Role of Toll-like receptors in infection and immunity: clinical implications (Q47658886)

4 February 2018

review article

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title

Role of Toll-like receptors in infection and immunity: clinical implications (English)

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4 February 2018

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Patricia Cristofaro

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4 February 2018

Steven M Opal

series ordinal

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4 February 2018

publication date

1 January 2006

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4 February 2018

published in

Drugs

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4 February 2018

volume

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4 February 2018

issue

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4 February 2018

page(s)

15-29

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4 February 2018

Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma

cites work

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

Involvement of microbial components and toll-like receptors 2 and 4 in cytokine responses to air pollution particles

21 January 2018

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https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

Escherichia coli LPS-induced LV dysfunction: role of toll-like receptor-4 in the adult heart.

21 January 2018

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Toll-like receptor 4 and NOD2/CARD15 mutations in Hungarian patients with Crohn's disease: phenotype-genotype correlations

21 January 2018

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Gene expression of osteoclast differentiation factor is induced by lipopolysaccharide in mouse osteoblasts via Toll-like receptors

21 January 2018

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https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

A new model for inflammation-induced preterm birth: the role of platelet-activating factor and Toll-like receptor-4

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

Toll-like receptors are temporally involved in host defense

21 January 2018

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https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

TLR signaling in the gut in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

Mechanisms and applications of immune stimulatory CpG oligodeoxynucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

Bacterial DNA and lipopolysaccharide induce synergistic production of TNF-alpha through a post-transcriptional mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

Increased resistance against acute polymicrobial sepsis in mice challenged with immunostimulatory CpG oligodeoxynucleotides is related to an enhanced innate effector cell response

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

TLR ligands can activate dendritic cells to provide a MyD88-dependent negative signal for Th2 cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

Human TLR10 is a functional receptor, expressed by B cells and plasmacytoid dendritic cells, which activates gene transcription through MyD88

21 January 2018

1 reference

https://api.crossref.org/works/10.2165%2F00003495-200666010-00002

Blocking of responses to endotoxin by E5564 in healthy volunteers with experimental endotoxemia

21 January 2018

1 reference

12 December 2020

Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner.

1 reference

12 December 2020

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

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12 December 2020

Synthesis of Toll-like receptor 4 in Kupffer cells and its role in alcohol-induced liver disease

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12 December 2020

Toll-like receptor (TLR) 2 and TLR5, but not TLR4, are required for Helicobacter pylori-induced NF-kappa B activation and chemokine expression by epithelial cells

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12 December 2020

Evolution and integration of innate immune recognition systems: the Toll-like receptors

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12 December 2020

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

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12 December 2020

Toll-like receptors: dysregulation in vivo in patients with acute respiratory distress syndrome.

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12 December 2020

A Toll-like receptor recognizes bacterial DNA

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12 December 2020

The physiological regulation of toll-like receptor expression and function in humans

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12 December 2020

Innate immune recognition

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12 December 2020

Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor‐α‐mediated shock

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12 December 2020

Toll-like receptor 4 antagonist (E5564) prevents the chronic airway response to inhaled lipopolysaccharide

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12 December 2020

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

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12 December 2020

Pseudomonas aeruginosa Flagella Activate Airway Epithelial Cells through asialoGM1 and Toll-Like Receptor 2 as well as Toll-Like Receptor 5

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12 December 2020

A phase I study of the safety and immunogenicity of recombinant hepatitis B surface antigen co-administered with an immunostimulatory phosphorothioate oligonucleotide adjuvant

1 reference

12 December 2020

Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in h

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12 December 2020

Host susceptibility and clinical outcomes in toll-like receptor 5-deficient patients with typhoid fever in Vietnam

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12 December 2020

TLR11 activation of dendritic cells by a protozoan profilin-like protein.

1 reference

12 December 2020

Inhibition of RICK/nuclear factor-kappaB and p38 signaling attenuates the inflammatory response in a murine model of Crohn disease.

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12 December 2020

The polarity of the dorsoventral axis in the Drosophila embryo is defined by an extracellular signal

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12 December 2020

Toll-like receptors, endogenous ligands, and systemic autoimmune disease.

