Exosomes maintain cellular homeostasis by excreting harmful DNA from cells (Q33716401)

28508895

28 July 2017

title

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells (English)

1 reference

28 July 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28508895%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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10 June 2020

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10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28508895%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Chikashi Obuse

1 reference

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10 June 2020

Eiji Hara

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10 June 2020

Akiko Takahashi

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10 June 2020

Ryo Okada

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10 June 2020

Yuka Kawamata

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10 June 2020

Aki Hanyu

1 reference

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10 June 2020

Shin Yoshimoto

1 reference

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10 June 2020

language of work or name

English

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publication date

16 May 2017

1 reference

28508895

28 July 2017

published in

Nature Communications

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10 June 2020

volume

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10 June 2020

page(s)

15287

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ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins.

10 June 2020

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Sensing of latent EBV infection through exosomal transfer of 5'pppRNA

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Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth

21 June 2018

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DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway

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A TRP Channel Senses Lysosome Neutralization by Pathogens to Trigger Their Expulsion

21 June 2018

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Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

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cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection

21 June 2018

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DNA damage primes the type I interferon system via the cytosolic DNA sensor STING to promote anti-microbial innate immunity

21 June 2018

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Induction of PLSCR1 in a STING/IRF3-dependent manner upon vector transfection in ovarian epithelial cells

21 June 2018

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ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo

21 June 2018

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An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA

21 June 2018

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Exosomes and other extracellular vesicles in host-pathogen interactions

21 June 2018

1 reference

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Senescence and apoptosis: dueling or complementary cell fates?

21 June 2018

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Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

21 June 2018

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Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer

21 June 2018

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Standardization of sample collection, isolation and analysis methods in extracellular vesicle research

21 June 2018

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Exosomes mediate the cell-to-cell transmission of IFN-α-induced antiviral activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Modulation of B-cell exosome proteins by gamma herpesvirus infection

21 June 2018

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Lysosome-mediated processing of chromatin in senescence.

21 June 2018

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Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome

21 June 2018

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STING recognition of cytoplasmic DNA instigates cellular defense

21 June 2018

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Extracellular vesicles: exosomes, microvesicles, and friends

21 June 2018

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Exosomes: looking back three decades and into the future

21 June 2018

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Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway

21 June 2018

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Syndecan-syntenin-ALIX regulates the biogenesis of exosomes

21 June 2018

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Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

21 June 2018

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Isolation and characterization of RNA-containing exosomes

21 June 2018

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Four faces of cellular senescence

21 June 2018

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Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences

21 June 2018

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The essence of senescence

21 June 2018

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Secretory mechanisms and intercellular transfer of microRNAs in living cells

21 June 2018

1 reference

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Stimulator of IFN gene is critical for induction of IFN-beta during Chlamydia muridarum infection

21 June 2018

1 reference

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Senescence in tumours: evidence from mice and humans

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Rab27a and Rab27b control different steps of the exosome secretion pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Senescence-associated exosome release from human prostate cancer cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Proteomic profiling of exosomes: current perspectives

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Chemokine signaling via the CXCR2 receptor reinforces senescence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Ceramide triggers budding of exosome vesicles into multivesicular endosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Isolation and characterization of exosomes from cell culture supernatants and biological fluids

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Visualizing the dynamics of p21(Waf1/Cip1) cyclin-dependent kinase inhibitor expression in living animals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Cellular senescence: when bad things happen to good cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Mitogenic signalling and the p16INK4a-Rb pathway cooperate to enforce irreversible cellular senescence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

DNA damage signaling and p53-dependent senescence after prolonged beta-interferon stimulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Lethal anemia caused by interferon-beta produced in mouse embryos carrying undigested DNA

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Reversal of human cellular senescence: roles of the p53 and p16 pathways

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Requirement of DNase II for definitive erythropoiesis in the mouse fetal liver

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

MaRX: an approach to genetics in mammalian cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5440838

Crosstalk between the Rb pathway and AKT signaling forms a quiescence-senescence switch

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15287

Programmed cell senescence during mammalian embryonic development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15287

Senescence is a developmental mechanism that contributes to embryonic growth and patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15287

DNA damage signaling triggers degradation of histone methyltransferases through APC/C(Cdh1) in senescent cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15287

The tumor-suppressive functions of the human INK4A locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15287

Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15287

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15287

A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS15287

21 January 2018

Identifiers

DOI

10.1038/NCOMMS15287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28508895%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 June 2020

ADS bibcode

2017NatCo...815287T

0 references

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28508895%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

28508895

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28508895%20AND%20SRC:MED&resulttype=core&format=json