Variations in Mre11/Rad50/Nbs1 status and DNA damage-induced S-phase arrest in the cell lines of the NCI60 panel (Q33914285)

30 July 2017

title

Variations in Mre11/Rad50/Nbs1 status and DNA damage-induced S-phase arrest in the cell lines of the NCI60 panel (English)

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30 July 2017

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Kristen M Garner

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30 July 2017

Alan Eastman

series ordinal

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30 July 2017

language of work or name

English

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publication date

27 May 2011

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30 July 2017

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30 July 2017

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30 July 2017

page(s)

206:1-13

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Principles of cancer therapy: oncogene and non-oncogene addiction

30 July 2017

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DNA damage-induced S phase arrest in human breast cancer depends on Chk1, but G2 arrest can occur independently of Chk1, Chk2 or MAPKAPK2.

5 July 2018

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A mutant allele of MRE11 found in mismatch repair-deficient tumor cells suppresses the cellular response to DNA replication fork stress in a dominant negative manner

5 July 2018

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Rapid activation of ATR by ionizing radiation requires ATM and Mre11

5 July 2018

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ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

5 July 2018

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5 July 2018

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Human MRE11 is inactivated in mismatch repair-deficient cancers

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Mutant Nbs1 enhances cisplatin-induced DNA damage and cytotoxicity in head and neck cancer.

5 July 2018

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Crossref

https://api.crossref.org/works/10.1186%2F1471-2407-11-206

COMPARE: a web accessible tool for investigating mechanisms of cell growth inhibition.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1186%2F1471-2407-11-206

Defective p53 signaling in p53 wild-type tumors attenuates p21waf1 induction and cyclin B repression rendering them sensitive to Chk1 inhibitors that abrogate DNA damage-induced S and G2 arrest

21 January 2018

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21 January 2018

Identifiers

DOI

10.1186/1471-2407-11-206

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Dimensions Publication ID

30 July 2017

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30 July 2017

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