Kinetic analysis of wild-type and YMDD mutant hepatitis B virus polymerases and effects of deoxyribonucleotide concentrations on polymerase activity (Q39651471)

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scientific article published on April 2002

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English	Kinetic analysis of wild-type and YMDD mutant hepatitis B virus polymerases and effects of deoxyribonucleotide concentrations on polymerase activity	scientific article published on April 2002

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scholarly article

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Europe PubMed Central

PMC publication ID

13 September 2017

Kinetic analysis of wild-type and YMDD mutant hepatitis B virus polymerases and effects of deoxyribonucleotide concentrations on polymerase activity (English)

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Hepatitis B virus

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

J Patrick Condreay

8

object named as

Patrick Condreay

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Europe PubMed Central

PMC publication ID

13 September 2017

author name string

Richard K Gaillard

1

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Europe PubMed Central

PMC publication ID

13 September 2017

Jennifer Barnard

2

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Europe PubMed Central

PMC publication ID

13 September 2017

Vincent Lopez

3

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Europe PubMed Central

PMC publication ID

13 September 2017

Paula Hodges

4

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Eric Bourne

5

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Lance Johnson

6

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

Marchelle I Allen

7

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Europe PubMed Central

PMC publication ID

13 September 2017

Wayne H Miller

9

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Europe PubMed Central

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13 September 2017

Lynn D Condreay

10

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Europe PubMed Central

PMC publication ID

13 September 2017

language of work or name

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publication date

1 April 2002

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Europe PubMed Central

PMC publication ID

13 September 2017

Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

PMC publication ID

13 September 2017

46

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Europe PubMed Central

PMC publication ID

13 September 2017

4

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Europe PubMed Central

PMC publication ID

13 September 2017

1005-1013

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Europe PubMed Central

PMC publication ID

13 September 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC127103/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Nomenclature for antiviral-resistant human hepatitis B virus mutations in the polymerase region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

14 September 2017

The polymerase L528M mutation cooperates with nucleotide binding-site mutations, increasing hepatitis B virus replication and drug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

14 September 2017

Hepatitis B virus biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

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Intracellular compartmentation of organelles and gradients of low molecular weight species

1 reference

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14 September 2017

Susceptibility of lamivudine-resistant hepatitis B virus to other reverse transcriptase inhibitors

1 reference

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14 September 2017

Sensitivity of L-(-)2,3-dideoxythiacytidine resistant hepatitis B virus to other antiviral nucleoside analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

14 September 2017

YMDD motif in hepatitis B virus DNA polymerase influences on replication and lamivudine resistance: A study by in vitro full-length viral DNA transfection

1 reference

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14 September 2017

The hepatitis B virus M539V polymerase variation responsible for 3TC resistance also confers cross-resistance to other nucleoside analogues.

1 reference

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Transient and stable gene expression in mammalian cells transduced with a recombinant baculovirus vector

1 reference

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In vitro inhibition of hepadnavirus polymerases by the triphosphates of BMS-200475 and lobucavir.

1 reference

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14 September 2017

The M539V polymerase variant of human hepatitis B virus demonstrates resistance to 2'-deoxy-3'-thiacytidine and a reduced ability to synthesize viral DNA

1 reference

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DNA polymerase activity of hepatitis B virus particles: differential inhibition by L-enantiomers of nucleotide analogs

1 reference

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Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.

1 reference

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14 September 2017

High-capacity in vitro assessment of anti-hepatitis B virus compound selectivity by a virion-specific polymerase chain reaction assay

1 reference

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14 September 2017

Physiological concentrations of purines and pyrimidines

1 reference

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14 September 2017

Mutations in the epsilon sequences of human hepatitis B virus affect both RNA encapsidation and reverse transcription

1 reference

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14 September 2017

Interactions between deoxyribonucleotide and DNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

14 September 2017

Production of hepatitis B virus particles in Hep G2 cells transfected with cloned hepatitis B virus DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

14 September 2017

Identification of four conserved motifs among the RNA-dependent polymerase encoding elements

1 reference

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14 September 2017

1 reference

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Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli

1 reference

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Limiting deoxynucleoside triphosphate concentrations emphasize the processivity defect of lamivudine-resistant variants of human immunodeficiency virus type 1 reverse transcriptase

1 reference

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Intracellular metabolism of (-)- and (+)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine in HepG2 derivative 2.2.15 (subclone P5A) cells

1 reference

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Tbe complete nudeotide sequences of the cloned hepatitis B vims DNA; subtype adr and adw

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

14 September 2017

Ribonucleotide reductase and deoxyribonucleotide pools.

