Lysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligase (Q33652051)

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12 March 2020

title

Lysine 27 ubiquitination of the mitochondrial transport protein Miro is dependent on serine 65 of the Parkin ubiquitin ligase (English)

1 reference

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12 March 2020

main subject

protein ubiquitination

1 reference

1 reference

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12 March 2020

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Kailash Phatechand Bhatia

12 March 2020

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12 March 2020

1 reference

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12 March 2020

David Komander

1 reference

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12 March 2020

Helene Plun-Favreau

1 reference

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12 March 2020

Rosalind Norkett

1 reference

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12 March 2020

Tobias Wauer

1 reference

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12 March 2020

Hsiu-Chuan Wu

1 reference

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12 March 2020

Warren D Hirst

1 reference

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12 March 2020

Thomas Foltynie

1 reference

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12 March 2020

language of work or name

English

0 references

publication date

26 March 2014

1 reference

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Journal of Biological Chemistry

12 March 2020

published in

1 reference

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12 March 2020

volume

289

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issue

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12 March 2020

page(s)

14569-14582

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describes a project that uses

12 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4031514/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis

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OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin

28 July 2018

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PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria

28 July 2018

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Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

28 July 2018

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PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

28 July 2018

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Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

28 July 2018

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PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65

28 July 2018

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28 July 2018

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Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria

28 July 2018

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Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons

28 July 2018

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An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains

28 July 2018

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Systematic and quantitative assessment of the ubiquitin-modified proteome

28 July 2018

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Autoregulation of Parkin activity through its ubiquitin-like domain

28 July 2018

1 reference

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Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane

28 July 2018

1 reference

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Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

28 July 2018

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Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy

28 July 2018

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Parkin ubiquitinates Drp1 for proteasome-dependent degradation: implication of dysregulated mitochondrial dynamics in Parkinson disease

28 July 2018

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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

28 July 2018

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PINK1 cleavage at position A103 by the mitochondrial protease PARL.

28 July 2018

1 reference

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The mitochondrial fusion-promoting factor mitofusin is a substrate of the PINK1/parkin pathway

28 July 2018

1 reference

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Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex

28 July 2018

1 reference

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Monomeric red fluorescent proteins with a large Stokes shift

28 July 2018

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Drosophila parkin requires PINK1 for mitochondrial translocation and ubiquitinates mitofusin

28 July 2018

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Delivery of GABAARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin.

28 July 2018

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PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

28 July 2018

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PINK1-dependent recruitment of Parkin to mitochondria in mitophagy

28 July 2018

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Virus-Induced Chaperone-Enriched (VICE) domains function as nuclear protein quality control centers during HSV-1 infection

28 July 2018

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PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death

28 July 2018

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Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking

28 July 2018

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28 July 2018

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GTPase dependent recruitment of Grif-1 by Miro1 regulates mitochondrial trafficking in hippocampal neurons

28 July 2018

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Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase

28 July 2018

1 reference

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

28 July 2018

1 reference

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PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons

28 July 2018

1 reference

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The atypical Rho GTPases Miro-1 and Miro-2 have essential roles in mitochondrial trafficking

28 July 2018

1 reference

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GRIF-1 and OIP106, members of a novel gene family of coiled-coil domain proteins: association in vivo and in vitro with kinesin

28 July 2018

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Huntingtin-associated protein 1 regulates inhibitory synaptic transmission by modulating gamma-aminobutyric acid type A receptor membrane trafficking

28 July 2018

1 reference

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Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin

28 July 2018

1 reference

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Atypical Rho GTPases have roles in mitochondrial homeostasis and apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031514

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031514

Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses.

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563031

Drosophila Miro is required for both anterograde and retrograde axonal mitochondrial transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563031

Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563031

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563031

PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563031

Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563031

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563031

Alterations in the common fragile site gene Parkin in ovarian and other cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563031

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563031

21 January 2018

Identifiers

DOI

10.1074/JBC.M114.563031

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24671417%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24671417%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

24671417

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24671417%20AND%20SRC:MED&resulttype=core&format=json