Insights into cancer from transgenic mouse models (Q33643327)

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Transgenic mice as probes into complex systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Transgenic models of tumor development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Antioncogenes and human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Tumor suppressor gene mutations in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Effects of an Rb mutation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Requirement for a functional Rb-1 gene in murine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Tumor spectrum analysis in p53-mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Role of the INK4a locus in tumor suppression and cell mortality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Tumor suppressor mutations in mice: the next generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

The multistep nature of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Lessons from hereditary colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A causal role for E-cadherin in the transition from adenoma to carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Cadherins in cancer: implications for invasion and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

E-cadherin germline mutations in familial gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Expression of cyclin D1 in epithelial tissues of transgenic mice results in epidermal hyperproliferation and severe thymic hyperplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

TGFbeta1 inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Bovine papillomavirus genome elicits skin tumours in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Retinoblastoma in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Second primary neoplasms in patients with retinoblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Deletions of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

p107 is a suppressor of retinoblastoma development in pRb-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Mutations in the p53 gene occur in diverse human tumour types

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

p53 mutations in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Suppression of human colorectal carcinoma cell growth by wild-type p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

p53 and the Li-Fraumeni syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A novel protein with strong homology to the tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Transgenic mice with p53-responsive lacZ: p53 activity varies dramatically during normal development and determines radiation and drug sensitivity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Transgenic mouse model for studying the transcriptional activity of the p53 protein: age- and tissue-dependent changes in radiation-induced activation during embryogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Cancer. p53, guardian of the genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

p53 is required for radiation-induced apoptosis in mouse thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Thymocyte apoptosis induced by p53-dependent and independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Tissue-specific inactivation of p53 tumor suppression in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

An apoptotic defect in lens differentiation caused by human p53 is rescued by a mutant allele

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Regulation of p53 stability by Mdm2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Mdm2 promotes the rapid degradation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

p53 modulation of TFIIH–associated nucleotide excision repair activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

21 January 2018

p53: puzzle and paradigm

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

p53, the cellular gatekeeper for growth and division

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Identification of p53 as a sequence-specific DNA-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Regulation of the specific DNA binding function of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Transcriptional activation by wild-type but not transforming mutants of the p53 anti-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Presence of a potent transcription activating sequence in the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Growth factor modulation of p53-mediated growth arrest versus apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Sequence-specific transcriptional activation is essential for growth suppression by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

p21 is a universal inhibitor of cyclin kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Radiation-induced cell cycle arrest compromised by p21 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A p53-dependent mouse spindle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Abnormal centrosome amplification in the absence of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Essential role for p53-mediated transcription in E1A-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A model for p53-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Induction of apoptosis in HeLa cells by trans-activation-deficient p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

21 January 2018

1 reference

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A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

21 January 2018

1 reference

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

21 January 2018

1 reference

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Induction of the growth inhibitor IGF-binding protein 3 by p53

21 January 2018

1 reference

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Bax-deficient mice with lymphoid hyperplasia and male germ cell death

21 January 2018

1 reference

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Bax suppresses tumorigenesis and stimulates apoptosis in vivo

21 January 2018

1 reference

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V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

21 January 2018

1 reference

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Mutations in the p53 and SCID genes cooperate in tumorigenesis.

21 January 2018

1 reference

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The SCID mouse mutant: definition, characterization, and potential uses

21 January 2018

1 reference

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Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

21 January 2018

1 reference

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DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

21 January 2018

1 reference

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Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells

21 January 2018

1 reference

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DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

21 January 2018

1 reference

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Chromosomal translocations in human cancer.

21 January 2018

1 reference

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No requirement for V(D)J recombination in p53-deficient thymic lymphoma

21 January 2018

1 reference

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Mutation and cancer: statistical study of retinoblastoma

21 January 2018

1 reference

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Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation

21 January 2018

1 reference

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Interaction of p53 with its consensus DNA-binding site

21 January 2018

1 reference

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Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential

21 January 2018

1 reference

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

21 January 2018

1 reference

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Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells

21 January 2018

1 reference

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p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

21 January 2018

1 reference

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Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

21 January 2018

1 reference

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Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

21 January 2018

1 reference

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The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

21 January 2018

1 reference

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Double identity for proteins of the Bcl-2 family

21 January 2018

1 reference

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The t(14;18) chromosome translocations involved in B-cell neoplasms result from mistakes in VDJ joining

21 January 2018

1 reference

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Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

21 January 2018

1 reference

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Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

21 January 2018

1 reference

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Induction of apoptosis in fibroblasts by c-myc protein

21 January 2018

1 reference

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Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging

21 January 2018

1 reference

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Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.

21 January 2018

1 reference

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Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells

21 January 2018

1 reference

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A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

21 January 2018

1 reference

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Inactivation of the retinoblastoma susceptibility gene in human breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Fibroblast immortality is a prerequisite for transformation by EJ c-Ha-ras oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Function of a human cyclin gene as an oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

CDC25 phosphatases as potential human oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Increased tumor proliferation and genomic instability without decreased apoptosis in MMTV-ras mice deficient in p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Inhibition of ras-induced proliferation and cellular transformation by p16INK4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Cellular commitment to oncogene-induced transformation or apoptosis is dependent on the transcription factor IRF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Mutations and altered expression of p16INK4 in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A novel cyclin encoded by a bcl1-linked candidate oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Cyclin D1 provides a link between development and oncogenesis in the retina and breast

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Early loss of the retinoblastoma gene is associated with impaired growth inhibitory innervation during melanotroph carcinogenesis in Rb+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

CDK-independent activation of estrogen receptor by cyclin D1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Increased E2F1 activity induces skin tumors in mice heterozygous and nullizygous for p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A major susceptibility locus to murine lung carcinogenesis maps on chromosome 6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Site-specific recombinases: tools for genome engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Inducible gene targeting in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Inducible gene expression systems for higher eukaryotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Ligand-activated site-specific recombination in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Disruption of overlapping transcripts in the ROSA beta geo 26 gene trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

WT-1 is required for early kidney development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Embryonic lethality and radiation hypersensitivity mediated by Rad51 in mice lacking Brca2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

The tumor suppressor gene Smad4/Dpc4 is required for gastrulation and later for anterior development of the mouse embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

MSH2 deficient mice are viable and susceptible to lymphoid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Male mice defective in the DNA mismatch repair gene PMS2 exhibit abnormal chromosome synapsis in meiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Tumour susceptibility and spontaneous mutation in mice deficient in Mlh1, Pms1 and Pms2 DNA mismatch repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Mutation in the mismatch repair gene Msh6 causes cancer susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Key roles for E2F1 in signaling p53-dependent apoptosis and in cell division within developing tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Flp-mediated tissue-specific inactivation of the retinoblastoma tumor suppressor gene in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P

Sunburn and p53 in the onset of skin cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F%28SICI%291096-9896%28199901%29187%3A1%3C43%3A%3AAID-PATH246%3E3.0.CO%3B2-P