientific article published on 9 February 2017

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English	Mapping the Energetic Epitope of an Antibody/Interleukin-23 Interaction with Hydrogen/Deuterium Exchange, Fast Photochemical Oxidation of Proteins Mass Spectrometry, and Alanine Shave Mutagenesis.	scientific article published on 9 February 2017

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2 April 2020

Mapping the Energetic Epitope of an Antibody/Interleukin-23 Interaction with Hydrogen/Deuterium Exchange, Fast Photochemical Oxidation of Proteins Mass Spectrometry, and Alanine Shave Mutagenesis (English)

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Richard Y-C Huang

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Michael L. Gross

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Lumelle A Schneeweis

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Jing Li

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Hui Wei

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Stanley R Krystek

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Derek Bond

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Ty M Brender

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Daniel Cohen

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Jena Feiner

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Nels Hamacher

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Johanna Harshman

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Susan H Julien

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Zheng Lin

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Kristina Moore

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Luciano Mueller

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Claire Noriega

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Preeti Sejwal

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Paul Sheppard

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Brenda Stevens

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Guodong Chen

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9 February 2017

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Analytical Chemistry

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2250-2258

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2 April 2020

Applications of hydrogen/deuterium exchange MS from 2012 to 2014.

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22 May 2018

Fast photochemical oxidation of proteins (FPOP) maps the epitope of EGFR binding to adnectin

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The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing

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22 May 2018

Hydrogen/deuterium exchange mass spectrometry for probing higher order structure of protein therapeutics: methodology and applications

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Identification and mapping of linear antibody epitopes in human serum albumin using high-density Peptide arrays.

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Protein analysis by shotgun/bottom-up proteomics

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Ustekinumab induction and maintenance therapy in refractory Crohn's disease

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Structures of adnectin/protein complexes reveal an expanded binding footprint

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Interleukin-23: as a drug target for autoimmune inflammatory diseases

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Fast photochemical oxidation of proteins for epitope mapping

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Hydrogen exchange mass spectrometry for studying protein structure and dynamics

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The IL-23/Th17 axis in the immunopathogenesis of psoriasis

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Crystal structures of the pro-inflammatory cytokine interleukin-23 and its complex with a high-affinity neutralizing antibody

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22 May 2018

Modulation of CLA, IL-12R, CD40L, and IL-2Ralpha expression and inhibition of IL-12- and IL-23-induced cytokine secretion by CNTO 1275

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12 December 2020

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Isotope effects in peptide group hydrogen exchange

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12 December 2020

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IL-23: a master regulator in Crohn disease

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10.1021/ACS.ANALCHEM.6B03058

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