Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows (Q47700206)

19 February 2018

title

Rapid elicitation of broadly neutralizing antibodies to HIV by immunization in cows (English)

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19 February 2018

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Ian A Wilson

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19 February 2018

Dennis R Burton

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19 February 2018

Andrew B Ward

object named as

Andrew B Ward

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19 February 2018

author name string

Devin Sok

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19 February 2018

Khoa M Le

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19 February 2018

Melissa Vadnais

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19 February 2018

Karen L Saye-Francisco

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19 February 2018

Joseph G Jardine

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19 February 2018

Jonathan L Torres

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19 February 2018

Zachary T Berndsen

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19 February 2018

Leopold Kong

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19 February 2018

Robyn Stanfield

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19 February 2018

Jennifer Ruiz

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19 February 2018

Alejandra Ramos

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19 February 2018

Chi-Hui Liang

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19 February 2018

Patricia L Chen

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19 February 2018

Michael F Criscitiello

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19 February 2018

Waithaka Mwangi

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19 February 2018

Vaughn V Smider

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19 February 2018

language of work or name

English

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publication date

20 July 2017

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19 February 2018

published in

Nature

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19 February 2018

volume

548

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19 February 2018

issue

7665

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19 February 2018

page(s)

108-111

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19 February 2018

Trimeric gp120-specific bovine monoclonal antibodies require cysteine and aromatic residues in CDRH3 for high affinity binding to HIV Env.

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22 May 2018

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Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies

22 May 2018

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Repeated Vaccination of Cows with HIV Env gp140 during Subsequent Pregnancies Elicits and Sustains an Enduring Strong Env-Binding and Neutralising Antibody Response

22 May 2018

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Structural and genetic diversity in antibody repertoires from diverse species

22 May 2018

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HIV-1 VACCINES. HIV-1 neutralizing antibodies induced by native-like envelope trimers

22 May 2018

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Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1

22 May 2018

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Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

22 May 2018

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Comparative analysis of human and mouse immunoglobulin variable heavy regions from IMGT/LIGM-DB with IMGT/HighV-QUEST.

22 May 2018

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Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

22 May 2018

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The functional repertoire of rabbit antibodies and antibody discovery via next-generation sequencing

22 May 2018

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Global panel of HIV-1 Env reference strains for standardized assessments of vaccine-elicited neutralizing antibodies

22 May 2018

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A next-generation cleaved, soluble HIV-1 Env trimer, BG505 SOSIP.664 gp140, expresses multiple epitopes for broadly neutralizing but not non-neutralizing antibodies

22 May 2018

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Reshaping Antibody Diversity

22 May 2018

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Topical gel formulation of broadly neutralizing anti-HIV-1 monoclonal antibody VRC01 confers protection against HIV-1 vaginal challenge in a humanized mouse model

22 May 2018

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Hyperimmune bovine colostrum as a low-cost, large-scale source of antibodies with broad neutralizing activity for HIV-1 envelope with potential use in microbicides.

22 May 2018

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Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization

22 May 2018

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Geneious Basic: an integrated and extendable desktop software platform for the organization and analysis of sequence data

22 May 2018

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Broad neutralization coverage of HIV by multiple highly potent antibodies

22 May 2018

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Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors

22 May 2018

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Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01

22 May 2018

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22 May 2018

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22 May 2018

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Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

22 May 2018

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22 May 2018

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22 May 2018

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Topology representing network enables highly accurate classification of protein images taken by cryo electron-microscope without masking.

22 May 2018

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Bovine IgM antibodies with exceptionally long complementarity-determining region 3 of the heavy chain share unique structural properties conferring restricted VH + Vlambda pairings.

22 May 2018

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Use of a single VH family and long CDR3s in the variable region of cattle Ig heavy chains

22 May 2018

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Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery.

22 May 2018

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Extensive CDR3H length heterogeneity exists in bovine foetal VDJ rearrangements

14 August 2018

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Exceptionally long CDR3H region with multiple cysteine residues in functional bovine IgM antibodies

14 August 2018

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14 August 2018

A vaginal fluid simulant

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Crossref

https://api.crossref.org/works/10.1038%2FNATURE23301

Minimally Mutated HIV-1 Broadly Neutralizing Antibodies to Guide Reductionist Vaccine Design.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1038%2FNATURE23301

A single VH family and long CDR3s are the targets for hypermutation in bovine immunoglobulin heavy chains

21 January 2018

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Crossref

https://api.crossref.org/works/10.1038%2FNATURE23301

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE23301

1 reference

19 February 2018

PMC publication ID

5812458

1 reference

19 February 2018

PubMed publication ID

28726771

1 reference

19 February 2018