Drosophila as a screening tool to study human neurodegenerative diseases (Q45734431)

15 December 2017

title

Drosophila as a screening tool to study human neurodegenerative diseases (English)

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15 December 2017

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Jörg B Schulz

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15 December 2017

Sarah Lenz

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15 December 2017

Peter Karsten

series ordinal

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15 December 2017

Aaron Voigt

series ordinal

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15 December 2017

language of work or name

English

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publication date

21 October 2013

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Journal of Neurochemistry

15 December 2017

published in

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15 December 2017

volume

127

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15 December 2017

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15 December 2017

page(s)

453-460

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The genome sequence of Drosophila melanogaster

15 December 2017

cites work

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Enhancer trapping with a red fluorescent protein reporter in Drosophila

21 January 2018

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Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation

21 January 2018

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On the abundance and distribution of transposable elements in the genome of Drosophila melanogaster.

21 January 2018

1 reference

The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes

21 January 2018

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The Drosophila Gene Disruption Project: Progress Using Transposons With Distinctive Site Specificities

21 January 2018

1 reference

Genetic mapping with SNP markers in Drosophila.

21 January 2018

1 reference

Drosophila, the golden bug, emerges as a tool for human genetics

21 January 2018

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Searching for pattern and mutation in the Drosophila genome with a P-lacZ vector

21 January 2018

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Genome-wide screen for modifiers of ataxin-3 neurodegeneration in Drosophila

21 January 2018

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Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila.

21 January 2018

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Identification of EMS-induced mutations in Drosophila melanogaster by whole-genome sequencing.

21 January 2018

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The mitochondrial chaperone protein TRAP1 mitigates α-Synuclein toxicity

21 January 2018

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Identification of novel genes that modify phenotypes induced by Alzheimer's beta-amyloid overexpression in Drosophila

21 January 2018

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Modeling spinal muscular atrophy in Drosophila

21 January 2018

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Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model

21 January 2018

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Conditional mutagenesis in Drosophila

21 January 2018

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Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

21 January 2018

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Insertional mutagenesis of the Drosophila genome with single P elements

21 January 2018

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Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease.

21 January 2018

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A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

21 January 2018

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RNAi screening in Drosophila cells identifies new modifiers of mutant huntingtin aggregation

21 January 2018

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Aconitase causes iron toxicity in Drosophila pink1 mutants

21 January 2018

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Genome-wide screen for modifiers of Parkinson's disease genes in Drosophila

21 January 2018

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Identification of genes that modify ataxin-1-induced neurodegeneration.

21 January 2018

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Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis.

21 January 2018

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Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration

21 January 2018

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Loss- and gain-of-function analysis of the lipid raft proteins Reggie/Flotillin in Drosophila: they are posttranslationally regulated, and misexpression interferes with wing and eye development

21 January 2018

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21 January 2018

P-element mutagenesis

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GAL4-responsive UAS- tau as a tool for studying the anatomy and development of the Drosophila central nervous system

21 January 2018

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Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

21 January 2018

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Reverse genetics by loss-of-function mosaic analysis in Drosophila.

21 January 2018

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Genetic suppression of polyglutamine toxicity in Drosophila

21 January 2018

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Heritable gene silencing in Drosophila using double-stranded RNA.

21 January 2018

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Mutagenesis by imprecise excision of the piggyBac transposon in Drosophila melanogaster.

21 January 2018

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Building an ommatidium one cell at a time

21 January 2018

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A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes.

21 January 2018

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Drosophila modifier screens to identify novel neuropsychiatric drugs including aminergic agents for the possible treatment of Parkinson's disease and depression

21 January 2018

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Polyglutamine genes interact to modulate the severity and progression of neurodegeneration in Drosophila

21 January 2018

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RNA toxicity is a component of ataxin-3 degeneration in Drosophila

21 January 2018

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Muscleblind, BSF and TBPH are mislocalized in the muscle sarcomere of a Drosophila myotonic dystrophy model.

21 January 2018

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Minos as a genetic and genomic tool in Drosophila melanogaster

21 January 2018

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PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila

21 January 2018

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Mutations affecting segment number and polarity in Drosophila

21 January 2018

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Detection in situ of genomic regulatory elements in Drosophila

21 January 2018

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A conditional tissue-specific transgene expression system using inducible GAL4.

21 January 2018

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Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

21 January 2018

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RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1

21 January 2018

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Mapping and identification of essential gene functions on the X chromosome of Drosophila

21 January 2018

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siRNA vs. shRNA: similarities and differences

21 January 2018

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Targeted mutagenesis by homologous recombination in D. melanogaster

21 January 2018

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Comparative genomics of the eukaryotes

21 January 2018

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Transposable elements as tools for genomics and genetics in Drosophila

21 January 2018

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Gene disruptions using P transposable elements: an integral component of the Drosophila genome project

21 January 2018

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The art and design of genetic screens: Drosophila melanogaster

21 January 2018

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The Toll-->NFkappaB signaling pathway mediates the neuropathological effects of the human Alzheimer's Abeta42 polypeptide in Drosophila

21 January 2018

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A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac

21 January 2018

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Genome-wide manipulations of Drosophila melanogaster with transposons, Flp recombinase, and ΦC31 integrase.

21 January 2018

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Large-scale screen for modifiers of ataxin-3-derived polyglutamine-induced toxicity in Drosophila

21 January 2018

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Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

21 January 2018

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A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/JNC.12446

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15 December 2017

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