Development of a safe live Leishmania vaccine line by gene replacement. (Q33830649)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7479765%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

title

Development of a safe live Leishmania vaccine line by gene replacement (English)

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19 October 2019

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19 October 2019

Frederico Gueiros Filho

series ordinal

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19 October 2019

R G Titus

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19 October 2019

L A de Freitas

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19 October 2019

language of work or name

English

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publication date

1 October 1995

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Proceedings of the National Academy of Sciences of the United States of America

19 October 2019

published in

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19 October 2019

volume

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19 October 2019

issue

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19 October 2019

page(s)

10267-10271

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Plasticity in chromosome number and testing of essential genes in Leishmania by targeting

19 October 2019

cites work

1 reference

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Effective immunization against cutaneous leishmaniasis with recombinant bacille Calmette-Guérin expressing the Leishmania surface proteinase gp63

4 July 2018

1 reference

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Reversion to virulence in Leishmania major correlates with expression of surface lipophosphoglycan

4 July 2018

1 reference

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Selection for bacterial genes that are specifically induced in host tissues: the hunt for virulence factors.

4 July 2018

1 reference

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Transfected Leishmania expressing biologically active IFN-gamma

4 July 2018

1 reference

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Persistence of virulent Leishmania major in murine cutaneous leishmaniasis: a possible hazard for the host

4 July 2018

1 reference

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PTR1: a reductase mediating salvage of oxidized pteridines and methotrexate resistance in the protozoan parasite Leishmania major.

4 July 2018

1 reference

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An avirulent lipophosphoglycan-deficient Leishmania major clone induces CD4+ T cells which protect susceptible BALB/c mice against infection with virulent L. major

4 July 2018

1 reference

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Advantages of measuring changes in the number of viable parasites in murine models of experimental cutaneous leishmaniasis.

4 July 2018

1 reference

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Identification of an infective stage of Leishmania promastigotes.

4 July 2018

1 reference

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A limiting dilution assay for quantifying Leishmania major in tissues of infected mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Immunological regulation and control of experimental leishmaniasis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Salivary gland lysates from the sand fly Lutzomyia longipalpis enhance Leishmania infectivity.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Immunization of susceptible BALB/c mice against Leishmania braziliensis. I. Resistance induced using as immunogen adherent or nonadherent cells from infected mice.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Experiences with vaccines against cutaneous leishmaniasis: of men and mice

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Stable transfection of the human parasite Leishmania major delineates a 30-kilobase region sufficient for extrachromosomal replication and expression

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Oral Salmonella typhimurium (AroA-) vaccine expressing a major leishmanial surface protein (gp63) preferentially induces T helper 1 cells and protective immunity against leishmaniasis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Leishmania infecting man and wild animals in Saudi Arabia. 8. The influence of prior infection with Leishmania arabica on challenge with L. major in man.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Development of a stable Leishmania expression vector and application to the study of parasite surface antigen genes

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Experimental leishmaniasis in humans: review

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Exacerbation of experimental murine cutaneous leishmaniasis with CD4+Leishmania major-specific T cell lines or clones which secrete interferon-γ and mediate parasite-specific delayed-type hypersensitivity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Double targeted gene replacement for creating null mutants

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Establishment of stable, cell-mediated immunity that makes "susceptible" mice resistant to Leishmania major.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Extrachromosomal genetic complementation of surface metalloproteinase (gp63)-deficient Leishmania increases their binding to macrophages

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Is leishmaniasis ever cured?

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Role of T cell subsets during the recall of immunologic memory to Leishmania major

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Selection of bacterial virulence genes that are specifically induced in host tissues

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

On the introduction of genetically modified Leishmania outside the laboratory.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=40777

Vaccination against cutaneous leishmaniasis in mice using nonpathogenic cloned promastigotes of Leishmania major and importance of route of injection

29 October 2018

1 reference

12 December 2020

The reversal of methotrexate toxicity by thymidine with maintenance of antitumour effects

1 reference

12 December 2020

Vaccine development against cutaneous leishmaniasis. Subcutaneous administration of radioattenuated parasites protects CBA mice against virulent Leishmania major challenge

1 reference

12 December 2020

Cutaneous leishmaniasis: The prospects for a killed vaccine

1 reference

12 December 2020

Variants with reduced virulence derived from Leishmania major after mutagen treatment

1 reference

12 December 2020

Vaccination against cutaneous leishmaniasis in a murine model. I. Induction of protective immunity with a soluble extract of promastigotes

1 reference

12 December 2020

Heterologous protection in murine cutaneous leishmaniasis

1 reference

12 December 2020

Gene replacement in parasitic protozoa

1 reference

12 December 2020

Intracellular destruction of Leishmania tropica by macrophages activated with macrophage activating factor/interferon

1 reference

12 December 2020

Isolation and characterization of infective and non-infective clones of Leishmania tropica

1 reference

12 December 2020

Examination of variables in the vaccination of mice against cutaneous leishmaniasis using living avirulent cloned lines and killed promastigotes of Leishmania major

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.92.22.10267

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7479765%20AND%20SRC:MED&resulttype=core&format=json

19 October 2019

0 references

1 reference

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19 October 2019

PubMed publication ID

7479765

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7479765%20AND%20SRC:MED&resulttype=core&format=json