1 reference

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14 September 2017

Hepatitis B virus mutants associated with 3TC and famciclovir administration are replication defective

1 reference

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Cell cycle-dependent metabolism of pyrimidine deoxynucleoside triphosphates in CEM cells

1 reference

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The intracellular activation of lamivudine (3TC) and determination of 2'-deoxycytidine-5'-triphosphate (dCTP) pools in the presence and absence of various drugs in HepG2 cells

1 reference

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17 June 2018

In vivo dynamics and pathogenicity of wild-type and resistant Hepatitis B virus during long-term lamivudine monotherapy - a clinical note

1 reference

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17 June 2018

Functional analysis of mutations conferring lamivudine resistance on hepatitis B virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

17 June 2018

Identification and characterization of mutations in hepatitis B virus resistant to lamivudine. Lamivudine Clinical Investigation Group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

17 June 2018

Deoxyribonucleoside triphosphate pools in regenerating rat liver: effect of hydroxyurea and exogenous deoxypyrimidines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

17 June 2018

Nucleotide sequence of the gene coding for the major protein of hepatitis B virus surface antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

17 June 2018

Clearance of the original hepatitis B virus YMDD-motif mutants with emergence of distinct lamivudine-resistant mutants during prolonged lamivudine therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

21 August 2018

Emergence of YMDD motif mutants of hepatitis B virus during lamivudine treatment of immunocompetent type B hepatitis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

21 August 2018

Novel patterns of amino acid mutations in the hepatitis B virus polymerase in association with resistance to lamivudine therapy in japanese patients with chronic hepatitis B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

21 August 2018

Acute exacerbation and hepatitis B virus clearance after emergence of YMDD motif mutation during lamivudine therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

21 August 2018

Mutations in hepatitis B DNA polymerase associated with resistance to lamivudine do not confer resistance to adefovir in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

21 August 2018

Role of additional mutations outside the YMDD motif of hepatitis B virus polymerase in L(-)SddC (3TC) resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

21 August 2018

Emergence and takeover of YMDD motif mutant hepatitis B virus during long-term lamivudine therapy and re-takeover by wild type after cessation of therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

21 August 2018

Identification of more than one mutation in the hepatitis B virus polymerase gene arising during prolonged lamivudine treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

21 August 2018

Transient emergence of hepatitis B variants in a patient with chronic hepatitis B resistant to lamivudine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

21 August 2018

Use of baculovirus expression vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

21 August 2018

Development of a human immunodeficiency virus-1 in vitro DNA synthesis system to study reverse transcriptase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=127103

21 August 2018

Deoxyribonucleotide pools during liver regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/11897582

12 December 2020

based on heuristic

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Purine and pyrimidine nucleotide patterns of normal, differentiating, and regenerating liver and of hepatomas in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11897582

12 December 2020

based on heuristic

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Determination of pyrimidine ribotide and deoxyribotide pools in cultured cells and mouse liver by high-performance liquid chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/11897582

12 December 2020

based on heuristic

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Determination of ribonucleoside triphosphates and deoxyribonucleoside triphosphates in Novikoff hepatoma cells by high-performance liquid chromatography

1 reference

https://pubmed.ncbi.nlm.nih.gov/11897582

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzymatic assay for deoxyribonucleoside triphosphates using synthetic oligonucleotides as template primers

1 reference

https://pubmed.ncbi.nlm.nih.gov/11897582

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lamivudine resistance inimmunocompetent chronic hepatitis B

1 reference

https://pubmed.ncbi.nlm.nih.gov/11897582

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of deoxynucleotide pools by substrate cycles

1 reference

https://pubmed.ncbi.nlm.nih.gov/11897582

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of hepatitis B viremia and emergence of YMDD variants in patients with chronic hepatitis B treated with lamivudine

1 reference

https://pubmed.ncbi.nlm.nih.gov/11897582

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.46.4.1005-1013.2002

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 September 2017

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