Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice (Q33781761)

29 July 2017

title

Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice (English)

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29 July 2017

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Michelle L Olsen

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29 July 2017

Xiaoping Tong

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29 July 2017

Yan Ao

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29 July 2017

Guido C Faas

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29 July 2017

Sinifunanya E Nwaobi

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29 July 2017

Ji Xu

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29 July 2017

Martin D Haustein

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29 July 2017

Mark A Anderson

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29 July 2017

Istvan Mody

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29 July 2017

Michael V Sofroniew

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29 July 2017

Baljit S Khakh

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29 July 2017

language of work or name

English

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publication date

30 March 2014

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29 July 2017

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

694-703

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describes a project that uses

29 July 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4064471/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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28 July 2018

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Characterization of neurophysiological and behavioral changes, MRI brain volumetry and 1H MRS in zQ175 knock-in mouse model of Huntington's disease.

28 July 2018

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Comprehensive behavioral and molecular characterization of a new knock-in mouse model of Huntington's disease: zQ175.

28 July 2018

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Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors

28 July 2018

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Corticostriatal dysfunction and glutamate transporter 1 (GLT1) in Huntington's disease: interactions between neurons and astrocytes

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In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

28 July 2018

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Mutant huntingtin in glial cells exacerbates neurological symptoms of Huntington disease mice

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STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury

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Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin

28 July 2018

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Up-regulation of GLT1 expression increases glutamate uptake and attenuates the Huntington's disease phenotype in the R6/2 mouse

28 July 2018

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Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration

28 July 2018

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28 July 2018

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Mechanisms of Disease: astrocytes in neurodegenerative disease

28 July 2018

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28 July 2018

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Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

28 July 2018

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Neuronal vulnerability in mouse models of Huntington's disease: membrane channel protein changes

28 July 2018

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28 July 2018

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28 July 2018

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Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1

28 July 2018

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Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice

28 July 2018

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28 July 2018

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

28 July 2018

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28 July 2018

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28 July 2018

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Implication of Kir4.1 channel in excess potassium clearance: an in vivo study on anesthetized glial-conditional Kir4.1 knock-out mice

28 July 2018

1 reference

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Selective induction of astrocytic gliosis generates deficits in neuronal inhibition

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064471

Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064471

The mystery and magic of glia: a perspective on their roles in health and disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064471

Optimisation of region-specific reference gene selection and relative gene expression analysis methods for pre-clinical trials of Huntington's disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064471

Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064471

Striatal potassium channel dysfunction in Huntington's disease transgenic mice

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064471

The functional significance of K-complexes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064471

Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064471

Neuroglial cells: physiological properties and a potassium mediated effect of neuronal activity on the glial membrane potential

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4064471

Glial heterogeneity in expression of the inwardly rectifying K+ channel, Kir4.1, in adult rat CNS

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24686787

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

An inwardly rectifying K(+) channel, Kir4.1, expressed in astrocytes surrounds synapses and blood vessels in brain

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24686787

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NN.3691

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Dimensions Publication ID

29 July 2017

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29 July 2017

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