Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer (Q47741752)

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scientific article published in August 2017

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English	Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer	scientific article published in August 2017

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scholarly article

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PubMed publication ID

5 February 2018

http://europepmc.org/abstract/MED/28768804

Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer (English)

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5 February 2018

http://europepmc.org/abstract/MED/28768804

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7 June 2020

Geoffrey J. Lindeman

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7 June 2020

Delphine Mérino

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7 June 2020

James R Whittle

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7 June 2020

François Vaillant

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7 June 2020

Antonin Serrano

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7 June 2020

Guillaume Lessene

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Goknur Giner

6

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7 June 2020

Ana Leticia Maragno

7

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7 June 2020

Maïa Chanrion

8

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7 June 2020

Emilie Schneider

9

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7 June 2020

Grant Dewson

12

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7 June 2020

Julius Gräsel

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7 June 2020

Kevin Liu

14

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7 June 2020

David Segal

16

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7 June 2020

Olivier Geneste

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7 June 2020

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1 August 2017

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5 February 2018

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Science Translational Medicine

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7 June 2020

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7 June 2020

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7 June 2020

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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.

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A survey of the anti-apoptotic Bcl-2 subfamily expression in cancer types provides a platform to predict the efficacy of Bcl-2 antagonists in cancer therapy

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21 January 2018

MCL-1 inhibition provides a new way to suppress breast cancer metastasis and increase sensitivity to dasatinib

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Myeloid cell leukemia-1 inversely correlates with glycogen synthase kinase-3beta activity and associates with poor prognosis in human breast cancer.

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Myeloid cell leukemia-1 is an important apoptotic survival factor in triple-negative breast cancer

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MCL-1 Is a Key Determinant of Breast Cancer Cell Survival: Validation of MCL-1 Dependency Utilizing a Highly Selective Small Molecule Inhibitor

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Herceptin sensitizes ErbB2-overexpressing cells to apoptosis by reducing antiapoptotic Mcl-1 expression

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A competitive stapled peptide screen identifies a selective small molecule that overcomes MCL-1-dependent leukemia cell survival

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Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax).

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21 January 2018

The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer

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21 January 2018

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

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21 January 2018

S63845, an MCL-1 Selective BH3 Mimetic: Another Arrow in Our Quiver.

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Comprehensive molecular portraits of human breast tumours

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10.1126/SCITRANSLMED.AAM7049

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28768804%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28768804%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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