Inhibition of sarcolemmal FAT/CD36 by sulfo-N-succinimidyl oleate rapidly corrects metabolism and restores function in the diabetic heart following hypoxia/reoxygenation (Q33705758)

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English	Inhibition of sarcolemmal FAT/CD36 by sulfo-N-succinimidyl oleate rapidly corrects metabolism and restores function in the diabetic heart following hypoxia/reoxygenation	scientific article

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18 March 2020

Inhibition of sarcolemmal FAT/CD36 by sulfo-N-succinimidyl oleate rapidly corrects metabolism and restores function in the diabetic heart following hypoxia/reoxygenation (English)

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18 March 2020

Carolyn A. Carr

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18 March 2020

Damian J. Tyler

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18 March 2020

author name string

Latt S Mansor

1

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18 March 2020

Maria da Luz Sousa Fialho

2

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18 March 2020

Georgina Yea

3

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18 March 2020

Will A Coumans

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18 March 2020

James A West

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18 March 2020

Matthew Kerr

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18 March 2020

Joost J F P Luiken

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18 March 2020

Jan F C Glatz

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18 March 2020

Rhys D Evans

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18 March 2020

Kieran Clarke

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18 March 2020

Lisa C Heather

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18 March 2020

Julian L Griffin

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18 March 2020

publication date

1 June 2017

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18 March 2020

Cardiovascular Research

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18 March 2020

113

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18 March 2020

7

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18 March 2020

737-748

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18 March 2020

Assessment of myocardial metabolic flexibility and work efficiency in human type 2 diabetes using 16-[18F]fluoro-4-thiapalmitate, a novel PET fatty acid tracer

1 reference

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14 July 2018

Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and Echocardiography Study

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14 July 2018

Type 2 diabetes and incidence of cardiovascular diseases: a cohort study in 1·9 million people

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14 July 2018

Impaired cytosolic NADH shuttling and elevated UCP3 contribute to inefficient citric acid cycle flux support of postischemic cardiac work in diabetic hearts

1 reference

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14 July 2018

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

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14 July 2018

Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin.

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14 July 2018

Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina).

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14 July 2018

Regulation and dysregulation of glucose transport in cardiomyocytes

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14 July 2018

CD36 inhibition prevents lipid accumulation and contractile dysfunction in rat cardiomyocytes

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14 July 2018

Systematic review of the association between lung function and Type 2 diabetes mellitus

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14 July 2018

Rodent models of diabetic cardiomyopathy.

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14 July 2018

Impaired contractile function and mitochondrial respiratory capacity in response to oxygen deprivation in a rat model of pre-diabetes

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14 July 2018

Modification of myocardial substrate use as a therapy for heart failure

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14 July 2018

Prevalence of obstructive sleep apnoea in men with type 2 diabetes

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14 July 2018

Cardiac metabolism in mice: tracer method developments and in vivo application revealing profound metabolic inflexibility in diabetes

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14 July 2018

Reduction of hepatic and adipose tissue glucocorticoid receptor expression with antisense oligonucleotides improves hyperglycemia and hyperlipidemia in diabetic rodents without causing systemic glucocorticoid antagonism

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14 July 2018

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

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14 July 2018

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30 October 2018

A simple method for the isolation and purification of total lipides from animal tissues

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14 July 2018

A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

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14 July 2018

Sulfo-N-succinimidyl esters of long chain fatty acids specifically inhibit fatty acid translocase (FAT/CD36)-mediated cellular fatty acid uptake

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14 July 2018

A comparison of cell and tissue extraction techniques using high-resolution 1H-NMR spectroscopy

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14 July 2018

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

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14 July 2018

Binding of sulfosuccinimidyl fatty acids to adipocyte membrane proteins: isolation and amino-terminal sequence of an 88-kD protein implicated in transport of long-chain fatty acids

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14 July 2018

Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. Homology with human CD36

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14 July 2018

Labeling of adipocyte membranes by sulfo-N-succinimidyl derivatives of long-chain fatty acids: Inhibition of fatty acid transport

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14 July 2018

Altered myocardial substrate metabolism and decreased diastolic function in nonischemic human diabetic cardiomyopathy: studies with cardiac positron emission tomography and magnetic resonance imaging

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21 January 2018

Effect of non-insulin-dependent diabetes mellitus on myocardial insulin responsiveness in patients with ischemic heart disease

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21 January 2018

Effect of obesity and insulin resistance on myocardial substrate metabolism and efficiency in young women

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21 January 2018

Perfused hearts from Type 2 diabetic (db/db) mice show metabolic responsiveness to insulin

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21 January 2018

Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts.

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21 January 2018

Increased O2 cost of basal metabolism and excitation-contraction coupling in hearts from type 2 diabetic mice

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21 January 2018

Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation

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21 January 2018

Changes in fatty acid transport and transporters are related to the severity of insulin deficiency

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21 January 2018

Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment

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Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36.

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21 January 2018

Adenosine monophosphate-activated protein kinase activation, substrate transporter translocation, and metabolism in the contracting hyperthyroid rat heart

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21 January 2018

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

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Short- and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy

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30 October 2018

CD36 Deficiency Rescues Lipotoxic Cardiomyopathy

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21 January 2018

A metabolic role for mitochondria in palmitate-induced cardiac myocyte apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/28419197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased susceptibility to hypoxia of prolonged action potential duration in ventricular papillary muscles from diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/28419197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of anoxia and low free fatty acid on myocardial energy metabolism in streptozotocin-diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/28419197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

N-hydroxysulfosuccinimide active esters: bis(N-hydroxysulfosuccinimide) esters of two dicarboxylic acids are hydrophilic, membrane-impermeant, protein cross-linkers

1 reference

https://pubmed.ncbi.nlm.nih.gov/28419197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid transporter levels and palmitate oxidation rate correlate with ejection fraction in the infarcted rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/28419197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms responsible for enhanced fatty acid utilization by perfused hearts from type 2 diabeticdb/dbmice

1 reference

https://pubmed.ncbi.nlm.nih.gov/28419197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of glucose transporter 4 diminishes electrical activity of mouse hearts during hypoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/28419197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurements of fatty acid and carbohydrate metabolism in the isolated working rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/28419197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

First clinical trial with etomoxir in patients with chronic congestive heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/28419197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improvement of myocardial function and metabolism in diabetic rats by the carnitine palmitoyl transferase inhibitor Etomoxir

1 reference

https://pubmed.ncbi.nlm.nih.gov/28419197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake and metabolism of palmitate by isolated cardiac myocytes from adult rats: involvement of sarcolemmal proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/28419197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Effects of Hypertrophy and Diabetes on Cardiac Pyruvate Dehydrogenase Activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/28419197

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/CVR/CVX045

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28419197%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28419197%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28419197%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

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