c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1 (Q35218681)

7 August 2017

title

c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1 (English)

1 reference

7 August 2017

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1 reference

Loïc Campion

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Pascal Jézéquel

object named as

Pascal Jézéquel

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Frederique Braun

object named as

Frédérique Braun

1 reference

7 August 2017

Olivier Coqueret

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Mario Campone

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7 August 2017

Bélinda Noël

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7 August 2017

Cécile Couriaud

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7 August 2017

Morgan Grau

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7 August 2017

Yannis Guillemin

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7 August 2017

Fabien Gautier

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7 August 2017

Wilfried Gouraud

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7 August 2017

Catherine Charbonnel

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7 August 2017

Benjamin Barré

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7 August 2017

Sophie Barillé-Nion

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7 August 2017

Philippe Juin

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7 August 2017

publication date

7 September 2011

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7 August 2017

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7 August 2017

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7 August 2017

page(s)

110

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Resistance to HER2 inhibitors: is addition better than substitution? Rationale for the hypothetical concept of drug sedimentation

7 August 2017

cites work

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13 July 2018

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Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E

13 July 2018

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13 July 2018

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Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival

13 July 2018

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13 July 2018

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Inhibition of mammalian target of rapamycin is required for optimal antitumor effect of HER2 inhibitors against HER2-overexpressing cancer cells

13 July 2018

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Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition.

13 July 2018

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13 July 2018

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S6K1 deficiency protects against apoptosis in hepatocytes

13 July 2018

1 reference

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Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members

13 July 2018

1 reference

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Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer

13 July 2018

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HER2-dependent MMP-7 expression is mediated by activated STAT3.

13 July 2018

1 reference

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Targeting the eukaryotic translation initiation factor 4E for cancer therapy

13 July 2018

1 reference

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Diagnosing and exploiting cancer's addiction to blocks in apoptosis

13 July 2018

1 reference

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Canonical nuclear factor kappaB pathway inhibition blocks myeloma cell growth and induces apoptosis in strong synergy with TRAIL.

13 July 2018

1 reference

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Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

13 July 2018

1 reference

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Stattic: a small-molecule inhibitor of STAT3 activation and dimerization

13 July 2018

1 reference

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A common signaling cascade may underlie "addiction" to the Src, BCR-ABL, and EGF receptor oncogenes

13 July 2018

1 reference

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Herceptin sensitizes ErbB2-overexpressing cells to apoptosis by reducing antiapoptotic Mcl-1 expression

13 July 2018

1 reference

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Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants

13 July 2018

1 reference

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Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway.

13 July 2018

1 reference

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HER2-targeting antibodies modulate the cyclin-dependent kinase inhibitor p27Kip1 via multiple signaling pathways

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175201

13 July 2018

Putting the rap on Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175201

Upstream and downstream of mTOR

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175201

A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175201

eIF4E--from translation to transformation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175201

Shooting at survivors: Bcl-2 family members as drug targets for cancer

13 July 2018

1 reference

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FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines

13 July 2018

1 reference

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Biology of HER2 and its importance in breast cancer

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175201

Conversion of a radioresistant phenotype to a more sensitive one by disabling erbB receptor signaling in human cancer cells

13 July 2018

1 reference

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Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions

13 July 2018

1 reference

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Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2.

13 July 2018

1 reference

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Immunohistochemical analysis of Mcl-1 protein in human tissues. Differential regulation of Mcl-1 and Bcl-2 protein production suggests a unique role for Mcl-1 in control of programmed cell death in vivo.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175201

The Skp2 promoter integrates signaling through the NF-kappaB, p53, and Akt/GSK3beta pathways to regulate autophagy and apoptosis.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175201

Immunoselection of breast and ovarian cancer cells with trastuzumab and natural killer cells: selective escape of CD44high/CD24low/HER2low breast cancer stem cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175201

A 38-gene expression signature to predict metastasis risk in node-positive breast cancer after systemic adjuvant chemotherapy: a genomic substudy of PACS01 clinical trial

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175201

Can't kick that oncogene habit

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175201

Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3175201

Overexpression of both p185c-erbB2 and p170mdr-1 renders breast cancer cells highly resistant to taxol

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21899728

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of Bax by BH3 domains during apoptosis: the unfolding of a deadly plot

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21899728

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1476-4598-10-110

1 reference

Dimensions Publication ID

7 August 2017

0 references

1 reference

7 August 2017

1 reference