Neurosteroids: endogenous regulators of the GABA(A) receptor (Q28256904)

Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine

21 April 2017

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Insensitivity to anaesthetic agents conferred by a class of GABA(A) receptor subunit

21 April 2017

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Pharmacological characterization of a novel cell line expressing human alpha(4)beta(3)delta GABA(A) receptors

21 April 2017

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Receptor trafficking and synaptic plasticity

21 April 2017

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The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid

21 April 2017

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Brain 5alpha-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation

21 April 2017

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Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes

21 April 2017

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Brain allopregnanolone regulates the potency of the GABAA receptor agonist muscimol

21 April 2017

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Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors

21 April 2017

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Excitatory actions of gaba during development: the nature of the nurture

21 April 2017

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Non-genomic and genomic effects of steroids on neural activity

21 April 2017

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Potentiation of inhibition by general anaesthetics in neurones of the olfactory cortex in vitro.

21 January 2018

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Modulation of the GABA receptor complex by a steroid anaesthetic

21 January 2018

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Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex

21 January 2018

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Neurosteroids and GABAA receptor function.

21 January 2018

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Slow actions of neuroactive steroids at GABAA receptors.

21 January 2018

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Neuroactive steroids: potential therapeutic use in neurological and psychiatric disorders

21 January 2018

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Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties

21 January 2018

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Antinociceptive properties of neurosteroids IV: pilot study demonstrating the analgesic effects of alphadolone administered orally to humans

21 January 2018

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Stress-induced elevations of gamma-aminobutyric acid type A receptor-active steroids in the rat brain

21 January 2018

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Steroid hormones and neurosteroids in normal and pathological aging of the nervous system.

21 January 2018

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Ethanol regulation of gamma-aminobutyric acid A receptors: genomic and nongenomic mechanisms

21 January 2018

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Brain steroidogenesis mediates ethanol modulation of GABAA receptor activity in rat hippocampus.

21 January 2018

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Neurosteroidogenesis: relevance to neurosteroid actions in brain and modulation by psychotropic drugs

21 January 2018

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Neurosteroid modulation of GABAA receptors

21 January 2018

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Phosphorylation influences neurosteroid modulation of synaptic GABAA receptors in rat CA1 and dentate gyrus neurones

21 January 2018

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GABA(A) receptor delta subunit deletion prevents neurosteroid modulation of inhibitory synaptic currents in cerebellar neurons.

21 January 2018

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Effects of a naturally occurring neurosteroid on GABAA IPSCs during development in rat hippocampal or cerebellar slices.

21 January 2018

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Plasticity in fast synaptic inhibition of adult oxytocin neurons caused by switch in GABA(A) receptor subunit expression

21 January 2018

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Pharmacological plasticity of GABA(A) receptors at dentate gyrus synapses in a rat model of temporal lobe epilepsy.

21 January 2018

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Inter-ictal and post-ictal circulating levels of allopregnanolone, an anticonvulsant metabolite of progesterone, in epileptic children

21 January 2018

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Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors

21 January 2018

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Aspects of the homeostaic plasticity of GABAA receptor-mediated inhibition

21 January 2018

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Formation and plasticity of GABAergic synapses: physiological mechanisms and pathophysiological implications.

21 January 2018

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Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.

21 January 2018

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Tonic and spillover inhibition of granule cells control information flow through cerebellar cortex

21 January 2018

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Intact synaptic GABAergic inhibition and altered neurosteroid modulation of thalamic relay neurons in mice lacking delta subunit.

21 January 2018

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Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors

21 January 2018

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The influence of subunit composition on the interaction of neurosteroids with GABA(A) receptors

21 January 2018

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Overexpression of the GABA(A) receptor epsilon subunit results in insensitivity to anaesthetics

21 January 2018

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Constructing inhibitory synapses

21 January 2018

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Protein kinase C regulation of GABAA receptors

21 January 2018

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Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses.

21 January 2018

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Supersensitivity to allosteric GABA(A) receptor modulators and alcohol in mice lacking PKCepsilon

21 January 2018

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Decreased anxiety-like behavior, reduced stress hormones, and neurosteroid supersensitivity in mice lacking protein kinase Cepsilon.

21 January 2018

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Regional distribution of cytosolic and particulate 5alpha-dihydroprogesterone 3alpha-hydroxysteroid oxidoreductases in female rat brain

21 January 2018

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On the putative physiological role of allopregnanolone on GABA(A) receptor function

21 January 2018

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Production of 5alpha-reduced neurosteroids is developmentally regulated and shapes GABA(A) miniature IPSCs in lamina II of the spinal cord.

21 January 2018

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Modulation of GABAergic synaptic transmission by the non-benzodiazepine anxiolytic etifoxine.

21 January 2018

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Selective antagonism of 5alpha-reduced neurosteroid effects at GABA(A) receptors

21 January 2018

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Benzodiazepine receptor protein identified and visualized in brain tissue by a photoaffinity label

21 January 2018

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The major site of photoaffinity labeling of the gamma-aminobutyric acid type A receptor by [3H]flunitrazepam is histidine 102 of the alpha subunit.

