Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model (Q33788111)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20172694%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Ganaxolone suppression of behavioral and electrographic seizures in the mouse amygdala kindling model (English)

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18 January 2020

1 reference

1 reference

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18 January 2020

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18 January 2020

Doodipala S Reddy

1 reference

PubMed publication ID

20172694

29 July 2017

Michael A Rogawski

series ordinal

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PubMed publication ID

20172694

29 July 2017

publication date

20 February 2010

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18 January 2020

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18 January 2020

volume

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18 January 2020

issue

2-3

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18 January 2020

page(s)

254-260

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The influence of neuroactive steroid lipophilicity on GABAA receptor modulation: evidence for a low-affinity interaction

18 January 2020

cites work

1 reference

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The role of neurosteroids in the pathophysiology and treatment of catamenial epilepsy

4 July 2018

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Neurosteroid replacement therapy for catamenial epilepsy

4 July 2018

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Activation of GABAA receptors: views from outside the synaptic cleft.

4 July 2018

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4 July 2018

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Neurosteroids: endogenous regulators of the GABA(A) receptor

4 July 2018

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4 July 2018

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Allopregnanolone analogs that positively modulate GABA receptors protect against partial seizures induced by 6-Hz electrical stimulation in mice

4 July 2018

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Stress-induced deoxycorticosterone-derived neurosteroids modulate GABA(A) receptor function and seizure susceptibility.

4 July 2018

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Chronic treatment with the neuroactive steroid ganaxolone in the rat induces anticonvulsant tolerance to diazepam but not to itself

4 July 2018

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Role of AMPA and GluR5 kainate receptors in the development and expression of amygdala kindling in the mouse

4 July 2018

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Differential modulatory actions of the volatile convulsant flurothyl and its anesthetic isomer at inhibitory ligand-gated ion channels

4 July 2018

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Anticonvulsant properties of 1,4-benzodiazepine derivatives in amygdaloid-kindled seizures and their chemical structure-related anticonvulsant action

4 July 2018

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Initial human experience with ganaxolone, a neuroactive steroid with antiepileptic activity

4 July 2018

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Characterization of the anticonvulsant properties of ganaxolone (CCD 1042; 3alpha-hydroxy-3beta-methyl-5alpha-pregnan-20-one), a selective, high-affinity, steroid modulator of the gamma-aminobutyric acid(A) receptor

4 July 2018

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Progesterone receptor-mediated effects of neuroactive steroids

4 July 2018

1 reference

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Anticonvulsant activity of neurosteroids: correlation with gamma-aminobutyric acid-evoked chloride current potentiation

4 July 2018

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Development of a new pharmacological seizure model: effects of anticonvulsants on cortical- and amygdala-kindled seizures in the rat.

4 July 2018

1 reference

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A permanent change in brain function resulting from daily electrical stimulation

4 July 2018

1 reference

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Modification of seizure activity by electrical stimulation. II. Motor seizure

4 July 2018

1 reference

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A comparison of the anticonvulsant effects of 1,4- and 1,5-benzodiazepines in the amygdala-kindled rat and their effects on motor function

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854307

Experimental models of temporal lobe epilepsy: new insights from the study of kindling and synaptic reorganization

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854307

Lack of changes in seizure susceptibility during the estrous cycle in kindled rats

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854307

Behavioral analysis of the effects of 15 anticonvulsants in the amygdaloid kindled rat

4 July 2018

1 reference

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The anticonvulsant effects of allopregnanolone against amygdala-kindled seizures in female rats

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2854307

The anticonvulsant effects of progesterone and its metabolites on amygdala-kindled seizures in male rats

30 October 2018

1 reference

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Anticonvulsant activity of progesterone and neurosteroids in progesterone receptor knockout mice.

30 October 2018

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Protective efficacy of neuroactive steroids against cocaine kindled-seizures in mice

30 October 2018

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Assessment of ganaxolone's anticonvulsant activity using a randomized, double-blind, presurgical trial design. Ganaxolone Presurgical Study Group.

30 October 2018

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Enhanced anticonvulsant activity of ganaxolone after neurosteroid withdrawal in a rat model of catamenial epilepsy.

30 October 2018

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Effect of ganaxolone on flurothyl seizures in developing rats

30 October 2018

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Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure-kindled mice: comparison with diazepam and valproate

30 October 2018

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Corneal kindling in mice: behavioral and pharmacological differences to conventional kindling

30 October 2018

1 reference

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The effect of progesterone on kindling: a developmental study.

30 October 2018

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Anticonvulsant drugs and their antagonism of kindled amygdaloid seizures in rats

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20172694

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Is amygdala kindling in rats a model for drug-resistant partial epilepsy?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20172694

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.EPLEPSYRES.2010.01.009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20172694%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20172694%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

PubMed publication ID

20172694

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20172694%20AND%20SRC:MED&resulttype=core&format=json