Anti-hypoglycemic and hepatocyte-protective effects of hyperoside from Zanthoxylum bungeanum leaves in mice with high-carbohydrate/high-fat diet and alloxan-induced diabetes (Q47370468)

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scientific article published on 25 October 2017

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English	Anti-hypoglycemic and hepatocyte-protective effects of hyperoside from Zanthoxylum bungeanum leaves in mice with high-carbohydrate/high-fat diet and alloxan-induced diabetes	scientific article published on 25 October 2017

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

Anti-hypoglycemic and hepatocyte-protective effects of hyperoside from Zanthoxylum bungeanum leaves in mice with high-carbohydrate/high-fat diet and alloxan-induced diabetes (English)

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

Zanthoxylum bungeanum

object named as

Zanthoxylum bungeanum

1 reference

based on heuristic

inferred from title

author name string

Yali Zhang

1

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

Mimi Wang

2

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

Huanhuan Dong

3

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

Xiaomin Yu

4

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

Jingfang Zhang

5

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

publication date

25 October 2017

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Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

International Journal of Molecular Medicine

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Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

41

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

1

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

77-86

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

Hyperoside pre-treatment prevents glomerular basement membrane damage in diabetic nephropathy by inhibiting podocyte heparanase expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

The Consumption of Synbiotic Bread Containing Lactobacillus sporogenes and Inulin Affects Nitric Oxide and Malondialdehyde in Patients with Type 2 Diabetes Mellitus: Randomized, Double-Blind, Placebo-Controlled Trial.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Antioxidants in liver health

1 reference

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22 May 2018

Type 2 diabetic rats on diet supplemented with chromium malate show improved glycometabolism, glycometabolism-related enzyme levels and lipid metabolism

1 reference

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22 May 2018

The aggravation of mitochondrial dysfunction in nonalcoholic fatty liver disease accompanied with type 2 diabetes mellitus

1 reference

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22 May 2018

Involvement of ATF3 in the negative regulation of iNOS expression and NO production in activated macrophages

1 reference

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22 May 2018

Purification and characterization of flavonoids from the leaves of Zanthoxylum bungeanum and correlation between their structure and antioxidant activity

1 reference

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22 May 2018

Glucosidase inhibitory activity and antioxidant activity of flavonoid compound and triterpenoid compound from Agrimonia Pilosa Ledeb

1 reference

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22 May 2018

Obesity, diabetes mellitus, atherosclerosis and chronic periodontitis: a shared pathology via oxidative stress and mitochondrial dysfunction?

1 reference

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22 May 2018

Hyperoside downregulates the receptor for advanced glycation end products (RAGE) and promotes proliferation in ECV304 cells via the c-Jun N-terminal kinases (JNK) pathway following stimulation by advanced glycation end-products in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Cocoa phenolic extract protects pancreatic beta cells against oxidative stress.

1 reference

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22 May 2018

Diabetic liver injury from streptozotocin is regulated through the caspase-8 homolog cFLIP involving activation of JNK2 and intrahepatic immunocompetent cells

1 reference

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22 May 2018

Role of the Nrf2-ARE pathway in liver diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Quercetin induces insulin secretion by direct activation of L-type calcium channels in pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Oxidative stress associated to dysfunctional adipose tissue: a potential link between obesity, type 2 diabetes mellitus and breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Taurine ameliorate alloxan induced oxidative stress and intrinsic apoptotic pathway in the hepatic tissue of diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Comparison of oxidant/antioxidant, detoxification systems in various tissue homogenates and mitochondria of rats with diabetes induced by streptozocin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Pretreatment with the total flavone glycosides of Flos Abelmoschus manihot and hyperoside prevents glomerular podocyte apoptosis in streptozotocin-induced diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Quercetin potentiates insulin secretion and protects INS-1 pancreatic β-cells against oxidative damage via the ERK1/2 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Protective effect of quercetin on the morphology of pancreatic beta-cells of streptozotocin-treated diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

NF-kappaB in liver diseases: a target for drug therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

