Sphingosine kinase 1 is overexpressed and promotes proliferation in human thyroid cancer (Q33636769)

28 July 2017

title

Sphingosine kinase 1 is overexpressed and promotes proliferation in human thyroid cancer (English)

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28 July 2017

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1 reference

Hongyu Guan

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28 July 2017

Liehua Liu

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28 July 2017

Junchao Cai

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28 July 2017

Juan Liu

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28 July 2017

Caisheng Ye

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28 July 2017

Mengfeng Li

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28 July 2017

Yanbing Li

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28 July 2017

publication date

22 September 2011

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28 July 2017

published in

Molecular Endocrinology

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

1858-1866

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Sphingosine kinase 1 regulates the Akt/FOXO3a/Bim pathway and contributes to apoptosis resistance in glioma cells

28 July 2017

cites work

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Sphingosine Kinase-1 Enhances Resistance to Apoptosis through Activation of PI3K/Akt/NF-κB Pathway in Human Non–Small Cell Lung Cancer

21 June 2018

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The Akt-Specific Inhibitor MK2206 Selectively Inhibits Thyroid Cancer Cells Harboring Mutations That Can Activate the PI3K/Akt Pathway

21 June 2018

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21 June 2018

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IKBKE is over‐expressed in glioma and contributes to resistance of glioma cells to apoptosis via activating NF‐κB

21 June 2018

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Sphingosine kinase-1 activity and expression in human prostate cancer resection specimens

21 June 2018

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The Sphingosine Kinase 1 Inhibitor 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole Induces Proteasomal Degradation of Sphingosine Kinase 1 in Mammalian Cells

21 June 2018

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Overexpression of sphingosine kinase 1 is associated with salivary gland carcinoma progression and might be a novel predictive marker for adjuvant therapy

21 June 2018

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Genetic alterations in the phosphatidylinositol-3 kinase/Akt pathway in thyroid cancer

21 June 2018

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Control of metabolism and signaling of simple bioactive sphingolipids: Implications in disease.

21 June 2018

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Sphingosine kinase-1 is central to androgen-regulated prostate cancer growth and survival

21 June 2018

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Targeting sphingosine kinase 1 inhibits Akt signaling, induces apoptosis, and suppresses growth of human glioblastoma cells and xenografts

21 June 2018

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Prognostic significance of integrin-linked kinase1 overexpression in astrocytoma

21 June 2018

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Sphingosine kinase 1 is associated with gastric cancer progression and poor survival of patients

21 June 2018

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Sphingosine kinase as an oncogene: autocrine sphingosine 1-phosphate modulates ML-1 thyroid carcinoma cell migration by a mechanism dependent on protein kinase C-alpha and ERK1/2.

21 June 2018

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Interleukin-1 regulates the expression of sphingosine kinase 1 in glioblastoma cells

21 June 2018

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Clinical significance of sphingosine kinase-1 expression in human astrocytomas progression and overall patient survival

21 June 2018

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Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin

21 June 2018

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Biological roles of lysophospholipid receptors revealed by genetic null mice: an update

21 June 2018

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Functions of the multifaceted family of sphingosine kinases and some close relatives

21 June 2018

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Tumor necrosis factor-alpha-stimulated cell proliferation is mediated through sphingosine kinase-dependent Akt activation and cyclin D expression

21 June 2018

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Human arrest defective 1 acetylates and activates beta-catenin, promoting lung cancer cell proliferation

21 June 2018

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Sphingosine kinase-1 as a chemotherapy sensor in prostate adenocarcinoma cell and mouse models

21 June 2018

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Sphingosine 1-phosphate and ceramide 1-phosphate: expanding roles in cell signaling

21 June 2018

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The Akt inhibitor KP372-1 suppresses Akt activity and cell proliferation and induces apoptosis in thyroid cancer cells.

21 June 2018

1 reference

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Lysophospholipid receptor-dependent and -independent calcium signaling.

21 June 2018

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Cdx1 inhibits human colon cancer cell proliferation by reducing beta-catenin/T-cell factor transcriptional activity

21 June 2018

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Sphingosine-1-phosphate: an enigmatic signalling lipid

21 June 2018

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Characterisation of the phosphorylation of beta-catenin at the GSK-3 priming site Ser45.

21 June 2018

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Enumeration of the simian virus 40 early region elements necessary for human cell transformation

21 June 2018

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An oncogenic role of sphingosine kinase

21 June 2018

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Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

21 June 2018

1 reference

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 June 2018

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

21 June 2018

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The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417174

Sphingosine kinase 1 protein and mRNA are overexpressed in non-Hodgkin lymphomas and are attractive targets for novel pharmacological interventions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417174

Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417174

Ectopic activation of lymphoid high mobility group-box transcription factor TCF-1 and overexpression in colorectal cancer cells

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21940753

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Overexpression and overactivation of Akt in thyroid carcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21940753

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1210/ME.2011-1048

1 reference

28 July 2017

1 reference

28 July 2017

1 reference