Challenges facing the biologist doing chemical genetics (Q46774673)

25 December 2017

title

Challenges facing the biologist doing chemical genetics (English)

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25 December 2017

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25 December 2017

author name string

Jon Soderholm

series ordinal

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25 December 2017

Mike Uehara-Bingen

series ordinal

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25 December 2017

Karsten Weis

series ordinal

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25 December 2017

publication date

1 February 2006

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25 December 2017

published in

Nature Chemical Biology

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25 December 2017

volume

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25 December 2017

issue

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25 December 2017

page(s)

55-58

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25 December 2017

Antiviral activity of brefeldin A and verrucarin A.

cites work

2 references

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

21 January 2018

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7 January 2021

Understanding and controlling the cell cycle with natural products

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Antimicrobial properties of fungal macrolide antibiotics

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7 January 2021

Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Small-molecule screening and profiling by using automated microscopy

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Identification of a novel protein regulating microtubule stability through a chemical approach

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

A genome-wide overexpression screen in yeast for small-molecule target identification

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Screening for cell migration inhibitors via automated microscopy reveals a Rho-kinase inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Computer-based de novo design of drug-like molecules

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Small molecule antagonists of proteins

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

DNA display II. Genetic manipulation of combinatorial chemistry libraries for small-molecule evolution

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

DNA-templated organic synthesis and selection of a library of macrocycles

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Tethering: fragment-based drug discovery

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Molecular evolution: dynamic combinatorial libraries, autocatalytic networks and the quest for molecular function

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Amplification of acetylcholine-binding catenanes from dynamic combinatorial libraries.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Docking and scoring in virtual screening for drug discovery: methods and applications

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Structure-based strategies for drug design and discovery

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Surflex: fully automatic flexible molecular docking using a molecular similarity-based search engine

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

ZINC--a free database of commercially available compounds for virtual screening

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

A specific mechanism of nonspecific inhibition

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

High-throughput assays for promiscuous inhibitors.

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Evaluation of fluorescent compound interference in 4 fluorescence polarization assays: 2 kinases, 1 protease, and 1 phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Impact of a red-shifted dye label for high throughput fluorescence polarization assays of G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO0206-55

7 January 2021

Identifiers

DOI

10.1038/NCHEMBIO0206-55

1 reference

25 December 2017

release_g65bqq4mlvcyhoh3ld4x4fkixi

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/g65bqq4mlvcyhoh3ld4x4fkixi

24 November 2022

mapped directly with Wikidata item

1 reference

25 December 2017