SOX2 expression is an early event in a murine model of EGFR mutant lung cancer and promotes proliferation of a subset of EGFR mutant lung adenocarcinoma cell lines. (Q33757287)

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English	SOX2 expression is an early event in a murine model of EGFR mutant lung cancer and promotes proliferation of a subset of EGFR mutant lung adenocarcinoma cell lines.	scientific article

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14 March 2020

SOX2 expression is an early event in a murine model of EGFR mutant lung cancer and promotes proliferation of a subset of EGFR mutant lung adenocarcinoma cell lines (English)

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14 March 2020

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14 March 2020

Emily Anne Smith Bergbower

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Irem Dogan

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14 March 2020

Shigeru Kawabata

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14 March 2020

Emily Bergbower

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14 March 2020

Joell J Gills

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14 March 2020

Abdullah Ekmekci

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14 March 2020

Willie Wilson

6

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14 March 2020

Phillip A Dennis

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14 March 2020

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29 March 2014

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14 March 2020

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14 March 2020

85

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14 March 2020

1

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14 March 2020

1-6

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14 March 2020

Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers

1 reference

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Sox2 enhances the tumorigenicity and chemoresistance of cancer stem-like cells derived from gastric cancer

1 reference

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β-Catenin/POU5F1/SOX2 transcription factor complex mediates IGF-I receptor signaling and predicts poor prognosis in lung adenocarcinoma

1 reference

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Sox2 is an androgen receptor-repressed gene that promotes castration-resistant prostate cancer

1 reference

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Multiple pluripotent stem cell markers in human anaplastic thyroid cancer: the putative upstream role of SOX2.

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21 June 2018

EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer

1 reference

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Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

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SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells

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Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial

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Hypoxia induces CD133 expression in human lung cancer cells by up-regulation of OCT3/4 and SOX2

1 reference

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Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile

1 reference

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21 June 2018

SOX2 is overexpressed in stem-like cells of human lung adenocarcinoma and augments the tumorigenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4058091

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Epithelial to mesenchymal transition by TGFβ-1 induction increases stemness characteristics in primary non small cell lung cancer cell line

1 reference

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21 June 2018

Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer

1 reference

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21 June 2018

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1 reference

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21 June 2018

Global cancer statistics

1 reference

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21 June 2018

Coexpression of Oct4 and Nanog enhances malignancy in lung adenocarcinoma by inducing cancer stem cell-like properties and epithelial-mesenchymal transdifferentiation.

1 reference

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Phosphorylation of Sox2 Cooperates in Reprogramming to Pluripotent Stem Cells

1 reference

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1 reference

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Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung

1 reference

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SOX2 is an oncogene activated by recurrent 3q26.3 amplifications in human lung squamous cell carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4058091

21 June 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4058091

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SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4058091

21 June 2018

Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors

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1 reference

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24746758

12 December 2020

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The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasia

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https://pubmed.ncbi.nlm.nih.gov/24746758

12 December 2020

based on heuristic

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10.1016/J.LUNGCAN.2014.03.021

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14 March 2020

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14 March 2020

PubMed publication ID

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14 March 2020

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