Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila. (Q44854880)

From Wikidata

Jump to navigation Jump to search

scientific article published in April 2004

edit

Language	Label	Description	Also known as
English	Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila.	scientific article published in April 2004

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

title

Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila (English)

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

main subject

Drosophila

0 references

neurodegeneration

1 reference

based on heuristic

inferred from title

author

Doris Kretzschmar

series ordinal

2

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

author name string

Isabell Greeve

series ordinal

1

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

Jakob-Andreas Tschäpe

series ordinal

3

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

Anika Beyn

series ordinal

4

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

Claire Brellinger

series ordinal

5

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

Michaela Schweizer

series ordinal

6

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

Roger M Nitsch

series ordinal

7

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

Rita Reifegerste

series ordinal

8

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

language of work or name

English

0 references

publication date

1 April 2004

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

published in

Journal of Neuroscience

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

volume

24

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

issue

16

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

page(s)

3899-3906

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

cites work

Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translating cell biology into therapeutic advances in Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic activities of wild-type and Alzheimer's disease-related mutant presenilins in Drosophila melanogaster

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and cloning of amyloid precursor protein beta-secretase from human brain

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling human neurodegenerative diseases in Drosophila: on a wing and a prayer.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genome sequence of Drosophila melanogaster

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proteolytic processing and cell biological functions of the amyloid precursor protein

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studying human neurodegenerative diseases in flies and worms

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of post-translational modification in beta-amyloid precursor protein processing

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cell biology of Alzheimer's disease: uncovering the secrets of secretases

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aph-1, Pen-2, and Nicastrin with Presenilin generate an active gamma-Secretase complex

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-amyloid precursor protein of Alzheimer disease occurs as 110- to 135-kilodalton membrane-associated proteins in neural and nonneural tissues.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transposition of cloned P elements into Drosophila germ line chromosomes.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic Transformation of Drosophila with Transposable Element Vectors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of heterogeneous A4 peptides in human cerebrospinal fluid and blood by a newly developed sensitive Western blot assay

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Skeletal and CNS defects in Presenilin-1-deficient mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of Alzheimer's amyloid precursor protein (APP) by secretases occurs after O-glycosylation of APP in the protein secretory pathway. Identification of intracellular compartments in which APP cleavage occurs without using toxic agents that int

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for the beta-amyloid precursor protein in memory?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15102905

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1523/JNEUROSCI.0283-04.2004

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

PMC publication ID

6729409

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

PubMed publication ID

15102905

1 reference

stated in

Europe PubMed Central

PMC publication ID

6729409

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15102905%20AND%20SRC:MED&resulttype=core&format=json

retrieved

27 December 2019

 

Sitelinks

Wikipedia(0 entries)

edit

Wikibooks(0 entries)

edit

Wikinews(0 entries)

edit

Wikiquote(0 entries)

edit

Wikisource(0 entries)

edit

Wikiversity(0 entries)

edit

Wikivoyage(0 entries)

edit

Wiktionary(0 entries)

edit

Multilingual sites(0 entries)

edit

Retrieved from "https://www.wikidata.org/w/index.php?title=Q44854880&oldid=2165530257"