PECAM-1 is a critical mediator of atherosclerosis (Q36924371)

17 August 2017

PECAM-1 is a critical mediator of atherosclerosis (English)

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17 August 2017

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Hazel Y Stevens

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17 August 2017

Benoît Melchior

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17 August 2017

Kelly S Bell

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17 August 2017

Sujin Yun

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17 August 2017

Jiunn-Chern Yeh

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17 August 2017

John A Frangos

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17 August 2017

18 September 2008

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Disease Models & Mechanisms

17 August 2017

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17 August 2017

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17 August 2017

2-3

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17 August 2017

175-81; discussion 179

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describes a project that uses

17 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2562188/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior

1 reference

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Platelet endothelial cell adhesion molecule-1 and mechanotransduction in vascular endothelial cells

29 September 2017

1 reference

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Cellular adhesion molecules and cardiovascular disease. Part I. Their expression and role in atherogenesis

29 September 2017

1 reference

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PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis

29 September 2017

1 reference

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Biomechanical activation of vascular endothelium as a determinant of its functional phenotype.

29 September 2017

1 reference

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Molecular mechanisms of lipopolysaccharide induced ICAM-1 expression in A549 cells

29 September 2017

1 reference

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Localization of atherosclerosis: role of hemodynamics

29 September 2017

1 reference

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Spatial and temporal regulation of gap junction connexin43 in vascular endothelial cells exposed to controlled disturbed flows in vitro

29 September 2017

1 reference

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Regulation of connexin-43 gap junctional intercellular communication by mitogen-activated protein kinase

29 September 2017

1 reference

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Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear str

29 September 2017

1 reference

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The pathogenesis of atherosclerosis: a perspective for the 1990s

29 September 2017

1 reference

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Carotid bifurcation atherosclerosis. Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress

29 September 2017

1 reference

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Pulsatile flow and atherosclerosis in the human carotid bifurcation. Positive correlation between plaque location and low oscillating shear stress

29 September 2017

1 reference

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Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries.

29 September 2017

1 reference

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Temporal gradient in shear-induced signaling pathway: involvement of MAP kinase, c-fos, and connexin43.

29 September 2017

1 reference

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Temporal gradient in shear but not steady shear stress induces PDGF-A and MCP-1 expression in endothelial cells: role of NO, NF kappa B, and egr-1.

27 June 2018

1 reference

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Regulation of vascular connexin43 gene expression by mechanical loads

27 June 2018

1 reference

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Cloning of the human gene for intercellular adhesion molecule 1 and analysis of its 5'-regulatory region. Induction by cytokines and phorbol ester

27 June 2018

1 reference

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Calculations of pulsatile flow through a branch: implications for the hemodynamics of atherogenesis

27 June 2018

1 reference

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Hemodynamic shear stresses in mouse aortas: implications for atherogenesis

27 June 2018

1 reference

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A mechanosensory complex that mediates the endothelial cell response to fluid shear stress

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562188

Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562188

PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stress

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562188

Platelet endothelial cell adhesion molecule deficiency or blockade significantly reduces leukocyte emigration in a majority of mouse strains

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562188

PECAM-1 interacts with nitric oxide synthase in human endothelial cells: implication for flow-induced nitric oxide synthase activation.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562188

Reduced expression of endothelial connexin37 and connexin40 in hyperlipidemic mice: recovery of connexin37 after 7-day simvastatin treatment

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562188

Paradoxical overexpression and translocation of connexin43 in homocysteine-treated endothelial cells

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562188

Polymorphisms in the platelet-endothelial cell adhesion molecule-1 (PECAM-1) gene, Asn563Ser and Gly670Arg, associated with myocardial infarction in the Japanese.

4 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2562188

Twenty-fold difference in hemodynamic wall shear stress between murine and human aortas

4 September 2018

1 reference

12 December 2020

The Dynamic Response of Vascular Endothelial Cells to Fluid Shear Stress

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12 December 2020

Patterns of atherosclerosis and their surgical significance

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12 December 2020

Topography of human aortic sudanophilic lesions

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12 December 2020

The proteasome pathway is required for cytokine-induced endothelial-leukocyte adhesion molecule expression

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12 December 2020

Fluid flow and osmotic stress induce tyrosine phosphorylation of an endothelial cell 128 kDa surface glycoprotein

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12 December 2020

Selective inhibition of E-selectin, vascular cell adhesion molecule-1, and intercellular adhesion molecule-1 expression by inhibitors of I kappa B-alpha phosphorylation

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12 December 2020

Focal expression of intercellular adhesion molecule-1 in the human carotid bifurcation

1 reference

12 December 2020

Endothelial Gene Regulation by Laminar Shear Stress

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12 December 2020

Oscillatory shear stress stimulates adhesion molecule expression in cultured human endothelium

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12 December 2020

Upregulation of VCAM-1 and ICAM-1 at atherosclerosis-prone sites on the endothelium in the ApoE-deficient mouse

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12 December 2020

The homozygous combination of Leu125Val and Ser563Asn polymorphisms in the PECAM1 (CD31) gene is associated with early severe coronary heart disease

1 reference

12 December 2020

ICAM-1 deficiency reduces atherosclerotic lesions in double-knockout mice (ApoE(-/-)/ICAM-1(-/-)) fed a fat or a chow diet

1 reference

12 December 2020

Fluid shear stress remodels expression and function of junctional proteins in cultured bone cells

1 reference

12 December 2020

Identifiers

DOI

10.1242/DMM.000547

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17 August 2017

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17 August 2017

PubMed publication ID

19048083

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