The regulation of ATF3 gene expression by mitogen-activated protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Effects of berberine on diabetes induced by alloxan and a high-fat/high-cholesterol diet in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

A splice variant of stress response gene ATF3 counteracts NF-kappaB-dependent anti-apoptosis through inhibiting recruitment of CREB-binding protein/p300 coactivator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

The roles of ATF3 in glucose homeostasis. A transgenic mouse model with liver dysfunction and defects in endocrine pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Effects of in vitro ozone exposure on peroxidative damage, membrane leakage, and taurine content of rat alveolar macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Insulin-induced hyperphagia in alloxan-diabetic rats fed a high-fat diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

22 May 2018

Ursolic acid protects mouse liver against CCl4-induced oxidative stress and inflammation by the MAPK/NF-κB pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Hyperoside inhibits high-glucose-induced vascular inflammation in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Diabetes mellitus triggers oxidative stress in the liver of alloxan-treated rats: a mechanism for diabetic chronic liver disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Pharmacological evaluation of hyperin for antihyperglycemic activity and effect on lipid profile in diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

The effect of hyperoside on the functional recovery of the ischemic/reperfused isolated rat heart: potential involvement of the extracellular signal-regulated kinase 1/2 signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

The prophylactic role of D-saccharic acid-1,4-lactone against hyperglycemia-induced hepatic apoptosis via inhibition of both extrinsic and intrinsic pathways in diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Clinicopathological features of liver injury in patients with type 2 diabetes mellitus and comparative study of histologically proven nonalcoholic fatty liver diseases with or without type 2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Extraction and identification of three major aldose reductase inhibitors from Artemisia montana

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Kolaviron inhibits dimethyl nitrosamine-induced liver injury by suppressing COX-2 and iNOS expression via NF-kappaB and AP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Linking hepatic transcriptional changes to high-fat diet induced physiology for diabetes-prone and obese-resistant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Mechanisms of inhibited liver tissue repair in toxicant challenged type 2 diabetic rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

The role of NF-kappaB signaling in impaired liver tissue repair in thioacetamide-treated type 1 diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Quercetin, a flavonoid antioxidant, prevents and protects streptozotocin-induced oxidative stress and beta-cell damage in rat pancreas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Increased nitric oxide levels as an early sign of premature aging in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Increased atherosclerosis in diabetic dyslipidemic swine: protection by atorvastatin involves decreased VLDL triglycerides but minimal effects on the lipoprotein profile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Involvement of transcriptional repressor ATF3 in acceleration of caspase protease activation during DNA damaging agent-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

14 August 2018

Phytochemical profiles and antioxidant and antimicrobial activities of the leaves of Zanthoxylum bungeanum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5746319

1 December 2018

Clinical and experimental studies of liver injury in diabetes mellitus. II. Experimental studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antithrombotic and profibrinolytic activities of isorhamnetin-3-O-galactoside and hyperoside

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of hyperoside and isoquercitrin from Camellia sasanqua as antioxidant agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic glucokinase activity is the primary defect in alloxan-induced diabetes of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyphenolics composition of the leaves of Zanthoxylum bungeanum Maxim. grown in Hebei, China, and their radical scavenging activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of umbelliferone on membrane-bound ATPases in streptozotocin-induced diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of obesity on the oxidative stress status and the concentration of leptin in type 2 diabetes mellitus patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperin extracted from Manchurian rhododendron leaf induces apoptosis in human endometrial cancer cells through a mitochondrial pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient quantification of the phenolic profiles of Zanthoxylum bungeanum leaves and correlation between chromatographic fingerprint and antioxidant activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNFalpha-induced ATF3 expression is bidirectionally regulated by the JNK and ERK pathways in vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Morphological and histological studies of Chinese traditional drug "hua jiao" (pericarpium zanthoxyli) and its allied drugs]

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic and pancreatic effects of polyenoylphosphatidylcholine in rats with alloxan-induced diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of kaempferol, a flavonoid compound, on membrane-bound ATPases in streptozotocin-induced diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/29115390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3892/IJMM.2017.3211

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 January 2018

http://europepmc.org/abstract/PMC/5746319

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