PAX8 activates a p53-p21-dependent pro-proliferative effect in high grade serous ovarian carcinoma. (Q47548311)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

PAX8 activates a p53-p21-dependent pro-proliferative effect in high grade serous ovarian carcinoma (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Debora Rosa Bublik

1 reference

13 March 2020

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

author name string

Dima Ghannam-Shahbari

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Eyal Jacob

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Reli Rachel Kakun

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Tanya Wasserman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Lina Korsensky

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Ofir Sternfeld

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Juliana Kagan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Sarit Aviel-Ronen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Edmond Sabo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Sarit Larisch

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

Ruth Perets

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

language of work or name

English

0 references

publication date

30 January 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

page(s)

2213-2224

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

Dysplastic changes in prophylactically removed Fallopian tubes of women predisposed to developing ovarian cancer.

13 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

It's Totally Tubular....Riding The New Wave of Ovarian Cancer Research.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Emerging roles for PAX8 in ovarian cancer and endosalpingeal development

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Getting your Pax straight: Pax proteins in development and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Follicular cells of the thyroid gland require Pax8 gene function

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Congenital hypothyroid female pax8-deficient mice are infertile despite thyroid hormone replacement therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

PAX8 reliably distinguishes ovarian serous tumors from malignant mesothelioma

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

A comprehensive analysis of PAX8 expression in human epithelial tumors

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Expression of pax8 as a useful marker in distinguishing ovarian carcinomas from mammary carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

PAX8 promotes tumor cell growth by transcriptionally regulating E2F1 and stabilizing RB protein

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Loss of PAX8 in high-grade serous ovarian cancer reduces cell survival despite unique modes of action in the fallopian tube and ovarian surface epithelium

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

A candidate precursor to serous carcinoma that originates in the distal fallopian tube.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Integrated genomic analyses of ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Transformation of the fallopian tube secretory epithelium leads to high-grade serous ovarian cancer in Brca;Tp53;Pten models

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Atypical Epithelial Proliferation in Fallopian Tubes in Prophylactic Salpingo-oophorectomy Specimens from BRCA1 and BRCA2 Germline Mutation Carriers

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Fallopian tube intraluminal tumor spread from noninvasive precursor lesions: a novel metastatic route in early pelvic carcinogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Deconstructing p53 transcriptional networks in tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

The consequence of oncomorphic TP53 mutations in ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Mutant p53 expression in fallopian tube epithelium drives cell migration

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Mutant p53 regulates ovarian cancer transformed phenotypes through autocrine matrix deposition.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Loss of p53 function through PAX-mediated transcriptional repression.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Epigenetic inactivation of paired box gene 5, a novel tumor suppressor gene, through direct upregulation of p53 is associated with prognosis in gastric cancer patients.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Pair Box 8 (PAX8) protein expression in high grade, late stage (stages III and IV) ovarian serous carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Value of PAX 8 immunostaining in tumor diagnosis: a review and update

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Evaluating cell lines as tumour models by comparison of genomic profiles

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

YAP induces high-grade serous carcinoma in fallopian tube secretory epithelial cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

p21 Inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

p21 in cancer: intricate networks and multiple activities

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Cytoplasmic p21Cip1 Is Involved in Ras-induced Inhibition of the ROCK/LIMK/Cofilin Pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Wnt signaling in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Eliminating Cancer Stem Cells by Targeting Embryonic Signaling Pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Pax genes: regulators of lineage specification and progenitor cell maintenance

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Male congenital hypothyroid Pax8-/- mice are infertile despite adequate treatment with thyroid hormone.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

PAX2 expression in low malignant potential ovarian tumors and low-grade ovarian serous carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Divergent Roles of PAX2 in the Etiology and Progression of Ovarian Cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Paired Box Gene 5 Is a Novel Tumor Suppressor in Hepatocellular Carcinoma Through Interaction With p53 Signaling Pathway §Δ

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

PAX8-peroxisome proliferator-activated receptor gamma (PPARgamma) disrupts normal PAX8 or PPARgamma transcriptional function and stimulates follicular thyroid cell growth

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Pax8: a marker for carcinoma of Müllerian origin in serous effusions.

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Comprehensive molecular characterization of gastric adenocarcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Cancer chromosomes going to POT1

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

L1-CAM expression in ccRCC correlates with shorter patients survival times and confers chemoresistance in renal cell carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Genome-wide analysis of androgen receptor targets reveals COUP-TF1 as a novel player in human prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states

1 reference

https://api.crossref.org/works/10.1038%2FS41388-017-0040-Z

7 January 2021

Abnormal structure and expression of the p53 gene in human ovarian carcinoma cell lines.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29379162

12 December 2020

inferred from PubMed ID database lookup

The Cancer Genome Atlas Pan-Cancer analysis project

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29379162

12 December 2020

inferred from PubMed ID database lookup

Cytoplasmic p21 is responsible for paclitaxel resistance in ovarian cancer A2780 cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29379162

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41388-017-0040-Z

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29379162%20AND%20SRC:MED&resulttype=core&format=json