21 January 2018

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Photoaffinity labeling with a neuroactive steroid analogue. 6-azi-pregnanolone labels voltage-dependent anion channel-1 in rat brain.

21 January 2018

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Neuroactive steroid interactions with voltage-dependent anion channels: lack of relationship to GABA(A) receptor modulation and anesthesia

21 January 2018

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Neurosteroids act on the GABA(A) receptor at sites on the N-terminal side of the middle of TM2.

21 January 2018

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A single M1 residue in the beta2 subunit alters channel gating of GABAA receptor in anesthetic modulation and direct activation

21 January 2018

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Insight into the mechanism of action of neuroactive steroids

21 January 2018

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A single amino acid confers barbiturate sensitivity upon the GABA rho 1 receptor

21 January 2018

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Benzodiazepines act on GABAA receptors via two distinct and separable mechanisms

21 January 2018

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General anaesthetic action at transmitter-gated inhibitory amino acid receptors

21 January 2018

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Sites of positive allosteric modulation by neurosteroids on ionotropic gamma-aminobutyric acid receptor subunits

21 January 2018

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Neuroactive steroids have multiple actions to potentiate GABAA receptors

21 January 2018

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Ethanol enhances alpha 4 beta 3 delta and alpha 6 beta 3 delta gamma-aminobutyric acid type A receptors at low concentrations known to affect humans

21 January 2018

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Low ethanol concentrations selectively augment the tonic inhibition mediated by delta subunit-containing GABAA receptors in hippocampal neurons.

21 January 2018

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Effect of acute ethanol administration and acute allopregnanolone administration on spontaneous hippocampal pyramidal cell neural activity

21 January 2018

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Low doses of ethanol and a neuroactive steroid positively interact to modulate rat GABA(A) receptor function

21 January 2018

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Characterization of the discriminative stimulus effects of gamma-hydroxybutyric acid as a means for unraveling the neurochemical basis of gamma-hydroxybutyric acid actions and its similarities to those of ethanol

21 January 2018

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Gamma-hydroxybutyrate: an emerging drug of abuse that causes physical dependence

21 January 2018

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Fluoxetine and norfluoxetine stereospecifically facilitate pentobarbital sedation by increasing neurosteroids

21 January 2018

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Modulation of the GABAA receptor by depressant barbiturates and pregnane steroids

21 January 2018

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Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type III (AKR1C2).

21 January 2018

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Ovarian hormones, anticonvulsant drugs, and seizures during the menstrual cycle in women with epilepsy

21 January 2018

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Seizure exacerbation associated with inhibition of progesterone metabolism

21 January 2018

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Role of neurosteroids in catamenial epilepsy.

21 January 2018

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Catamenial epilepsy: a review

21 January 2018

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Is there more to GABA than synaptic inhibition?

21 January 2018

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Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone

21 January 2018

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Neurosteroid quantification in human brain regions: comparison between Alzheimer's and nondemented patients.

21 January 2018

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Decreased plasma and cerebrospinal fluid content of neuroactive steroids in Parkinson's disease.

21 January 2018

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Analysis of GABAA receptor function and dissection of the pharmacology of benzodiazepines and general anesthetics through mouse genetics

21 January 2018

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Molecular and neuronal substrates for general anaesthetics

21 January 2018

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Subunit composition, distribution and function of GABA(A) receptor subtypes

21 January 2018

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Analysis of the set of GABA(A) receptor genes in the human genome.

21 January 2018

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Techniques: Use of concatenated subunits for the study of ligand-gated ion channels.

21 January 2018

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Specific GABA(A) circuits in brain development and therapy.

21 January 2018

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Biosynthesis and action of neurosteroids

21 January 2018

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Oxytocin regulates neurosteroid modulation of GABA(A) receptors in supraoptic nucleus around parturition.

31 March 2020

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Neuronally restricted RNA splicing regulates the expression of a novel GABAA receptor subunit conferring atypical functional properties [corrected; erratum to be published]

31 March 2020

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Enhanced neurosteroid potentiation of ternary GABA(A) receptors containing the delta subunit.

31 March 2020

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Neurosteroids shift partial agonist activation of GABA(A) receptor channels from low- to high-efficacy gating patterns.

31 March 2020

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The contraceptive agent Provera enhances GABA(A) receptor-mediated inhibitory neurotransmission in the rat hippocampus: evidence for endogenous neurosteroids?

31 March 2020

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The C terminus of the human nicotinic alpha4beta2 receptor forms a binding site required for potentiation by an estrogenic steroid.

31 March 2020

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The socially-isolated mouse: a model to study the putative role of allopregnanolone and 5α-dihydroprogesterone in psychiatric disorders

31 March 2020

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The neurosteroid 3 alpha-hydroxy-5 alpha-pregnan-20-one induces cytoarchitectural regression in cultured fetal hippocampal neurons

31 March 2020

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Perinatal neurosteroid levels influence GABAergic interneuron localization in adult rat prefrontal cortex.

31 March 2020

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Slow death of postnatal hippocampal neurons by GABA(A) receptor overactivation

31 March 2020

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Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms.

31 March 2020

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Modulation of the GABAA receptor by progesterone metabolites.

31 March 2020

1 reference