The competing roles of virus replication and hepatocyte death rates in the emergence of drug-resistant mutants: theoretical considerations. (Q45420047)

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16 January 2020

title

The competing roles of virus replication and hepatocyte death rates in the emergence of drug-resistant mutants: theoretical considerations (English)

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16 January 2020

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16 January 2020

Samuel Litwin

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16 January 2020

Eugene Toll

series ordinal

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16 January 2020

William S Mason

series ordinal

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16 January 2020

language of work or name

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1 December 2005

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Journal of Clinical Virology

16 January 2020

published in

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16 January 2020

volume

34 Suppl 1

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16 January 2020

page(s)

S96-S107

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Half-life of the duck hepatitis B virus covalently closed circular DNA pool in vivo following inhibition of viral replication

16 January 2020

cites work

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Identification and characterization of mutations in hepatitis B virus resistant to lamivudine. Lamivudine Clinical Investigation Group

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Hepatitis-B-virus resistance to lamivudine given for recurrent infection after orthotopic liver transplantation

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Long-term entecavir treatment results in sustained antiviral efficacy and prolonged life span in the woodchuck model of chronic hepatitis infection.

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Increased hepatocyte turnover and inhibition of woodchuck hepatitis B virus replication by adefovir in vitro do not lead to reduction of the closed circular DNA.

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Entecavir therapy combined with DNA vaccination for persistent duck hepatitis B virus infection

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Evidence that hepatocyte turnover is required for rapid clearance of duck hepatitis B virus during antiviral therapy of chronically infected ducks

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7 January 2021

Role of additional mutations outside the YMDD motif of hepatitis B virus polymerase in L(-)SddC (3TC) resistance

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Sensitivity of L-(-)2,3-dideoxythiacytidine resistant hepatitis B virus to other antiviral nucleoside analogues

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Kinetic analysis of wild-type and YMDD mutant hepatitis B virus polymerases and effects of deoxyribonucleotide concentrations on polymerase activity

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Mutation rate of the hepadnavirus genome

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Detection of hepatitis b virus dna sequences in infected hepatocytes by in situ cytohybridisation

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Lamivudine resistance inimmunocompetent chronic hepatitis B

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Kinetics of duck hepatitis B virus infection following low dose virus inoculation: one virus DNA genome is infectious in neonatal ducks

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Prevalence and clinical correlates of YMDD variants during lamivudine therapy for patients with chronic hepatitis B.

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Extended lamivudine treatment in patients with chronic hepatitis B enhances hepatitis B e antigen seroconversion rates: results after 3 years of therapy

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7 January 2021

Analysis of hepatitis B viral load decline under potent therapy: complex decay profiles observed.

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Selection of mutations in the hepatitis B virus polymerase during therapy of transplant recipients with lamivudine

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A duck hepatitis B virus strain with a knockout mutation in the putative X ORF shows similar infectivity and in vivo growth characteristics to wild-type virus.

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Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective

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YMDD motif in hepatitis B virus DNA polymerase influences on replication and lamivudine resistance: A study by in vitro full-length viral DNA transfection

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7 January 2021

Antiviral activity of clevudine [L-FMAU, (1-(2-fluoro-5-methyl-beta, L-arabinofuranosyl) uracil)] against woodchuck hepatitis virus replication and gene expression in chronically infected woodchucks (Marmota monax).

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7 January 2021

Frequency of spontaneous mutations in an avian hepadnavirus infection

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7 January 2021

Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region

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7 January 2021

Mutations in hepatitis B DNA polymerase associated with resistance to lamivudine do not confer resistance to adefovir in vitro

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

10.1016/S1386-6532(05)80018-6

Identifiers

DOI

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16 January 2020

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