Rapid changes in shear stress induce dissociation of a G alpha(q/11)-platelet endothelial cell adhesion molecule-1 complex (Q46068674)

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English	Rapid changes in shear stress induce dissociation of a G alpha(q/11)-platelet endothelial cell adhesion molecule-1 complex	scientific article

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Europe PubMed Central

PubMed publication ID

19332487

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19 December 2017

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http://europepmc.org/abstract/MED/19332487

title

Rapid changes in shear stress induce dissociation of a G alpha(q/11)-platelet endothelial cell adhesion molecule-1 complex (English)

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PubMed publication ID

19332487

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19 December 2017

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http://europepmc.org/abstract/MED/19332487

main subject

endothelium

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cell adhesion

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author

Benoit Melchior

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5

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19332487

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19 December 2017

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http://europepmc.org/abstract/MED/19332487

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Laura A Otte

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1

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19332487

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http://europepmc.org/abstract/MED/19332487

Kelly S Bell

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2

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19332487

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19 December 2017

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Laurent Loufrani

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3

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19332487

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http://europepmc.org/abstract/MED/19332487

Jiunn-Chern Yeh

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4

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19332487

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19 December 2017

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http://europepmc.org/abstract/MED/19332487

Diep N Dao

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6

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19332487

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http://europepmc.org/abstract/MED/19332487

Hazel Y Stevens

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7

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19332487

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http://europepmc.org/abstract/MED/19332487

Charles R White

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8

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PubMed publication ID

19332487

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http://europepmc.org/abstract/MED/19332487

John A Frangos

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9

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PubMed publication ID

19332487

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19 December 2017

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http://europepmc.org/abstract/MED/19332487

language of work or name

English

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publication date

30 March 2009

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19332487

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19 December 2017

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http://europepmc.org/abstract/MED/19332487

number of pages

9

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Journal of Physiology

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19332487

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19 December 2017

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http://europepmc.org/abstract/MED/19332487

volume

587

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PubMed publication ID

19332487

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19 December 2017

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http://europepmc.org/abstract/MED/19332487

issue

Pt 10

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PubMed publication ID

19332487

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19 December 2017

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http://europepmc.org/abstract/MED/19332487

page(s)

2365-2373

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PubMed publication ID

19332487

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19 December 2017

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http://europepmc.org/abstract/MED/19332487

cites work

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PubMed Central

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Shear stress induced stimulation of mammalian cell metabolism

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The shear stress of it all: the cell membrane and mechanochemical transduction

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G protein-coupled receptors sense fluid shear stress in endothelial cells

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G protein betagamma11 complex translocation is induced by Gi, Gq and Gs coupling receptors and is regulated by the alpha subunit type

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A mechanosensory complex that mediates the endothelial cell response to fluid shear stress

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26 August 2018

PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stress

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26 August 2018

Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature.

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26 August 2018

PECAM-1 interacts with nitric oxide synthase in human endothelial cells: implication for flow-induced nitric oxide synthase activation.

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Rapid activation of Ras by fluid flow is mediated by Galpha(q) and Gbetagamma subunits of heterotrimeric G proteins in human endothelial cells.

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Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: is it a mechanoresponsive molecule?

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Temporal gradients in shear, but not spatial gradients, stimulate endothelial cell proliferation

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Agonist-induced internalization of the G protein G11alpha and thyrotropin-releasing hormone receptors proceed on different time scales

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Fluid flow rapidly activates G proteins in human endothelial cells. Involvement of G proteins in mechanochemical signal transduction

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Steady shear and step changes in shear stimulate endothelium via independent mechanisms--superposition of transient and sustained nitric oxide production

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Flow-induced prostacyclin production is mediated by a pertussis toxin-sensitive G protein

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Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse

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Platelet endothelial cell adhesion molecule-1 is a major SH-PTP2 binding protein in vascular endothelial cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19332487

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12 December 2020

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Role of G proteins in shear stress-mediated nitric oxide production by endothelial cells

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/19332487

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12 December 2020

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Tachykinin-1 receptor stimulates proinflammatory gene expression in lung epithelial cells through activation of NF-kappaB via a G(q)-dependent pathway

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Pharmacological properties of YM-254890, a specific G(alpha)q/11 inhibitor, on thrombosis and neointima formation in mice

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Identifiers

DOI

10.1113/JPHYSIOL.2009.172643

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Europe PubMed Central

PubMed publication ID

19332487

retrieved

19 December 2017

reference URL

http://europepmc.org/abstract/MED/19332487

PMC publication ID

2697304

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PubMed publication ID

19332487

1 reference

stated in

Europe PubMed Central

PubMed publication ID

19332487

retrieved

19 December 2017

reference URL

http://europepmc.org/abstract/MED/19332487

ResearchGate publication ID

229470509

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