Converging Mechanisms of p53 Activation Drive Motor Neuron Degeneration in Spinal Muscular Atrophy. (Q47158820)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

title

Converging Mechanisms of p53 Activation Drive Motor Neuron Degeneration in Spinal Muscular Atrophy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

main subject

spinal muscular atrophy

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

Christian M Simon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

Ya Dai

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

Meaghan Van Alstyne

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

Charalampia Koutsioumpa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

John G Pagiazitis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

Joshua I Chalif

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

Xiaojian Wang

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

Joseph E Rabinowitz

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

Christopher E Henderson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

George Z Mentis

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

publication date

1 December 2017

1 reference

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8 April 2020

1 reference

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8 April 2020

volume

1 reference

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8 April 2020

issue

1 reference

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8 April 2020

page(s)

3767-3780

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

8 April 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/5747328

inferred from PubMed Central ID database lookup

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Cell type- and promoter-specific roles of Ser18 phosphorylation in regulating p53 responses

23 May 2018

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p53 has a direct apoptogenic role at the mitochondria

23 May 2018

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23 May 2018

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23 May 2018

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Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

23 May 2018

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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy

23 May 2018

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23 May 2018

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23 May 2018

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23 May 2018

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Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

23 May 2018

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23 May 2018

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Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy

23 May 2018

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p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain

15 August 2018

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15 August 2018

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15 August 2018

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Ultrastructural analysis and TUNEL demonstrate motor neuron apoptosis in Werdnig-Hoffmann disease

15 August 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/29281826

12 December 2020

inferred from PubMed ID database lookup

SMNDelta7, the major product of the centromeric survival motor neuron (SMN2) gene, extends survival in mice with spinal muscular atrophy and associates with full-length SMN

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PubMed

https://pubmed.ncbi.nlm.nih.gov/29281826

12 December 2020

inferred from PubMed ID database lookup

Abolishing Trp53-dependent apoptosis does not benefit spinal muscular atrophy model mice

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PubMed

https://pubmed.ncbi.nlm.nih.gov/29281826

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.CELREP.2017.12.003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json

8 April 2020

PubMed publication ID

29281826

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29281826%20AND%20SRC:MED&resulttype=core&format=json