Pristimerin induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation by blocking NF-kappaB signaling and depleting Bcr-Abl (Q33944952)

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English	Pristimerin induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation by blocking NF-kappaB signaling and depleting Bcr-Abl	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

30 July 2017

Pristimerin induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation by blocking NF-kappaB signaling and depleting Bcr-Abl (English)

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Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Zhongzheng Lu

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Yanli Jin

2

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Europe PubMed Central

PubMed publication ID

30 July 2017

Chun Chen

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Juan Li

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Qi Cao

5

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Jingxuan Pan

6

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Europe PubMed Central

PubMed publication ID

30 July 2017

publication date

19 May 2010

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Europe PubMed Central

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30 July 2017

Molecular Cancer

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Europe PubMed Central

PubMed publication ID

30 July 2017

9

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Europe PubMed Central

PubMed publication ID

30 July 2017

112

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

The antitumor activity of homoharringtonine against human mast cells harboring the KIT D816V mutation

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RNA polymerase - an important molecular target of triptolide in cancer cells

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Celastrol, a novel HSP90 inhibitor, depletes Bcr-Abl and induces apoptosis in imatinib-resistant chronic myelogenous leukemia cells harboring T315I mutation

1 reference

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Identification of a potent natural triterpenoid inhibitor of proteosome chymotrypsin-like activity and NF-kappaB with antimyeloma activity in vitro and in vivo

1 reference

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Modification of cysteine residue in p65 subunit of nuclear factor-kappaB (NF-kappaB) by picroliv suppresses NF-kappaB-regulated gene products and potentiates apoptosis.

1 reference

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EXEL-0862, a novel tyrosine kinase inhibitor, induces apoptosis in vitro and ex vivo in human mast cells expressing the KIT D816V mutation

1 reference

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1 reference

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The triterpenoid quinonemethide pristimerin inhibits induction of inducible nitric oxide synthase in murine macrophages

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2893099

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1 reference

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1 reference

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[Estimation of level of soluble form PECAM-1, ICAM-2 and TNF-alpha, IL-18 in serum patients with chronic myelogenic leukemia]

1 reference

https://pubmed.ncbi.nlm.nih.gov/20482842

12 December 2020

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10.1186/1476-4598-9-112

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Europe PubMed Central

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30 July 2017

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https://scigraph.springernature.com/pub.10.1186/1476-4598-9-112

9 September 2019

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Europe PubMed Central

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30 July 2017

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Europe PubMed Central

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30 July 2017

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