Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes (Q44472346)

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English	Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 December 2017

Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes (English)

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3 December 2017

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Kristi A. Kohlmeier

10

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3 December 2017

James A. Richardson

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James A Richardson

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3 December 2017

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Jon T Willie

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Richard M Chemelli

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Christopher M Sinton

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Shigeru Tokita

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S Clay Williams

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Yaz Y Kisanuki

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Jacob N Marcus

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Charlotte Lee

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Joel K Elmquist

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Christopher S Leonard

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Robert E Hammer

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Masashi Yanagisawa

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3 December 2017

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publication date

1 June 2003

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3 December 2017

38

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5

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715-730

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3 December 2017

Diagnostic aspects of narcolepsy

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EEG spectral analysis of the sleep-onset period in narcoleptics and normal sleepers

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Canine model of narcolepsy: genetic and developmental determinants.

1 reference

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7 January 2021

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Orexins (hypocretins) directly excite tuberomammillary neurons

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7 January 2021

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Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

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The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

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7 January 2021

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The nature of the narcoleptic sleep attack

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Narcolepsy: unequivocal diagnosis after split-screen, video-polysomnographic analysis of a prolonged cataplectic attack.

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Diagnosing narcolepsy through the simultaneous clinical and electrophysiologic analysis of cataplexy.

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7 January 2021

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Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus.

1 reference

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7 January 2021

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A study on cataplexy

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Altered states of consciousness in disorders of daytime sleepiness

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Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity

1 reference

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Arousal effect of orexin A depends on activation of the histaminergic system

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Hypocretin/orexin, sleep and narcolepsy

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Identification and functional analysis of mutations in the hypocretin (orexin) genes of narcoleptic canines

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The effect of orexin-A and -B on the histamine release in the anterior hypothalamus in rats

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CSF hypocretin-1 (orexin-A) concentrations in narcolepsy with and without cataplexy and idiopathic hypersomnia

1 reference

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The hypocretin/orexin ligand-receptor system: implications for sleep and sleep disorders.

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Instrumental and pharmacological paradoxical sleep deprivation in mice: strain differences

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Release of hypocretin (orexin) during waking and sleep states.

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7 January 2021

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Electroencephalographic correlates of cataplectic attacks in narcoleptic canines

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7 January 2021

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Histaminergic descending inputs to the mesopontine tegmentum and their role in the control of cortical activation and wakefulness in the cat.

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The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

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Sleep cycle organization in narcoleptic and normal dogs

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Differential expression of orexin receptors 1 and 2 in the rat brain

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Brain structures and mechanisms involved in the generation of NREM sleep: focus on the preoptic hypothalamus

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The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias

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Sleeping with the hypothalamus: emerging therapeutic targets for sleep disorders

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Sleep studies on canine narcolepsy: pattern and cycle comparisons between affected and normal dogs

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Decreased brain histamine content in hypocretin/orexin receptor-2 mutated narcoleptic dogs

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A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

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1 reference

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Innervation of histaminergic tuberomammillary neurons by GABAergic and galaninergic neurons in the ventrolateral preoptic nucleus of the rat.

1 reference

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7 January 2021

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Evidence implicating a role for orexin-1 receptor modulation of paradoxical sleep in the rat

1 reference

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1 reference

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based on heuristic

inferred from DOI database lookup

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Reduced number of hypocretin neurons in human narcolepsy

1 reference

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7 January 2021

based on heuristic

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1 reference

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1 reference

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inferred from DOI database lookup

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10.1016/S0896-6273(03)00330-1

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Europe PubMed Central

PubMed publication ID

3 December 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 December 2017

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