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12 December 2020

Contribution of Toll-like receptor/myeloid differentiation factor 88 signaling to murine liver regeneration

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12 December 2020

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

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12 December 2020

Toll-like receptor (TLR)-3, but not TLR4, agonist protects against genital herpes infection in the absence of inflammation seen with CpG DNA.

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12 December 2020

Phylogenetic perspectives in innate immunity

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12 December 2020

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12 December 2020

Toll-like receptors and immune response in allergic disease

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12 December 2020

Evidence of Toll-like receptor molecules on human platelets

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12 December 2020

Ischemia-reperfusion injury activates innate immunity in rat kidneys

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12 December 2020

Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.

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12 December 2020

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

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12 December 2020

The Toll-like receptors and their role in septic shock

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12 December 2020

Toll-like receptor downstream signaling

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12 December 2020

Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease

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12 December 2020

Three novel mammalian toll-like receptors: gene structure, expression, and evolution

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12 December 2020

The role of innate immunity in acute allograft rejection after lung transplantation.

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12 December 2020

The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products

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12 December 2020

MD-2 binds to bacterial lipopolysaccharide

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12 December 2020

Effect of anti-CD14 monoclonal antibody on clearance of Escherichia coli bacteremia and endotoxemia

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12 December 2020

Therapeutics targeting the innate immune system

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12 December 2020

TH1 immune responses to fully MHC mismatched allografts are diminished in the absence of MyD88, a toll-like receptor signal adaptor protein

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12 December 2020

The role of peptidoglycan in pathogenesis

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12 December 2020

Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis

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12 December 2020

CD36 is a sensor of diacylglycerides

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12 December 2020

Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes

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12 December 2020

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

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12 December 2020

Statins decrease Toll-like receptor 4 expression and downstream signaling in human CD14+ monocytes

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12 December 2020

Bacterial flagellins: mediators of pathogenicity and host immune responses in mucosa

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12 December 2020

LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

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12 December 2020

Involvement of CD14, toll-like receptors 2 and 4, and MyD88 in the host response to the fungal pathogen Cryptococcus neoformans in vivo

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12 December 2020

TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples

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12 December 2020

Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.

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12 December 2020

Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4.

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12 December 2020

Negative regulation of toll-like receptor-mediated immune responses

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12 December 2020

Toll-like receptor signalling

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12 December 2020

Cutting edge: naturally occurring soluble form of mouse Toll-like receptor 4 inhibits lipopolysaccharide signaling

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12 December 2020

Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae

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12 December 2020

Lipopolysaccharide induces expression of genes encoding pro-inflammatory cytokines and the elastin-degrading enzyme, cathepsin S, in human cervical smooth-muscle cells

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12 December 2020

Bench-to-bedside review: Toll-like receptors and their role in septic shock

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12 December 2020

Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

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12 December 2020

The induction of macrophage gene expression by LPS predominantly utilizes Myd88-independent signaling cascades

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12 December 2020

Induction of antitumor immunity by vaccination of dendritic cells transfected with MUC1 RNA

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12 December 2020

A toll-like receptor that prevents infection by uropathogenic bacteria

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12 December 2020

Characterization of Toll-like receptors in the female reproductive tract in humans.

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12 December 2020

Atherosclerosis and innate immune signaling.

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12 December 2020

Immune responses to dsRNA: implications for gene silencing technologies

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12 December 2020

Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling

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12 December 2020

Innate immunity influences long-term outcomes after human lung transplant.

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12 December 2020

The biology of Toll-like receptors

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12 December 2020

Chemokine secretion of rheumatoid arthritis synovial fibroblasts stimulated by Toll-like receptor 2 ligands

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12 December 2020

Toll-like receptor-2 modulates ventricular remodeling after myocardial infarction.

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12 December 2020

Normal keratinocytes express Toll-like receptors (TLRs) 1, 2 and 5: modulation of TLR expression in chronic plaque psoriasis

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12 December 2020

The product of the tobacco mosaic virus resistance gene N: similarity to toll and the interleukin-1 receptor

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12 December 2020

10.2165/00003495-200666010-00002

Identifiers

DOI

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4 February 2018

Dimensions Publication ID

1024984888

0 references

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4 February 2018